Hepatitis A Vaccination Required for Herd Immunity in People Experiencing Homelessness or Who Use Drugs

In the U.S., hepatitis A outbreaks are repeatedly affecting people experiencing homelessness or who use drugs. A 2017-19 Kentucky outbreak primarily among these groups resulted in 501 cases, six deaths. Vaccination efforts likely averted 30 hospitalizations and $490K in costs,…

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients

Original Investigation September 21, 2021 Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients A Randomized Clinical Trial   Author Affiliations Article Information JAMA. 2021;326(11):1024-1033. doi:10.1001/jama.2021.13355   visual abstract icon  Visual Abstract Key Points Question  Does the probiotic Lactobacillus rhamnosus GG prevent ventilator-associated pneumonia (VAP)…

Mechanistic Effects of Resistance Exercise on Cancer-induced Muscle Atrophy

Muscle atrophy is a hallmark of cancer cachexia, a complex multifactorial wasting disease highly associated with mortality. In recent years, we have learned a lot about the protective effects of exercise during cancer. Resistance exercise is now recognized as a…

Researchers at UC San Diego Identify the Skin’s Master Regulator

Researchers led by George Sen, PhD, associate professor of dermatology and cellular and molecular medicine at UC San Diego School of Medicine, have identified the master regulator controlling the expression of genes regulating how the epidermis attaches to the underlying…

COVID-19 Pandemic Hastens Cleveland Clinic’s Unified Well-Being Strategy

The COVID-19 pandemic has been a catalyst for shaping a new future in healthcare. At the Cleveland Clinic, top priorities throughout the pandemic have been to support caregivers professionally and personally and to help them be their best for themselves, their fellow caregivers, patients, organizations, and communities.

How High Do We Go?

Inferior Mesenteric Artery Versus Superior Rectal Artery Ligation This study, which was published in the October 2021 issues of DISEASES OF THE COLON AND RECTUM, was conducted at 6 tertiary referral centers in the United States (Emory University, University of…

Taking a Break from Dieting Reduces Hunger, Increases Adherence to Diet with No Detriment to Fat or Weight Loss

A sustained energy deficit with restricted food intake and increased physical activity is accepted as a reliable means to reduce body weight and body fat. However, most individuals find maintaining adherence to these conditions difficult in the face of increasing…

What Factors Put Runners at Risk for Exertional Heat Stroke During a Marathon?

Exertional heat stroke (EHS) can develop in participants at running events. A runner with EHS overheats beyond their capacity to cool and can suffer organ damage, and even death, if not rapidly cooled. Understanding the factors that may lead to…

Protein Inhibitor May Lead to New Treatment for Low Oxygen Associated with Sleep Apnea

Article title: Lysine demethylase KDM6B regulates HIF-1α mediated systemic and cellular responses to intermittent hypoxia Authors: Jayasri Nanduri, Ning Wang, Benjamin L. Wang, Nanduri R. Prabhakar From the authors: “[The] current study demonstrates that pharmacological disruption of [Hypoxia-inducible factor]-1α activation…

Exercise May Not Offset Genetic Predisposition for Low Exercise Capacity, Impaired Insulin Sensitivity

Article title: Genetically determined exercise capacity affects systemic glucose response to insulin in rats Authors: Michael Schwarzer, Annika Molis, Christina Schenkl, Andrea Schrepper, Steven L. Britton, Lauren Gerard Koch, Torsten Doenst From the authors: “In our model of [high capacity…

Researchers Develop Novel Analog Processor for High Performance Computing

Analog photonic solutions offer unique opportunities to address complex computational tasks with unprecedented performance in terms of energy dissipation and speeds, overcoming current limitations of modern computing architectures based on electron flows and digital approaches.  In a new study published…

New Study Provides Structural Insights into How Cholesterol in the Brain Regulates Ion Channels and Alters Their Function; Findings Could Facilitate the Development of Therapeutics for Neurological Diseases

UNDER EMBARGO UNTIL 11am EST on August 24: Cell Reports   Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai,…

First of its kind study using multi-omics approach identifies large list of candidate genes associated with alcohol use disorder

New York, NY (Aug 20, 2021) – Researchers from the Icahn School of Medicine at Mount Sinai have published the first study of its kind in the field of addiction genetics using a multi-omics approach to provide a large list…

GIS in the jungle: Experiential Environmental Education (EEE) in Panama

“GIS in the Jungle,” reflects University of Redlands Professor Monty Hempel’s legacy promoting Experiential Environmental Education (EEE). PanaMapping is an
“Environmental Design Studio,” a type of course which
Monty and his colleagues established at the University
of Redlands to allow students to practice their GIS skills
to analyze environmental problems and to develop solutions to environmental challenges outside the classroom.