Using DNA-based assembly, the Center for Functional Nanomaterials postdoc has assembled functional proteins into ordered lattices and coated nanostructures for drug delivery.
Jin Kim Montclare, professor of chemical and biomolecular engineering led a team who previously reported a responsive hydrogel formed using a coiled-coil protein. The team expanded their studies to identify the gelation of Q protein at distinct temperatures and pH conditions.
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
A research team at the Fralin Biomedical Research Institute at VTC has identified the type of brain cell that produces a protein that is crucial for the formation of inhibitory circuits in the brain. This insight could one day help scientists establish the basis for developing new drugs that mature or repair cellular networks.
ORNL story tips: Air taxis, fungi speak, radiation game and climate collab
Spider silk is useful for a variety of biomedical applications: It exhibits mechanical properties superior to synthetic fibers for tissue engineering, and it is not toxic or harmful to living cells. One unexpected application for spider silk is its use in the creation of biocompatible lenses for biological imaging applications. Researchers describe the feasibility of creating lenses capitalizing on the properties of natural spider silk material in the Journal of Applied Physics.
Researchers combined gas foaming and 3D molding technologies to quickly transform electrospun membranes into complex 3D shapes for biomedical applications. The new approach demonstrates significant improvements in speed and quality compared with other methods, and is the first successful demonstration of formation of 3D neural tissue constructs with an ordered structure through differentiation of human neural progenitor/stem cells on these transformed 3D nanofiber scaffolds. They discuss their work in this week’s Applied Physics Reviews.
Rutgers engineers have created a highly effective way to paint complex 3D-printed objects, such as lightweight frames for aircraft and biomedical stents, that could save manufacturers time and money and provide new opportunities to create “smart skins” for printed parts. The findings are published in the journal ACS Applied Materials & Interfaces.
Ultrasound is probably most associated with a parent’s first glimpse of a baby in the womb. However, a new video from the Acoustical Society of America showcases the technology’s abilities to do more than show images of our insides. This video is the second in a series celebrating the International Year of Sound.
National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression. The findings, published online April 21 in Cell Reports, suggest that the epigenome could be targeted as a therapeutic strategy to prevent leading causes of vision loss, such as age-related macular degeneration (AMD).
Engineers at Binghamton University, State University of New York are stepping up on several fronts to help regional healthcare providers deal with the coronavirus pandemic.
Biohydrogels have been studied closely for their potential use in biomedical applications, but they often move between sols and gels, depending on their temperature, changes that can pose issues depending on the intended use. In Physics of Fluids, researchers discuss their work studying the effect of temperature on hydrogels. They found that creating hydrogels at room temperature or below results in more robust materials that function more effectively when used in the body.
Rutgers biomedical engineers have developed a “bio-ink” for 3D printed materials that could serve as scaffolds for growing human tissues to repair or replace damaged ones in the body. Their study was published in the journal Biointerphases.
In the future, robots could take blood samples, benefiting patients and healthcare workers alike. A Rutgers-led team has created a blood-sampling robot that performed as well or better than people, according to the first human clinical trial of an automated blood drawing and testing device.
With $4 million in matching funds from the National Institutes of Health, the University of Washington has created a new integrated center to match biomedical discoveries with the resources needed to bring innovative products to the public and improve health.
With a recent publication in the journal Annals of Biomedical Engineering (ABME), a team of LLNL researchers are one step closer to recapitulating the brain’s response to both biochemical and mechanical cues in a chip-based platform.
Researchers have developed a more efficient fabrication method for silk that allows them mold the material like plastic into solid forms for a wide range of applications, including medical devices. The properties of the end products can be “tuned”, and modified with bioactive molecules, such as antibiotics and enzymes.
Researchers at McMaster University have created a new coating to prevent clotting and infection in synthetic vascular grafts, while also accelerating the body’s own process for integrating the grafted vessels.
Rutgers engineers have embedded high performance electrical circuits inside 3D-printed plastics, which could lead to smaller and versatile drones and better-performing small satellites, biomedical implants and smart structures. They used pulses of high-energy light to fuse tiny silver wires, resulting in circuits that conduct 10 times more electricity than the state of the art, according to a study in the journal Additive Manufacturing. By increasing conductivity 10-fold, the engineers can reduce energy use, extend the life of devices and increase their performance.
The Nobel Prize in Physiology or Medicine and the Nobel Prize in Chemistry are awarded for the discoveries of major importance in life science, medicine or chemistry. Over 35 Nobel Laureates have been members of the ASCB at some time…