Researchers describe case of tecovirimat-resistant mpox variant in patient with prolonged infection

Authors from the Institute of Tropical Medicine, Nationalestraat, Antwerp, Belgium describe a case of tecovirimat-resistant mpox virus (MPXV) identified at the autopsy of a severely immunocompromised patient with prolonged disease. Tecovirimat, an antiviral used to treat severe mpox virus, has a low barrier to resistance, which makes this case particularly unusual. The case report is published in Annals of Internal Medicine.

What You Should Know About Mpox

Find out what special pathogens expert Erika Cheung, MSN, RN, CPN, has to say about the disease, which the WHO has declared a public health emergency of international concern. Since May 18, 2022, cases of mpox have been spreading in the United States, including California. On July 23, 2022, the World Health Organization (WHO) declared the current outbreak a public health emergency of international concern.