Research team led by Case Western Reserve awarded $2.75M from Department of Defense to advance clot-stabilizing nanotechnology

The U.S. Department of Defense (DoD) has awarded a team of researchers led by Case Western Reserve University a four-year, $2.75 million grant to explore new technology to generate and stabilize a protein called fibrin that is essential to maintain protective blood clots in an injured body.

Case Western Reserve University-led research team discovers new method to test for oral cancer

A team of researchers, led by a clinician scientist at the Case Western Reserve University School of Dental Medicine, has discovered a noninvasive, low-cost test to detect oral cancer, monitor precancerous lesions and determine when a biopsy is warranted.

$2 million grant from The Roe Green Foundation catalyzes multidisciplinary research building in Uganda

For the past 38 years, Case Western Reserve University (CWRU) and University Hospitals (UH) have worked closely with a variety of institutions in Uganda to advance medical research and education across a range of fields.

Their facilities have remained scattered across the campuses of local partners but now, the collaboration will have a permanent home.

A $2 million gift from The Roe Green Foundation, jointly awarded to CWRU and UH, will advance global health initiatives from each institution and establish a state-of-the-art research hub and gathering place in Uganda’s capital, Kampala: the Case Western Reserve University and University Hospitals Roe Green Medical Education and Research Building.

Case Western Reserve University researcher awarded $3.5 million federal grant

A researcher from the Case Western Reserve University Frances Payne Bolton School of Nursing has been awarded a $3.5 million federal grant for research to improve sleep health and glucose management in young adults with type 1 diabetes. Positive findings could lead to adding the intervention in current care protocols.

Researchers at Case Western Reserve, University Hospitals to assess effectiveness of novel MRI method for breast cancer patients

Researchers at Case Western Reserve University
(CWRU) and University Hospitals (UH) will study whether a new magnetic resonance imaging exam can predict how chemotherapy’s effectiveness for a woman with breast cancer based on a single round of treatment.

CWRU School of Nursing awarded $2.56M grant from The John A. Hartford Foundation for age-friendly care program in MinuteClinic at CVS locations

With a new three-year, $2.56 million grant from The John A. Hartford Foundation, the Frances Payne Bolton School of Nursing at Case Western Reserve University will evaluate improvements in care, economic impact and equity in outcomes of 1.2 million older adults receiving “age-friendly” care at MinuteClinics nationally.

Case Western Reserve University Launches Ilumis

Case Western Reserve University (CWRU) developed the HoloAnatomy® Software Suite to teach human anatomy in a more intuitive, cost-effective way using holographic imagery. Building on its long history of bringing influential research into the public domain, CWRU has announced the launch of Ilumis, Inc. to accelerate product innovation, improve partner service, and rapidly scale the potential of this revolutionary learning platform.

Key Mechanisms of Airway Relaxation in Asthma Revealed in New Study

Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a mouse model study published in today’s issue of Molecular Cell, from investigators at University Hospitals (UH) and Case Western Reserve University, identifies a novel strategy to isolate the beneficial effects of β2AR stimulation. This suggests a new therapeutic approach to airway diseases as well as numerous other conditions involving the aberrant function of GPCRs.

Researchers Link Pollution to Cardiovascular Disease, Develop Strategies to Reduce Exposure and Encourage Government Intervention

In a new review article, published today in The New England Journal of Medicine, researchers from University Hospitals (UH), Case Western Reserve University and Boston College discuss evidence linking pollution and cardiovascular disease. The research team highlights strategies for reducing individual exposure to pollution, and the importance of government-supported interventions encouraging clean energy.

TraumaChekTM: Next step in life-saving blood-assessment technology

Scientists at Case Western Reserve University are leading the development of TraumaChekTM, a hand-held medical device to quickly assess a wounded soldier’s critical clotting issues and other blood conditions in the battlefield. The new sensor, if successful and adopted in the field, would represent the next generation of their successful ClotChip®, which emergency workers can use to measure how well a patient’s blood may clot.

TraumaChekTM: Next step in life-saving blood-assessment technology

Scientists at Case Western Reserve University are leading the development of TraumaChekTM, a hand-held medical device to quickly assess a wounded soldier’s critical clotting issues and other blood conditions in the battlefield. The new sensor, if successful and adopted in the field, would represent the next generation of their successful ClotChip®, which emergency workers can use to measure how well a patient’s blood may clot.

CWRU Scientist’s Team Receives $1.2 Million W.M. Keck Foundation Research Grant to Determine How Ecological Factors Affect Evolution

A Case Western Reserve University researcher is leading an interdisciplinary global team that will use state-of-the-art technology to tackle an ancient question: How did ecological factors affect the evolution of our ancestors millions of years ago? The possible answers so intrigued the W. M. Keck Foundation that it awarded Armington Professor Beverly Saylor and her colleagues a $1.2 million grant to explore them.

Dominick J. Casadonte Jr. Selected as 2021 CUR-Goldwater Scholars Faculty Mentor Awardee

Dominick J. Casadonte Jr., Minnie Stevens Piper Professor in the Department of Chemistry and Biochemistry at Texas Tech University, is the 2021 CUR-Goldwater Scholars Faculty Mentor Awardee.

Iowa and Ohio Researchers Discover New, Protective Strategy for Embryonic Development during Prenatal Stress in Animal Model

New research from the University of Iowa and University Hospitals Cleveland Medical Center demonstrates that offspring can be protected from the effects of prenatal stress by administering a neuroprotective compound during pregnancy.

Artificial intelligence tool for reading MRI scans could transform prostate cancer surgery and treatment

Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have preliminarily validated an artificial intelligence (AI) tool to predict how likely the disease is to recur following surgical treatment for prostate cancer.

Case Western Reserve University teams with Boehringer Ingelheim on artificial intelligence solutions for precision medicine

The Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University and Boehringer Ingelheim, one of the world’s largest pharmaceutical companies will leverage the power of CCIPD’s image computing AI solutions to identify patterns and links between cellular response and underlying molecular drivers, with the goal of advancing therapeutics for diseases with no satisfactory treatment option.

NIH Funds Research into Differences in Glioblastoma between Males and Females

A team led by researchers from Case Western Reserve University School of Medicine and Cleveland Clinic Lerner Research Institute has secured $10.4 million over five years from the National Institutes of Health/National Cancer Institute to explore at the molecular level the differences in glioblastoma between males and females.

New Research Shows Air Pollution Could Play a Role in Development of Cardiometabolic Diseases, Diabetes

Air pollution is the world’s leading environmental risk factor, and causes more than nine million deaths per year. New research published in the Journal of Clinical Investigation shows air pollution may play a role in the development of cardiometabolic diseases, such as diabetes. Importantly, the effects were reversible with cessation of exposure.

Hospital patients can do their part in COVID-19 fight

A clinical researcher, who has studied the lack of hygiene practices among hospital patients, is urging not just hospitals—but those who end up there—to do more to fight against the novel coronavirus, which had infected more than 2 million people worldwide by mid-April.

UH to launch clinical trial in the fight to protect clinicians against COVID-19

University Hospitals announced it will lead a clinical trial that involves the administration of an investigational drug, ARMS-I, to its caregivers working on the frontlines of the COVID-19 pandemic. The trial, named the ARMS-I COVID Study, is designed to assess whether the drug helps prevent airborne transmission of coronavirus and whether it reduces the symptoms of healthcare providers who have tested positive for the virus.