Researchers: Majority of patients with Alzheimer’s disease would not have been eligible for clinical trials of new controversial Alzheimer’s drug    

In a research letter in JAMA, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) found that the vast majority of patients who had a diagnosis of either cognitive impairment, Alzheimer’s disease, or Alzheimer’s disease related disorders, including cardiovascular disease, prior stroke, use of blood thinners, and age over 85 years, would have been excluded them from the aducanumab clinical trials.

Second Breath: Region’s First Double Lung Transplant for COVID-19 Patient

After more than 50 days on advanced life support, a multi-disciplinary team at UC San Diego Health helps a patient who contracted COVID-19 become a candidate for a successful double lung transplant. The transplant surgery was the first in the region performed on a COVID-19 patient.

Estudo da Mayo Clinic de 20 anos sugere que o retorno à prática esportiva é viável para atletas com a maioria das doenças cardíacas genéticas

Receber o diagnóstico de uma doença cardíaca genética, como a síndrome do QT longo, que pode causar morte súbita cardíaca, é considerado o fim de carreira para jovens atletas.

Estudio de Mayo Clinic durante 20 años plantea posibilidad de que deportistas con enfermedades cardíacas genéticas vuelvan al deporte

Desde hace mucho tiempo, los deportistas jóvenes se han visto obligados a poner fin a la práctica del deporte cuando se les diagnostica una enfermedad cardíaca genética, como síndrome del intervalo QT largo, afección capaz de ocasionar muerte cardíaca repentina.

Examining Correlation Between Occupational Noise, Heart Disease

Hearing conservation programs and policies aim to protect workers from noise-induced hearing loss, but it remains unclear whether stress reactions caused by noise exposure might also lead to other negative health outcomes. In The Journal of the Acoustical Society of America, researchers describe how data from the Canadian Health Measures Survey do not support an association between loud noise exposure and changes in biomarkers for cardiovascular disease or outcomes.

Bioprinted 3D Cardiac Patches Could Reverse Scar Formation, Promote Myocardial Regeneration After Heart Attacks

Myocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue. In APL Bioengineering, researchers take stock of stem cell-laden 3D-bioprinted cardiac patch technologies and their efficacy as a therapeutic and regenerative approach for ischemic cardiomyopathy in reversing scar formation and promoting myocardial regeneration. They explore types of candidate stem cells that possess cardiac regenerative potential and share updates on the challenging implementation of the state-of-the-art 3D-bioprinting approach.

A Mayo Clinic é pioneira no uso de diagnóstico por imagem ICE 4D de última geração para ajudar pacientes com doença cardíaca estrutural

Recentemente, a Mayo Clinic se tornou a primeira a usar um dispositivo de ecocardiograma intracardíaco (ICE) quadridimensional (4D) de última geração em pacientes para guiar cirurgias cardíacas como oclusão do apêndice atrial esquerdo, reparo da válvula mitral e tratamento de regurgitação da válvula tricúspide.

Mayo Clinic es la primera en usar imágenes de ecocardiograma intracardíaco cuadridimensional para ayudar a pacientes con enfermedades anatómicas del corazón

Mayo Clinic es la primera institución en utilizar un dispositivo de nueva generación para ecocardiograma intracardíaco (ICE, por sus siglas en inglés) cuadridimensional en los pacientes con el fin de guiar procedimientos cardíacos, como el cierre del apéndice auricular izquierdo, la reparación de la válvula mitral y el tratamiento de la regurgitación de la válvula tricúspide.

A Mayo Clinic Healthcare em Londres passa a oferecer também cardiologia, gastroenterologia e pneumologia

A Mayo Clinic Healthcare, uma clínica ambulatorial que oferece cuidados de saúde desde exames preventivos e planos de bem-estar personalizados até segundas opiniões sobre diagnósticos complexos, passa a oferecer também especialidades como cardiologia, gastroenterologia e pneumologia.

Mayo Clinic Healthcare en Londres añade cardiología, gastroenterología y neumología

Mayo Clinic Healthcare es una clínica de consulta externa que ofrece atención médica personalizada con detecciones preventivas, planes individualizados de bienestar y segundas opiniones para diagnósticos complejos que ahora añade varias especialidades médicas, entre ellas, cardiología, gastroenterología y neumología.

Study Compares Heart Benefits of Low-Fat and Plant-Centered Diets

There has been a long-standing debate as to whether a low-fat or a plant-centered diet is better at lowering the risk of cardiovascular disease. A new study that followed more than 4,700 people over 30 years, found that a plant-centered diet was associated with a lower long-term risk for cardiovascular disease. However, both diets were linked with lower LDL, or bad cholesterol, levels.

Metal Contamination, Gene Signatures, Bisphenol F, and More Featured in June 2021 Toxicological Sciences

Toxicological Sciences delivers the latest research in toxicology, in areas such as clinical and translational toxicology; emerging technologies, methods, and models; and environmental toxicology.

Estudo de ECGs que utiliza IA revela que a diferença entre a idade em anos e a idade biológica afeta significativamente a saúde e a longevidade

Você pode ser mais velho ou mais jovem do que pensa. Um novo estudo descobriu que as diferenças entre a idade de uma pessoa em anos e sua idade biológica, conforme previsto por um eletrocardiograma (ECG), habilitado para inteligência artificial (IA) podem fornecer percepções mensuráveis sobre saúde e longevidade.

Estudio de electrocardiogramas mediados por inteligencia artificial descubre que diferencia entre edad numérica y edad biológica afecta considerablemente la salud y la longevidad

Usted puede ser mayor o menor de lo que pensaba. Un nuevo estudio descubrió que las diferencias entre los años cumplidos por una persona y la edad biológica pronosticada por un electrocardiograma (ECG) mediado por inteligencia artificial puede aportar una perspectiva medible de la edad y la longevidad.

Gut Check

At a glance:

Researchers identify links between genetic makeup of bacteria in human gut and several human diseases

Clusters of bacterial genes present in conditions including cardiovascular illness, inflammatory bowel disease, liver cirrhosis, and cancer

Work brings scientist closer to developing tests that could predict disease risk or identify disease presence based on a sampling of the genetic makeup of a person’s microbiome

O filtro HEPA reduz as partículas respiratórias transportadas pelo ar geradas durante exercícios intensos

Aerossóis respiratórios são um componente comum da respiração e são uma forma comum de vírus respiratórios, como o COVID-19 , se espalharem para outras pessoas e superfícies. Os pesquisadores que realizam testes de esforço físico para pacientes cardíacos na Mayo Clinic descobriram que praticar exercícios em níveis crescentes de esforço aumentava a concentração de aerossol no ambiente ao redor. Eles também descobriram que um filtro de ar particulado de alta eficiência (HEPA) filtrou de forma eficaz os aerossóis e diminuiu o tempo necessário para limpar o ar entre os pacientes.

El filtro HEPA reduce las partículas respiratorias transmitidas por el aire que se generan durante el ejercicio intenso

Los aerosoles respiratorios son un componente común de la respiración y constituyen una vía común de propagación de virus respiratorios como la COVID-19 a personas y superficies. Los investigadores que realizan pruebas de esfuerzo físico en pacientes con problemas cardíacos en Mayo Clinic hallaron que el ejercicio a niveles mayores de esfuerzo aumentaba la concentración de aerosoles en el entorno circundante. Además, descubrieron que el filtro recogedor de partículas de alta eficiencia (HEPA, por sus siglas en inglés) descartaba de manera eficaz los aerosoles y disminuía el tiempo necesario para purificar el aire entre los pacientes.

Intensive Lifestyle Intervention Is Beneficial for Most People with Type 2 Diabetes, But Not All

For people who are overweight or obese and have type 2 diabetes, the first line of treatment is usually lifestyle intervention, including weight loss and increased physical activity. While this approach has cardiovascular benefit for many, it can be detrimental for people who have poor blood sugar control, according to a study conducted by researchers at Wake Forest School of Medicine.

Using Stimuli-Responsive Biomaterials to Understand Heart Development, Disease

The heart cannot regenerate new tissue, because cardiomyocytes, or heart muscle cells, do not divide after birth. However, researchers have now developed a shape memory polymer to grow cardiomyocytes. Raising the material’s temperature turned the polymer’s flat surface into nanowrinkles, which promoted cardiomyocyte alignment. The research is part of the growing field of mechanobiology, which investigates how physical forces between cells and changes in their mechanical properties contribute to development, cell differentiation, physiology, and disease.

Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk Factors in Health and Disease

A healthy lifestyle is composed primarily of regular structured physical activity (i.e., exercise). As a result, there is vast research into the clinical benefits of exercise, in most cases showing a better effect than drug interventions. Current physical activity guidelines…

Cardiac Calcium Scoring Saves One Man’s Life

The imaging procedure (called a CT Calcium Scoring scan) a CT or CAT scan, is a preventive cardiovascular screening test that is painless and noninvasive and takes only 10 minutes. Electron Beam Computed Tomography (EVCT) beam detects and measures the amount of calcium in the heart’s arteries. The more calcium that is present, the greater the likelihood of developing heart disease or having a heart attack or stroke. The test provides patients and their health care providers with the most accurate available “picture” of their current risk of developing heart disease or experiencing a heart attack.

Study Links Intensive Blood Pressure Lowering to Reduced Cardiovascular Risk in Patients Exposed to High Levels of Air Pollution

In a new study published this week in the journal Hypertension, researchers at University Hospitals (UH) and Case Western Reserve University (CWRU) School of Medicine found intensive BP lowering is effective in reducing cardiovascular risk in patients exposed to high levels of air pollution.

Lung, Heart, Kidney and Liver Transplant Programs Rank among Nation’s Best

UC San Diego Health’s lung, heart, kidney and liver transplant programs rank at the top nationally in the latest biannual Scientific Registry of Transplant Recipients (SRTR) report. Innovative treatment and multi-disciplinary care contribute to the high rankings for one-year survival outcomes.

Young survivors of acute myeloid leukemia have long-term complications from treatment

Adolescent and young adult (AYA) patients treated for acute myeloid leukemia (AML) have a high risk of developing several long-term health complications after treatment, a study led by UC Davis Comprehensive Cancer Center researchers has found. The most common complications were cardiovascular, endocrine and respiratory diseases. The complications – known as late effects – were more present among non-white AYA patients and those living in more deprived neighborhoods.

Children with Kawasaki Disease at Higher Risk for Heart Problems More Than 10 Years After They Leave the Hospital

New research shows that children with Kawasaki Disease remain at an increased risk for cardiovascular events more than 10 years after hospitalization for their condition, highlighting the need for long-term heart disease surveillance and risk reduction strategies for these young patients. Details of the study was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.

Global event: #BlackInCardio to celebrate Black excellence, raise awareness of cardiovascular diseases in the Black community

The first #BlackInCardio week happens Oct. 19-25. It’s an inclusive event with organizers from many institutions, welcoming everyone at all career levels and all career types to join in and inspire more Black students to consider a career in cardiovascular medicine/research.

Cleveland Clinic Study Identifies Weight-Loss Threshold for Cardiovascular and Survival Benefits in Patients with Obesity and Diabetes

A Cleveland Clinic study shows that 5 to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison, about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss. The study is published in the October issue of Annals of Surgery.

UC San Diego Health Revives Non-Beating Donor Heart for Successful Transplantation

UC San Diego Health is the first hospital on the West Coast to perform heart transplant surgery from a donor after circulatory death using a new portable organ care system. The investigational procedure could significantly decrease transplant waiting list times and improve patient outcomes.

Cholesterol-Lowering Drug Improved Function of Heart’s Arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

MedStar Washington Hospital Center Again Ranks Among Top U.S. Hospitals for Cardiovascular Care

MedStar Washington Hospital Center has again been recognized as one of the top 50 cardiovascular centers in the country. The Hospital Center’s Cardiology and Heart Surgery program moved up four spots from last year’s survey, to No. 37, in the 2020-21 U.S. News & World Report “Best Hospitals” rankings. It also received the highest rating possible in aortic valve surgery, congestive heart failure, heart bypass surgery, and transcatheter aortic valve replacement (TAVR).

Baylor Scott & White Health Again Recognized as Most Awarded Not-for-profit Health System in Texas by U.S. News & World Report

In the midst of the extraordinary health challenge presented by the COVID-19 pandemic, Baylor Scott & White Health remains committed to quality, safe care and helping Texas communities navigate the uncertainty of the SARS-CoV-2 virus. Today, this commitment to safety and quality is recognized as U.S. News & World Report releases its 2020-2021 Best Hospitals list.

UC San Diego Health Ranked #1 by U.S. News & World Report

UC San Diego Health is ranked first in San Diego and sixth in California, placing it among the nation’s best hospitals, according to the 2020-2021 U.S. News & World Report. Eight common procedures and conditions were also rated “high performing.”

Heart attack, stroke risk declines among people with diabetes

The rate of heart attacks, strokes and other cardiovascular complications has improved among people with diabetes over the past 20 years, narrowing the gap in cardiovascular mortality rates between individuals with and without diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.