A research team led by the National University of Singapore has developed a smart wearable sensor that can conduct real-time, point-of-care assessment of chronic wounds wirelessly via an app. A world’s first, the novel sensor technology can detect temperature, pH, bacteria type and inflammatory factors specific to chronic wounds within 15 minutes, hence enabling fast and accurate wound assessment.
A multifaceted microfluidic in vitro assay is helping to identify the role of hypoxia on red blood cell aging via the biomechanical pathways. It holds promise for investigating hypoxic effects on the metastatic potential and relevant drug resistance of cancer cells.
Inspired by the way plants absorb and distribute water and nutrients, Lawrence Livermore National Laboratory researchers have developed a groundbreaking method for transporting liquids and gases using 3D-printed lattice design and capillary action phenomena.
Watching a viral infection happen in real time is like a cross between a zombie horror film, paint drying, and a Bollywood epic on repeat. Over a 10-hour span, chemical engineers from Michigan Tech watched viral infections happen with precision inside a microfluidics device and can measure when the infection cycle gets interrupted by an antiviral compound.
In a groundbreaking new study, researchers at the University of Minnesota, in collaboration with the U.S. Army Combat Capabilities Development Command Soldier Center, have 3D printed unique fluid channels at the micron scale that could automate production of diagnostics, sensors and assays used for a variety of medical tests and other applications. The team is the first to 3D print these structures on a curved surface, providing the initial step for someday printing them directly on the skin for real-time sensing of bodily fluids.
Microcapsules for the storage and delivery of substances are tiny versions of the type of capsule used for fish oil or other liquid supplements. A new method for synthesizing microcapsules, reported in AIP Advances, creates microcapsules with a liquid core that are ideal for the storage and delivery of oil-based materials in skin care products. They also show promise in some applications as tiny bioreactors. In this new method, a surfactant-free microfluidics process is used.
Blood can typically be stored for only six weeks after donation, but a potential solution attempts to dry blood by using a sugar-based preservative. New work in ultrasound technology looks to provide a path to inserting these sugars into human red blood cells, allowing the molecule trehalose to enter the cells and prevent their degradation when dried for preservation. The researchers discuss their work in this week’s Biomicrofluidics.
Infertility is estimated to affect 9% of reproductive-aged couples globally, and many couples turn to assisted reproductive technology. Selecting embryos with maximum development potential plays a pivotal role in obtaining the highest rate of success in ART treatment.
Researchers can evaluate the quality of an embryo by detecting the content of proteins secreted. In Biomicrofluidics, a method to detect trace proteins secreted by embryos using microfluidic droplets and multicolor fluorescence holds promise to select embryos for ART.
Researchers invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic and other conditions following a heart attack. The chip can be used to monitor electrophysiological and molecular response of the cells to heart attack conditions in real time.
With a recent publication in the journal Annals of Biomedical Engineering (ABME), a team of LLNL researchers are one step closer to recapitulating the brain’s response to both biochemical and mechanical cues in a chip-based platform.