Ovarian cancer is hard to diagnose in its early stages because it has vague symptoms, such as constipation, bloating, and back pain.
Many premature infants need mechanical ventilation to breathe. However, prolonged ventilation can lead to problems like respiratory diseases or ventilation-induced injury.Jonas Naumann and Mareike Zink study the physics of mechanical stress from ventilation at Leipzig University, in Leipzig, Germany and discovered some of the mechanisms that explain why premature lungs are especially sensitive to stress.
In the United States, flu season usually occurs in the fall and winter, and while influenza viruses spread year-round, most of the time flu activity peaks between December and February. The overall impact of the flu varies from season to…
Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a mouse model study published in today’s issue of Molecular Cell, from investigators at University Hospitals (UH) and Case Western Reserve University, identifies a novel strategy to isolate the beneficial effects of β2AR stimulation. This suggests a new therapeutic approach to airway diseases as well as numerous other conditions involving the aberrant function of GPCRs.
Innate lymphoid cells (ILCs) promote lung inflammation in asthma but little is known about how they are suppressed. Researchers at University of California San Diego School of Medicine found RNA-binding protein RBM3 is increased in human and mouse ILCs during…
Tackling pollution from the emission of nitrogen compounds, particularly ammonia, could reduce many of the 23.3 million years of life that were lost prematurely across the world in 2013 due to nitrogen-related air pollution.
Opening a new chapter in a long, storied history dating back to 1905, the American Thoracic Society is pleased to announce that it has completed a major rebrand which includes a new, elevated logo design and a refreshed mission statement asserting the Society’s leadership role in driving innovation in the respiratory space.