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UrduCLEVELAND: A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than 1 in 5,000 people worldwide.
Tag: Hematology
Sysmex America to Exhibit Latest Automation & Innovation for Workflow Efficiency at ADLM 2024
Sysmex America, Inc., a leading diagnostic solutions company offering hematology, hemostasis, urinalysis, flow cytometry and informatic solutions, will be exhibiting virtually and live at the ADLM 2024, July 28 – August 1.
Emma Guttman-Yassky, MD, PhD, Receives High Honor at European Academy of Allergy and Clinical Immunology
The Paul Ehrlich Award for Experimental Research recognizes scientists who have revolutionized the understanding of allergic diseases and immunological mechanisms.
Children’s Hospital Los Angeles Study Finds Many Kids With Sickle Cell Anemia Lack Preventative Care
Press Release EMBARGOED until Wednesday, March 6, 12:05 AM EST LOS ANGELES (March 6, 2024)—Children with sickle cell anemia are vulnerable to serious infections and stroke, but many do not receive the preventative care that could help them stay healthier…
JMIR Perioperative Medicine Invites Submissions on Perioperative Blood Management
JMIR Publications is pleased to announce a new theme issue titled “Perioperative Blood Management” in JMIR Perioperative Medicine.
NIH Awards Mount Sinai Researchers $12 Million to Personalize Sickle Cell Treatment
The Mount Sinai Health System has received a $12,180,625 grant from the National Heart, Lung and Blood Institute to compare new treatment options for sickle cell disease and determine which work best for specific patients.
Common Cold Virus Linked to Potentially Fatal Blood Clotting Disorder
The new observation, made by UNC School of Medicine’s Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.
Novel Gene Therapy Proving Safe and Successful in Sickle Cell Patients Treated at Cleveland Clinic Children’s
Researchers presenting preliminary data from a clinical trial aimed at discovering a cure for sickle cell disease reveal positive results among its first patients. Sickle cell disease, a genetic blood disorder, is a painful and debilitating condition for which there are few approved therapies.
A promising outlook: CAR T cells improve patient quality of life
Chimeric antigen receptor T-cell (CAR-T) therapy has transformed cancer treatment, yet relatively few studies have investigated the impact of the therapy on longitudinal patient quality of life – an aspect of care that often suffers from receiving traditional intensive cancer medications, such as chemotherapy.
COVID vaccine induces robust T cell responses in blood cancer patients
Researchers found that, despite being heavily immunocompromised, haematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.
Tulane expert lauds new ‘cutting edge’ hemophilia treatment
A new treatment that helps people with hemophilia A maintain higher levels of a crucial blood clotting factor with fewer treatments is a victory for patients, according to a new editorial in The New England Journal of Medicine this week by Dr. Cindy…
Sylvester Comprehensive Cancer Center Receives Approval to Build World-Class Myeloma Research Institute
The Myeloma Research Institute’s launch follows many important accomplishments by C. Ola Landgren, M.D., Ph.D. and his team, who are dedicated to fulfilling a promise of providing the best cancer care to myeloma patients. Florida is among the states with the highest rates of new myeloma diagnoses in the U.S., with 7.9 cases diagnosed in every 100,000 of the state’s residents.
UC San Diego Sanford Stem Cell Institute Launches Stem Cells Into Space
The UC San Diego Sanford Stem Cell Institute leads its first space launch, sending stem cells into space aboard the International Space Station. The NASA-partnered study will take advantage of the microgravity environment of space to study accelerated aging in stem cells.
In His Blood
A former fellow at the UNM Comprehensive Cancer Center, Dr. Shashank Cingam comes back to New Mexico to Treat blood cancers.
Ramiro Garzon, MD, to Lead Hematologic Cancers at Huntsman Cancer Institute and University of Utah Health
A national authority in hematology will soon lead Hematology and Hematological Malignancies at Huntsman Cancer Institute and University of Utah Health. Dr. Ramiro Garzon’s focus is patients with leukemia and researching the molecular mechanisms of these cancers. Garzon’s major focuses include developing new treatment for cancers that begin in blood forming tissue such as the bone marrow or in the cells of the immune system. He explains his research and clinical goals.
NCCN Annual Congress on Hematologic Malignancies™ Returns to In-Person October 14–15, 2022 in New York City
The 2022 NCCN Annual Congress on Hematologic Malignancies™ (#NCCNhem22) is taking place Friday, October 14–Saturday, October 15, 2022 in New York City. All live sessions will also stream remotely through a virtual event platform.
CellaVision® launches a complete workflow solution for low-volume hematology laboratories
DIFF-Line™ by CellaVision is a new, comprehensive solution for small labs. It consists of three instruments for smearing, staining, and analyzing peripheral blood smears: CellaVision® DC-1, RAL® SmearBox, and RAL® StainBox.
Big Relief in a Small Pack
For patients in the Hematology-Adolescent Medicine Clinic at Children’s Hospital Los Angeles, the menstrual care products they take home after each visit are a source of comfort and relief—mentally, physically and financially. Every month in the United States, approximately 1 in 5 menstruating individuals leave school early or miss school entirely because they do not have access to menstrual care products.
Yaskawa’s AutoSorter XN Provides Pre- and Post-Analytic Specimen Processing for Sysmex XN-Series Line
Specifically designed to support the Sysmex® XN-Series hematology line, AutoSorter™ XN is a robust robotic platform for pre- and post- analytic specimen processing in demanding laboratory environments.
Caregivers for People with Multiple Myeloma Face Mental Health Challenges
Caregivers for patients with multiple myeloma may suffer from higher rates of anxiety and depression than patients themselves, according to a new study published today in Blood Advances.
New Blood: Lab-Grown Stem Cells Bode Well for Transplants, Aging Research
UC San Diego researchers develop a method to grow hematopoietic stem cells in culture, with clinical implications for bone marrow transplants and aging research.
Cardio-cerebrovascular disease history complicates hematopoietic cell transplant outcomes
Researchers find pre-transplant cardiovascular diseases indirectly affect mortality and survival through increased post-transplant disease occurrence
New method predicts COVID-19 severity, could help with hospital triage
During the height of the pandemic, some hospitals were overwhelmed with patients seeking treatment for COVID-19. This situation could happen again during future outbreaks, especially with SARS-CoV-2 variants of concern on the rise. Now, researchers reporting in ACS’ Analytical Chemistry…
New theory suggests blood immune and clotting components could contribute to psychosis
A scientific review has found evidence that a disruption in blood clotting and the first line immune system could be contributing factors in the development of psychosis. The article, a joint collaborative effort by researchers at RCSI University of Medicine…
Engineers find imaging technique could become treatment for deep vein thrombosis
Penn State College of Engineering researchers set out to develop technology capable of localizing and imaging blood clots in deep veins. Turns out their work may not only identify blood clots, but it may also be able to treat them.…
Red blood cell ‘traffic’ contributes to changes in brain oxygenation
Adequate blood flow supplies the brain with oxygen and nutrients, but the oxygenation tends to fluctuate in a distinct, consistent manner. The root of this varied activity, though, is poorly understood. Now, Penn State researchers have identified one cause of…
Early anticoagulant treatment shown to reduce death in moderately ill COVID-19 patients
International RAPID Trial could contribute to clinical practice
Sensing “junk” RNA after chemotherapy enhances blood regeneration
Hematopoietic stem cells take advantage of RNA from pathogenic remnants integrated in the genome to replenish the blood system
American Society for Radiation Oncology (ASTRO) to host Annual Meeting in Chicago 10/24-27
#ASTRO21 will be the first major medical conference in the city; a curated digital program also will be offered for remote attendees
Can leukemia in children with Down syndrome be prevented?
Princess Margaret Scientists reveal a new target that suggests it can
McMaster researchers identify how VITT happens
The work will have both diagnostic and therapeutic implications
Next generation cytogenetics is on its way
Does optical genome mapping turn cytogenetics upside down?
UCLA scientist honored for pioneering work in hematology research
LOS ANGELES – Dr. Elizabeta Nemeth, professor of medicine and director of the Center for Iron Disorders at the David Geffen School of Medicine at UCLA, has been awarded the 2021 William Dameshek Prize by the American Society of Hematology…
Study identifies risk factors for severe COVID-19 in individuals with sickle cell disease
Researchers urge high-risk patients to get COVID-19 vaccine
Knowledge of nurses for pain management of patients on maintenance hemodialysis
The article by Dr. Eman Khamis Al Nazly and Dr. Husam Al Khatib is published in the journal, The Open Nursing Journal
Repairing ‘broken’ hearts — new promising surgical technique for heart attacks
Medical researchers devise a new way to repair the ruptured wall of the heart from a severe heart attack
Thrombosis in cancer
Ever since the association between cancer and thrombosis was reported by Jean-Baptiste Bouillaud in the early 19th century, cancer-associated thrombosis has remained a challenging domain of cancer management. Thrombosis can at times be a lead to cancer diagnosis, while it…
Running in the blood: Blood lipids are linked to cancer, but depending on family history
Medical researchers identify the role of family history in the link between blood lipids and esophageal cancer
Microscopic CCTV reveals secrets of malaria invasion
State-of-the-art video microscopy has enabled researchers at WEHI, Australia, to see the molecular details of how malaria parasites invade red blood cells – a key step in the disease. The researchers used a custom-built lattice light sheet microscope – the…
Researchers identify why COVID-19 patients develop life-threatening clots
New insights could lead to new therapies for COVID-19
Free event will connect heart, lung, blood and sleep point-of-care inventors with resources
M2D2 program to feature NIH, Johnson & Johnson leaders
UC San Diego Health Begins Treating Multiple Myeloma with CAR T-cell Therapy
As the first designated medical center in San Diego certified to offer this type of immunotherapy, UC San Diego Health will begin treating patients this month.
Genetic base editing treats sickle cell disease in mice
Converting a pathogenic hemoglobin gene to a benign variant enables healthy blood cell production in an animal model of sickle cell disease
UC San Diego Health begins treating multiple myeloma with CAR T-cell therapy
Following the Food and Drug Administration’s approval, UC San Diego Health is the first designated medical center in San Diego certified to offer a new immunotherapy treatment of multiple myeloma outside of a clinical trial. The new immunotherapy is a…
Using advanced imaging to study sickle cell disease
Pitt’s Tamer Ibrahim uses recently optimized 7-Tesla MRI imaging technology to study SCD’s effect on the brain
Blood clot-busting nanocapsules could reduce existing treatment’s side effects
Tested on human blood in the lab, the selective nanocapsules could reduce the side effects of a major blood clot dissolving drug, which include bleeding on the brain. If confirmed with animal tests, the nanocapsules could also make the drug…
CHOP Researchers Develop Proof-of-Concept Treatment that Elevates Both Adult and Fetal Hemoglobin
Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and adult hemoglobin. Using a viral vector engineered to reactivate fetal hemoglobin production, suppress mutant hemoglobin, and supply functional adult hemoglobin, the researchers developed an approach that could produce more hemoglobin through a single vector. The results were published in Haematologica.
Researchers develop proof-of-concept treatment that elevates adult and fetal hemoglobin
CHOP study shows vector developed to treat blood disorders could simultaneously reactivate fetal hemoglobin, suppress mutant adult hemoglobin, and supply functional adult hemoglobin
Mini bone marrow model predicts response to blood disorder treatment
Scientists have described a miniature 3D bone marrow model that can both predict the response of patients to a new therapy for blood platelet disorders and facilitate studies to better understand these disorders
Innovative technologies to develop cancer and virus biomarkers
Politecnico di Torino’s ANFIBIO project will develop a set of technologies and advanced sensors to detect and quantify cancer and viral bio-markers in bodily fluids, making simpler, faster and more economical the diagnosis of many diseases