Sickle Cell Disease Continues to Face Underfunding, Lack of Research

Over the years, dedicated sickle cell disease programs and research initiatives have greatly improved patient care and life expectancy. But, giving these patients the care they require still presents a number of challenges, including inadequate funding for sickle cell programs, lack of research, and limited access to healthcare.

Ultrasound-Assisted Molecule Delivery Looks to Preserve Blood for Years

Blood can typically be stored for only six weeks after donation, but a potential solution attempts to dry blood by using a sugar-based preservative. New work in ultrasound technology looks to provide a path to inserting these sugars into human red blood cells, allowing the molecule trehalose to enter the cells and prevent their degradation when dried for preservation. The researchers discuss their work in this week’s Biomicrofluidics.

Blood Shortage on the Battlefield? Just Make It On-site

A new program launched by the Department of Defense could be the answer to blood shortages on the battlefield, other remote locations, and in hospitals. The Uniformed Services University of the Health Sciences’ 4D Bio3 On-Demand Blood Program, or 4D Bio3 Blood, has developed highly efficient protocols and technology to generate red blood cells from stem cells. A key part of this technology is large-scale cell expansion at low cost, producing sufficient red blood cells for treatment in trauma care. This technology is also being adapted to create neutrophils, ultimately allowing for whole blood transfusion using these methods in the future.