A prespecified secondary analysis of the MINT (Myocardial Ischemia and Transfusion) trial estimated the effect of 4 strategies to inform an optimal hemoglobin threshold for transfusion among anemic patients suffering from myocardial infarction (MI).
Tag: Anemia
JMIR Perioperative Medicine Invites Submissions on Perioperative Blood Management
JMIR Publications is pleased to announce a new theme issue titled “Perioperative Blood Management” in JMIR Perioperative Medicine.
Study suggests need for iron tests in teen girls & young women
A national study of blood ferritin and hemoglobin levels from tween, teen and young adult females suggests routine screening might be needed for iron deficiency and anemia.
Could low iron be making your mental health symptoms worse?
A review of the evidence regarding iron deficiency, iron supplementation, and mental health symptoms.
Targeted therapy momelotinib provides significant symptom and anemia improvements in patients with myelofibrosis
Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according to results from the international Phase III MOMENTUM trial led by researchers at The University of Texas MD Anderson Cancer Center.
How have changes in anemia care affected patients with kidney failure?
2011 changes in policies and recommendations related to the use of erythropoietin-stimulating agents were associated with lower hemoglobin levels and lower risks of major adverse cardiovascular events, mortality, and stroke among adults receiving hemodialysis, but with a higher risk of heart attack.
Penn Medicine Study Finds Red Blood Cells Play Much Larger Role in Immune System Through Discovery of DNA-Binding Capability
New research has revealed that red blood cells function as critical immune sensors by binding cell-free DNA, called nucleic acid, present in the body’s circulation during sepsis and COVID-19, and that this DNA-binding capability triggers their removal from circulation, driving inflammation and anemia during severe illness and playing a much larger role in the immune system than previously thought. Scientists have long known that red blood cells, which are essential in delivering oxygen throughout the body, also interacted with the immune system, but didn’t know whether they directly altered inflammation, until now. The study, led by researchers at the Perelman School of Medicine at the University of Pennsylvania, was published today in Science Translational Medicine.
Penn Medicine Study Finds Red Blood Cells Play Much Larger Role in Immune System Through Discovery of DNA-Binding Capability
New research has revealed that red blood cells function as critical immune sensors by binding cell-free DNA, called nucleic acid, present in the body’s circulation during sepsis and COVID-19, and that this DNA-binding capability triggers their removal from circulation, driving inflammation and anemia during severe illness and playing a much larger role in the immune system than previously thought. Scientists have long known that red blood cells, which are essential in delivering oxygen throughout the body, also interacted with the immune system, but didn’t know whether they directly altered inflammation, until now. The study, led by researchers at the Perelman School of Medicine at the University of Pennsylvania, was published today in Science Translational Medicine.
Patients with Kidney Disease—Even without Anemia—May Benefit From Iron Treatment
• Among individuals with chronic kidney disease, iron deficiency was linked with higher risks of death and cardiovascular events, in patients with and without anemia.
• Clinical trials are needed to test the effects of iron treatment, even in the absence of anemia, in patients with chronic kidney disease.
Anemia Discovery Points to More Effective Treatment Approaches
A combination of inexpensive oral medications may be able to treat fatigue-inducing anemias caused by chronic diseases and inflammation, a new discovery from the University of Virginia School of Medicine suggests.
Landmark Study Suggests Malaria-Preventive Drugs Dramatically Reduce Infections and Improve Health of School Children
Use of preventive antimalarial treatments reduces by half the number of malaria infections among schoolchildren, according to a new analysis published today in The Lancet Global Health.
Penn State College of Medicine study explores the association of malaria, HIV with anemia during pregnancy
Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections according to Penn State College of Medicine researchers. The findings may have implications for reducing the risk of death in pregnant women and preventing low birth weights and neurocognitive impairment in their children as a result of anemia.
High-altitude adaptations connected with lower risk for chronic diseases
High-altitude adaptations in the Himalayas may lower risk for some chronic diseases, according to a research team including faculty from Binghamton University, State University of New York, the University of New Mexico, and the Fudan University School of Life Sciences.
NIH announces $1 million prize competition to target global disease diagnostics
The National Institutes of Health has launched a $1 million Technology Accelerator Challenge (TAC) to spur the design and development of non-invasive, handheld, digital technologies to detect, diagnose and guide therapies for diseases with high global and public health impact. The Challenge is focused on sickle cell disease, malaria and anemia and is led by NIH’s National Institute of Biomedical Imaging and Bioengineering (NIBIB).