World Heart Day is Sept. 29 – Heart rhythm disorders are one of the most common cardiac problems. Arrhythmias cause the heart to beat too fast, too slow, or irregularly. People can be born with them or develop them during their lives.
Receiving the diagnosis of a genetic heart disease such as long QT syndrome, which can cause sudden cardiac death, has long been a game-ender for young athletes. But a 20-year study at Mayo Clinic following such athletes who were allowed to return to play suggests that the risks can be managed through a shared decision-making process. The retrospective study findings will be presented at the annual meeting of the Heart Rhythm Society on Tuesday, July 27, and simultaneously published in the Journal of the American College of Cardiology.
Northwestern Medicine Bluhm Cardiovascular Institute recently became the first cardiovascular program in the United States to use the new VeriSight Pro ICE catheter during a cryoablation procedure to treat a heart arrhythmia.
In Biophysics Reviews, researchers provide an update on how electrical impulses in the heart travel from cell to cell. The connections between cells forming the low resistance pathway and facilitating the current flow are called gap junctions. Each consists of many channels, which are formed when specific proteins from one cell dock and fuse to the proteins from another cell. The scientists delve into the properties of gap junctions and their constituent proteins.
A new study in the Journal of the American Heart Association is the first to show that exposure to a stressful political election is strongly associated with an increase in potentially life-threatening cardiac events.
Article title: Functional coculture of sympathetic neurons and cardiomyocytes derived from human induced pluripotent stem cells Authors: Annika Winbo, Suganeya Ramanan, Emily Eugster, Stefan Jovinge, Jon R. Skinner, Johanna M. Montgomery From the authors: “We present data on a functional coculture between…
September is National Atrial Fibrillation Month, and Stephen L. Winters, MD, director of the Cardiac Rhythm Management Program, Gagnon Cardiovascular Institute, Atlantic Health System’s Morristown Medical Center, wants the public to know some surprising facts about this increasingly common heart condition.
The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for Covid-19, is known to have potentially serious effects on heart rhythms. Now, a team of researchers has used an optical mapping system to observe exactly how the drug creates serious disturbances in the electrical signals that govern heartbeat.
Researchers invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic and other conditions following a heart attack. The chip can be used to monitor electrophysiological and molecular response of the cells to heart attack conditions in real time.
Low oxygen levels in the heart have long been known to produce life-threatening arrhythmias, even sudden death. Until now, it was not clear how.
New findings, in a study led by Steve A. N. Goldstein, MD, PhD, vice chancellor for Health Affairs at the University of California, Irvine, and distinguished professor in the UCI School of Medicine Departments of Pediatrics and Physiology & Biophysics, reveal the underlying mechanism for this dangerous heart disorder.
At a glance:
Research using heart cells from squirrels, mice and people identifies an evolutionary mechanism critical for heart muscle function
Gene defect that affects a protein found in the heart muscle interferes with this mechanism to cause hypertrophic cardiomyopathy, a potentially fatal heart condition
Imbalance in the ratio of active and inactive protein disrupts heart muscle’s ability to contract and relax normally, interferes with heart muscle’s energy consumption
Treatment with a small-molecule drug restores proper contraction, energy consumption in human and rodent heart cells
If affirmed in subsequent studies, the results can inform therapies that could halt disease progression, help prevent common complications, including arrhythmias and heart failure