MacNeal Hospital Launches First Clinical Trial in Illinois of Novel Monitoring Device for Congestive Heart Failure Patients

MacNeal Hospital is the first hospital in Illinois to participate in a national, randomized clinical trial using daily vital signs and lung pressure measurement to manage patients with congestive heart failure (CHF). The PROACTIVE-HF trial utilizes a new monitoring system, coupled with a pressure sensor, implanted directly into a blood vessel in the lung. This system provides information that is recorded and transmitted over a cellular or Wi-Fi connection to a patient’s provider, allowing for medication changes, if necessary, to prevent further health deterioration or hospitalization.

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Critical Transition Theory Shows Flickering in Heart Before Atrial Fibrillation

Atrial fibrillation ranks among the most common heart conditions, and episodes are difficult to predict. Researchers have proposed a way to define cardiac state and have studied the dynamics before the cardiac rhythm changes from normal sinus to AF rhythm and vice versa. The work, appearing in Chaos and based on critical transition theory, looks to provide an early warning for those with paroxysmal atrial fibrillation with potential implications for future wearable devices.

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Experimental cholesterol-lowering drug effective at lowering bad cholesterol, study shows

Twice-yearly injections of an experimental cholesterol-lowering drug, inclisiran, were effective at reducing low-density lipoprotein (LDL) cholesterol, often called bad cholesterol, in patients already taking the maximum dose of statin drugs, according to data of the ORION-10 trial presented Saturday, Nov. 16, at the American Heart Association’s Scientific Sessions 2019.

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Cyp2F2-Mediated Lung Cancer, Rapid Risk Assessment of Color Additives, and More Featured in November 2019 Toxicological Sciences

Toxicological Sciences continues to deliver cutting-edge research in toxicology in the November 2019 issue. This issue features research on computational toxicology and databases, developmental and reproductive toxicology, and more.

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