Sickle Cell Disease | sciencenewsnet.in

Gene therapy gives man with sickle cell disease the chance for a better future

November 30, 2020 sarah Jonas Gene Therapy, Sickle Cell Disease, Stem Cell Therapy, Stem Cells

In July 2019, Evie Junior enrolled in a clinical trial for an experimental stem cell gene therapy for sickle cell disease. The study is led by UCLA Broad Stem Cell Research Center physician-scientists Dr. Donald Kohn and Dr. Gary Schiller and funded by the California Institute for Regenerative Medicine.

Announcement

Intellia Therapeutics Receives Grant to Develop Curative CRISPR/Cas9 In Vivo Sickle Cell Disease Treatments

November 11, 2020 sarah Jonas Bill And Melinda Gates Foundation, Sickle Cell Disease

Intellia Therapeutics Receives Grant to Develop Curative CRISPR/Cas9 In Vivo Sickle Cell Disease Treatments

Feature

Lost in Transition: Sickle Cell Clinic Helps Adults Continue Care

September 29, 2020 sarah Jonas Disease Management, Genetics, Hematology, Sickle Cell Disease

Networking California for Sickle Cell Care Initiative supports expansion of San Diego’s only adult sickle cell disease clinic at UC San Diego Health which offers child-to-adult transition health services to patients like Vanessa Hughes.

Feature Expert

Understanding Sickle Cell Disease

September 25, 2020 sarah Jonas New Jersey, Rutgers Cancer Institute of New Jersey, Rutgers University, Sickle Cell Awareness Month, Sickle Cell Disease

Sickle cell disease is a lifelong inherited disorder of the red blood cells that poses many challenges for the people and families living with it. Rutgers Cancer Institute expert shares more on the basics of sickle cell disease and how the illness is managed.

Research Results

Gut Microbiome Translates Stress Into Sickle Cell Crises

July 30, 2020 sarah Jonas Cell Biology, gut microbiome, SCD, Sickle Cell Disease

A new study shows how chronic psychological stress leads to painful vessel-clogging episodes—the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible ways to prevent them. The research was conducted by scientists at Albert Einstein College of Medicine and published online today in Immunity.

Feature Expert

COVID-19: What you should know if you have sickle cell disease

July 7, 2020 sarah Jonas Coronavirus, COVID-19, Sickle Cell Disease

If you have sickle cell disease, you are at higher risk than the general population for severe complications from COVID-19.

Announcement

NIH announces $1 million prize competition to target global disease diagnostics

February 26, 2020 sarah Jonas Anemia, Bioengineering, Malaria, Sickle Cell Disease

The National Institutes of Health has launched a $1 million Technology Accelerator Challenge (TAC) to spur the design and development of non-invasive, handheld, digital technologies to detect, diagnose and guide therapies for diseases with high global and public health impact. The Challenge is focused on sickle cell disease, malaria and anemia and is led by NIH’s National Institute of Biomedical Imaging and Bioengineering (NIBIB).

Research Results

While Promoting Diseases Like Cancer, These Enzymes Also Cannibalize Each Other

January 20, 2020January 21, 2020 sarah Jonas 0 Comments atheroscleroisis, autodigestion, Breast Cancer, Breast Cancer Metastasis, Cancer, Cannibalization, Cathepsin, cathepsin K, cathepsin L, cathepsin S, cathepsins, Distracting, Protease, Protease Inhibitor, Protease Inhibitor Drugs, Sickle Cell Anemia, Sickle Cell Anemia Research, Sickle Cell Disease, Systems Biology

In diseases like cancer, atherosclerosis, and sickle cell anemia, cathepsins promote their propagation. Drug trials to inhibit these enzymes have failed due to baffling side effects. Now a new study examines cathepsins in systems to remove some of the bafflement.

Research Results

Yale Cancer Center researchers show identifying type of chronic pain in adults with sickle cell disease may lead to better outcomes

December 6, 2019 sarah Jonas 0 Comments Blood Cancers, Cancer, Oncology, Sickle Cell Disease, Smilow Cancer Hospital, YALE, Yale Cancer Center

Identifying the type of pain an adult with sickle cell disease (SCD) experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center (YCC) and Smilow Cancer Hospital.

Research Results

Likelihood of Prenatal Screening for Blood Disorders Varies Between Type of Healthcare Provider

December 5, 2019 sarah Jonas 0 Comments ASH annual meeting, Blood Disorders, hematologic malignancies, New Jersey, OB GYN, Rutgers University, Sickle Cell Anemia, Sickle Cell Disease

A Rutgers Cancer Institute of New Jersey investigator and other collaborators examined prenatal screening practices for blood disorders between different types of care providers and found different variations in prenatal guidance.