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Randomized Trial Reports Outcomes with Novel, Low Profile Fixed-Wire Drug-Eluting Stent that Facilitates Transradial Access

October 19, 2020 sarah Jonas Angioplasty, Cardiology, Heart Disease, Stents

The OPTIMIZE randomized trial comparing a novel, low-profile drug-eluting stent (DES) facilitating transradial access (TR) and direct stenting (DS) to existing DES did not establish non-inferiority of the new stent based on the prespecified study statistical analysis plan, likely due to the definition of periprocedural target vessel myocardial infarction (TVMI) coupled with a large proportion of high-sensitive cardiac troponin assays used in the trial.

Research Results

Randomized Clinical Trial Finds No Mortality Risk or Benefit Associated with Drug-Coated Devices in the Treatment of Peripheral Artery Disease

October 19, 2020 sarah Jonas Cardiology, Endovascular, interventional cardology, PAD, Stents

A large subgroup analysis of a randomized clinical trial showed neither a mortality risk nor benefit associated with the use of paclitaxel drug-coated devices (DCD) in the treatment of peripheral artery disease (PAD). The study also found that the benefit of rivaroxaban use on reducing ischemic limb and cardiovascular outcomes was consistent regardless of whether a DCD was used.

Research Results

Randomized Trial Comparing a Nano-Coated Coronary Stent and Shorter DAPT Did Not Meet Non-Inferiority Criteria for Thrombotic Events

October 19, 2020 sarah Jonas Angioplasty, Cardiology, DAPT, Heart Disease, Interventional Cardiology, Stenting, Stents

For patients undergoing percutaneous coronary intervention (PCI) that also require oral anticoagulation, treatment with a nanotechnology polymer-coated stent plus 14-day dual anti-platelet therapy (DAPT) did not reduce bleeding or establish non-inferior outcomes for thrombotic events compared with a drug-eluting stent (DES) and standard three or six-month DAPT therapy.

Research Results

Physiology-guided Percutaneous Coronary Intervention Optimization Strategy May Lead to Improved Outcomes

October 16, 2020 sarah Jonas Angioplasty, Cardiology, Heart Disease, Interventional Cardiology, PCI, Stents

Results from the randomized controlled TARGET FFR trial show that while a physiology-guided percutaneous coronary intervention (PCI) optimization strategy did not achieve a significant increase in the proportion of patients with final FFR ≥0.90, it reduced the proportion of patients with a residual FFR ≤0.80 following PCI.

Research Results

Meta-Analysis of Bivalirudin vs. Heparin in Patients with MI Examines Mortality and Bleeding Rates

October 14, 2020 sarah Jonas Angioplasty, Cardiology, Heart Disease, Interventional Cardiology, PCI, Stenting, Stents

An individual patient data pooled analysis comparing the use of bivalirudin versus heparin in heart attack patients undergoing percutaneous coronary intervention (PCI) found that bivalirudin use was associated with similar overall rates of 30-day mortality across all heart attack patients, but lower rates of serious bleeding events. Moreover, mortality was reduced in patients with ST-segment elevation myocardial infarction (STEMI) who were treated with a post-PCI bivalirudin infusion.

Announcement

TCT Connect Agenda Now Available

October 5, 2020 sarah Jonas Angioplasty, Cardiology, Cardiology and Covid-19, Coronary Artery Disease, Endovascular, Interventional Cardiology, PCI, Stents, structural heart disease, TAVR, TAVR heart team, TAVR procedure

The TCT Connect agenda is now available online. TCT, the annual scientific symposium of CRF and the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place online October 14-18. Every year, TCT features major medical research breakthroughs and gathers leading researchers and clinicians from around the globe to present and discuss the latest evidence-based research in the field.

Research Results

A Great New Way to Paint 3D-Printed Objects

April 28, 2020 sarah Jonas 3D printers, 3d printing, Biomedical, Chemistry, Electronics, Engineering, Environment, Health, Hydrogel, Manufacturers, Manufacturing, Medical, Nanoparticles, New Jersey, NJ, Paint, Painting, Printing, Quantum Dots, Robotics, Robots, Rutgers, Rutgers School of Engineering, Rutgers University-New Brunswck, soft robots, Solar Cells, Stents, Technology, Vaccines

Rutgers engineers have created a highly effective way to paint complex 3D-printed objects, such as lightweight frames for aircraft and biomedical stents, that could save manufacturers time and money and provide new opportunities to create “smart skins” for printed parts. The findings are published in the journal ACS Applied Materials & Interfaces.

Research Results

Robot Uses Artificial Intelligence and Imaging to Draw Blood

March 4, 2020 sarah Jonas Arteries, Artificial Intelligence, autonomous systems, Biomedical Engineering, Biotech, Blood, Blood Vessels, Device, Diagnostic, Drugs, Elderly, Engineering, Fluids, Health, Health Care, Imaging, Injuries, Medical, Medication, Medicine, Models, New Jersey, NJ, Patients, Pediatric, Pharmaceuticals, Robot, Robotics, Rutgers, Rutgers University-New Brunswick, Stents, Tech, Technology, Trauma, Ultrasound, Veins, Volunteers

Rutgers engineers have created a tabletop device that combines a robot, artificial intelligence and near-infrared and ultrasound imaging to draw blood or insert catheters to deliver fluids and drugs. Their research results, published in the journal Nature Machine Intelligence, suggest that autonomous systems like the image-guided robotic device could outperform people on some complex medical tasks.

Research Results

Ticagrelor Without Aspirin Three Months After Successful PCI and DAPT Reduces Major Bleeding Without Increasing the Risk of Adverse Events

September 26, 2019 sarah Jonas 0 Comments Angioplasty, antiplatelet therapy, Cardiology, DAPT, Dual antiplatelet therapy, Interventional Cardiology, PCI, Stents, ticagrelor

New data from the randomized, placebo-controlled TWILIGHT trial found that compared to ticagrelor plus aspirin, ticagrelor monotherapy reduces bleeding events without increasing the risk of death, myocardial infarction, or stroke in high-risk patients who have undergone successful percutaneous coronary intervention (PCI) and completed three months of dual antiplatelet therapy (DAPT).