JMIR Formative Research | Digital Life Coaching During Stem Cell Transplantation

JMIR Publications recently published “Digital Life Coaching During Stem Cell Transplantation: Development and Usability Study” in JMIR Formative Research which reported that the authors launched a single-arm pilot study to investigate the feasibility of patient engagement with digital life coaching (DLC) during this intensive period.

Businesses selling non-FDA-approved stem cell products grew four-fold in five years, UCI study says

More than four times as many businesses and clinics than were identified in 2016 are selling stem cell products not approved by the U.S. Food and Drug Administration and lack convincing evidence of safety and efficacy, according to a five-year study conducted by University of California, Irvine Program in Public Health professor of health, society and behavior Leigh Turner. The analysis appears online in the journal Cell Stem Cell.

jCyte Inc. Identifies Retinitis Pigmentosa Patients Most Likely to Respond in Planned Pivotal Study with jCell Therapy

jCyte’s presentation at ARVO 2021, demonstrated that retinitis pigmentosa patients treated with the 6 million cell dose of jCell therapy had significant gains in a broad range of visual function tests – BCVA, visual field (KVF), contrast sensitivity (CS), and low luminance mobility (LLMT) – all which measure important and different aspects of functional vision. jCyte also engaged the Cleveland Clinic to identify an anatomical biomarker for patient response to jCell therapy in retinitis pigmentosa, which will help guide the upcoming pivotal study.

Audacious projects develop imaging technology to aid eye tissue regeneration

As regenerative therapies for blinding diseases move closer to clinical trials, the National Eye Institute’s functional imaging consortium, a part of the NEI Audacious Goals Initiative (AGI), is pioneering noninvasive technologies to monitor the function of the retina’s light-sensing neurons and their connections to the brain.

Mount Sinai Researchers Identify Mechanisms That Are Essential for Proper Skin Development

Mount Sinai researchers have discovered that Polycomb complexes, groups of proteins that maintain gene expression patterns, are essential for proper skin development, according to a paper published in Genes & Development on February 18.

Scientists Take Important Step Toward Using Retinal Cell Transplants to Treat Blindness

Retinal cells derived from a cadaver human eye survived when transplanted into the eyes of primate models, an important advance in the development of cell therapy to treat blindness, according to a study published on January 14 in Stem Cell Reports.

Stem Cell Therapy Helps Broken Hearts Heal in Unexpected Way

A study in Nature shows stem cell therapy helps hearts recover from a heart attack, although not for the biological reasons originally proposed two decades ago that today are the basis of ongoing clinical trials. The study reports that injecting living or even dead heart stem cells into the injured hearts of mice triggers an acute inflammatory process, which in turn generates a wound healing-like response to enhance the mechanical properties of the injured area.

Better Biosensor Technology Created for Stem Cells

A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer’s and Parkinson’s diseases and other neurological disorders. The technology, which features a unique graphene and gold-based platform and high-tech imaging, monitors the fate of stem cells by detecting genetic material (RNA) involved in turning such cells into brain cells (neurons), according to a study in the journal Nano Letters.