Study shows how certain cancers neutralize T cells to subvert the immune system and help tumors grow
From March through December 2020, more than 16,000 cancer deaths were due to complications of COVID-19 in the United States, according to a new study led by researchers at the American Cancer Society.
An international team of scientists, co-led by researchers at the University of California San Diego School of Medicine, has created the first pan-cancer mycobiome atlas — a survey of 35 types of cancer and their associated fungi
Researchers at UCLA’s Jonsson Comprehensive Cancer Center and collaborating organizations report successful results from an experimental cancer-detection system that appears to have overcome some of the challenges of the “liquid biopsy” in a novel, cost-effective way.
One in eight women will be diagnosed with breast cancer in her lifetime. For those with BRCA1 and BRCA2 gene mutations, the chances are even higher. The National Breast Cancer Foundation estimates that 55 to 65% of women with the BRCA1 mutation, and 45%…
Sylvester Comprehensive Cancer Center researchers Lluis Morey, Ph.D., and Ramiro Verdun, Ph.D., have received a $1.8 million NIH R01 grant to study the epigenetic mechanisms that drive head and neck cancers.
Police officers and construction workers who responded on September 11, 2001, to the World Trade Center disaster in New York City and worked in its aftermath had at least twice the risk of developing the precursor for multiple myeloma compared…
The National Cancer Institute has awarded a five-year, $13.3 million grant to a collaborative study on sequential combinations of targeted inhibitors and immunotherapies against cancer.
Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).
Researchers at UC San Diego have used artificial intelligence-guided tools to pinpoint both a specific type of immune cell as the driver of esophageal cancer and a specific genetic variation that acts as a protective factor in African Americans.
Analysis from Rutgers connects many chronic conditions besides cancer and diabetes with medical debt.
A Ludwig Cancer Research study has identified a combination of three existing drugs that significantly extends survival in mouse models of the lethal brain cancer glioblastoma multiforme (GBM).
Researchers in China have discovered that inhibiting a protein called the GABAA receptor can protect intestinal stem cells from the toxic effects of chemotherapy and radiotherapy. The study, published September 20 in the Journal of Experimental Medicine (JEM), suggests that the FDA-approved anti-sedative flumazenil, which targets GABAA receptors, could alleviate some of the common gastrointestinal side effects, such as diarrhea and vomiting, induced by many cancer treatments.
UC San Diego Health now offers a novel therapy option shown to extend the lifespan and improve quality of life for certain patients.
Van Andel Institute’s Biorepository has been awarded a $7.9 million, five-year contract from the National Cancer Institute (NCI), part of the National Institutes of Health, to continue serving as the biorepository for the Cancer MoonshotSM Biobank study. The Institute has served as the Cancer MoonshotSM Biobank Biorepository since 2020, when it was awarded a two-year subcontract to develop the framework and protocols for this part of the initiative.
A novel clinical trial from Cedars-Sinai Cancer shows that active surveillance is an effective treatment for many low-risk thyroid cancer patients. The study, published in JAMA Oncology, also showed for the first time that patients who opted for active surveillance experienced less anxiety than patients who underwent surgery.
In a large study led by researchers at the American Cancer Society, men and women who drank two or more servings of sugar-sweetened beverages (SSB) per day, compared to people who never drank, had a five percent increased risk of death from an obesity-related cancer, including gastrointestinal, postmenopausal breast, endometrial and kidney cancer.
A new, large study led by researchers at the American Cancer Society and The University of Texas MD Anderson Cancer Center shows rising costs of cancer treatments led to increases in total costs of care, and when compounded with greater cost sharing, increased out-of-pocket costs for privately insured, patients under 65 years old.
En un estudio multinacional dirigido por un equipo de investigación de Mayo Clinic que empleó la inteligencia artificial, los investigadores desarrollaron un algoritmo para predecir mejor la recurrencia del cáncer colorrectal. Los resultados del estudio se publicaron en Gastroenterología.
Em um estudo multinacional liderado por uma equipe de pesquisa da Mayo Clinic usando inteligência artificial (IA), os pesquisadores desenvolveram um algoritmo para melhorar a previsão de recorrência de câncer colorretal.
Chicago-based Rush University System for Health and Franciscan Alliance, Inc., are partnering to jointly develop and provide clinical services to improve the availability of health care to patients in Northwest Indiana, giving patients streamlined access to subspecialty care in their own communities.
A new study by UT Southwestern’s Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer. The finding, published in Nature Communications, could eventually be used to develop new strategies to augment the anti-tumor effect of cancer immunotherapies, the study authors said.
A team led by University of Minnesota Twin Cities biomedical engineers has developed a universally accessible application that can simulate complex molecular interactions, which will allow researchers to design better treatments for diseases like cancer and COVID-19.
Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus — a finding that could lead to improved cancer diagnosis and treatment.
Muitas pessoas já experimentaram o desconforto de ter alimentos ou bebidas descendo acidentalmente pelo lugar errado ao engolir. Entretanto, problemas para engolir muitas vezes se tornam crônicos e podem ser um sinal de alguma doença que precisa ser tratada.
Researchers have launched a groundbreaking study utilizing autologous muscle derived progenitor cells to increase tongue strength for patients struggling with difficulty swallowing, many of whom are cancer survivors.
Alejandro Mirazo de 56 años nunca imaginó que los resultados de una prueba genética revelarían una vinculación hereditaria con el cáncer, ni que este descubrimiento podría salvarle la vida.
Studies suggest that Insulin-Like Growth Factor (IGF) plays a central role in pathological growth of proliferative conditions like cancer, and may function as a resistance mechanism adopted by the majority of solid cancers following therapeutic targeting of non-IGF signaling pathways.
Muchas personas experimentan la incomodad de que un alimento o bebida se vaya accidentalmente por el lugar equivocado durante la deglución. Sin embargo, los problemas de deglución a veces se vuelven crónicos y pueden ser la señal de una enfermedad que debería tratarse.
The pilot study is one of the first to indicate that neurofeedback could help address cognitive deficits of cancer patients experiencing “chemo brain.”
Miami, Fla. – September 11, 2001, changed America, and today we are learning more about the long-term health impacts of unprecedented environmental exposure to carcinogens at the World Trade Center disaster site. New research suggests that emergency response and recovery…
Many people have experienced the discomfort of food or a beverage accidentally going to the wrong place when swallowing. But swallowing issues sometimes become chronic and may be a sign of a health condition that should be treated.
Sylvester Comprehensive Cancer Center researcher Emmanuel Thomas, M.D., Ph.D., F.A.A.S.L.D., has been appointed to the National Institutes of Health’s (NIH) Coinfections and HIV Associated Cancers (HCAC) study section.
Henry Ford Health + Michigan State University Health Sciences today announced its funding of five cancer research grants of up to $100,000 each. These five grants follow an initial wave of funding from the partnership, in which 18 pilot grants of up to $25,000 each were funded in May 2022.
Un estudio dirigido por los científicos del Centro Oncológico Integral de Mayo Clinic descubrió que la adición de brentuximab vedotina a la quimioterapia estándar mejora la supervivencia general de los pacientes con linfoma de Hodgkin, comparado con la administración de solo la quimioterapia estándar.
Um estudo conduzido por pesquisadores do Centro de Câncer da Mayo Clinic descobriu que adicionar o brentuximab vedotina ao tratamento quimioterápico padrão aumenta a taxa geral de sobrevida de pacientes com linfoma de Hodgkin, em comparação com o padrão de tratamento atual que usa somente a quimioterapia.
A modified tuberculosis (TB) vaccine developed at Texas Biomed could help treat a form of bladder cancer, called non-muscle invasive bladder cancer, without strong side effects. Results in mouse models and human cells show promising results and pave the way for human clinical trials. The research, conducted in close collaboration with UT Health San Antonio, was published online in June in the journal Cancer Immunology, Immunotherapy.
Recent research indicates that during the first year of the COVID-19 pandemic, the proportion of working-aged U.S. adults without health insurance did not change despite increases in unemployment, and the prevalence of unhealthy behaviors decreased.
Cancer Council SA-funded researcher Associate Professor Stephanie Reuter Lange from UniSA hopes that a simple computer program can help personalise treatment for cancer patients.
In the latest Current Clinical Pathology publication on Immunotherapy, Sbarro Health Research Organization (SHRO) President, Antonio Giordano, M.D., Ph.D., co-edits the volume, focused on cardiovascular toxicities.
Kimberly Leslie, MD, was awarded a four-year, $1.8 million grant from the Department of Defense (DOD) to further study high-risk uterine cancer. Her research has led her to study the differences between natural progesterone and synthetic progestins – hormones often used for birth control – and the influence of progesterone on a tumor suppressor protein called p53. The hormones, drugs and proteins, she’s learned, influence each other and the body’s cells in complex ways.
Using UT Southwestern’s Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation. The findings, reported in Nature, shed light on the mechanisms behind this activity and could eventually lead to new drugs to treat various malignancies.
Researchers at the Georgia Institute of Technology have found a detection method that could revolutionize cancer treatment by showing how cancers metastasize and what stage they are.
A new study published by University of Kentucky Markey Cancer Center researchers suggests that the common steroid betamethasone could be used to reduce unwanted side effects of radiation treatments for prostate cancer.
New method uses nanospheres to measure forces that cancer cells use to spread through tissue
In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression. Their research also reveals how disruption of the circadian clock impacts genome stability and mutations that can further drive critical tumor promoting pathways in the intestine.
Lung disease caused by a new drug for cancers—including metastatic or advanced breast cancer—can be effectively treated using approaches that focus on early detection and prompt management, according to a study published in ESMO Open on August 11, 2022.
The laboratory of Hai-Hui “Howard” Xue at the CDI published the findings of the complex and cascading molecular interactions modulating T-cell immunology in the August issue of the journal Nature Immunology.
For tens of thousands of Australians who receive radiotherapy as part of their cancer treatment, mucositis is a serious side effect that may cause inflammation, ulcers, diarrhoea, nausea and vomiting, abdominal pain and bloating. Currently there is no effective treatment for mucositis, but researchers from the University of Adelaide have found that a type of traditional Chinese medicine reduces the severity of radiation-induced gastrointestinal mucositis (GIM) in rats.
A new study led by researchers at the American Cancer Society reports nearly 123,000 cancer deaths, or close to 30 percent of all cancer deaths, were from cigarette smoking in the United States in 2019, leading to more than two million Person-Years of Lost Life (PYLL) and nearly $21 billion in annual lost earnings. These losses were disproportionately higher in states with weaker tobacco control policies in the South and Midwest. The results were published today in the International Journal of Cancer.