Race, ethnicity, and poverty linked to worse outcomes in children treated for high-risk neuroblastoma

Children with high-risk neuroblastoma had worse outcomes if they were from certain racial/ethnic groups or were on public rather than private insurance, despite being treated in clinical trials with standardized protocols, according to a study led by investigators from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.

MD Anderson Research Highlights: ASCO 2022 Special Edition

This special edition features upcoming oral presentations by MD Anderson researchers at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting focused on quality improvement, health services research, new treatments for skin cancers, and symptoms and survivorship advances. More information on ASCO content from MD Anderson can be found at MDAnderson.org/ASCO.

Cancer and mental health: Mayo Clinic expert dispels myths

Everyone with cancer experiences it differently and all emotions are valid and important, regardless of the mix or intensity. Shawna Ehlers, Ph.D., a Mayo Clinic psychologist and psycho-oncology expert, helps patients cope with the burden of their cancer diagnosis. That includes dispelling myths that stress in their lives caused their cancer or that depression must be suffered through during cancer treatment.

A nanoparticle and inhibitor trigger the immune system, outsmarting brain cancer

Scientists at the University of Michigan fabricated a nanoparticle to deliver an inhibitor to brain tumor in mouse models, where the drug successfully turned on the immune system to eliminate the cancer. The process also triggered immune memory so that a reintroduced tumor was eliminated—a sign that this potential new approach could not only treat brain tumors but prevent or delay recurrences.

Scientists Discover Gene Plays Critical Role in Embryo Development

A new study co-led by a Cedars-Sinai investigator identified a gene that plays an important role in a biological pathway involved in embryo development. The gene’s impact at the cellular level could explain why some babies are born with physical abnormalities and why some adults develop diseases such as cancer. The findings are published in Nature Communications.

Sidekick Microbubbles Carry Anti-Cancer Drugs, Damage Tumor Vessels #ASA182

Naomi Matsuura, of the University of Toronto, and her team are adapting microbubbles to become more potent tools for cancer therapy. By shrinking the bubbles and directly loading them with anti-cancer drugs, the bubbles can lower the dose of free drug that is injected and diffuses into nontumor tissue in the body. This results in more targeted treatment and fewer side effects for the patient. Matsuura will discuss her team’s results in her presentation, “Ultrasound-stimulated, drug-loaded bubbles for cancer therapy,” as part of the 182nd Meeting of the Acoustical Society of America at the Sheraton Denver Downtown Hotel. The session will take place May 24 at 11:30 a.m. Eastern U.S.

DeepGI AI – A Thai Innovation for the Precision in Colorectal Polyp Detection

Chula Engineering and Chula Medicine co-invent an innovative device for a rapid gastrointestinal cancer detection that yields accurate results hoping to foster preventive medicine in gastrointestinal malignancy and reduce the number of cancer patients.

Scientists Find Sea Corals are Source of Sought After “Anti-Cancer” Compound

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer. Now, researchers at University of Utah Health report that easy-to-find soft corals make the elusive compound.

Exploring Cancer and Health Data on Asian American and Pacific Islanders

Cancer health disparities are often identified from population-based surveillance data routinely captured by statewide cancer registries. Antoinette Stroup, PhD, of Rutgers Cancer Institute of New Jersey, New Jersey’s only National Cancer Institute – Designated Comprehensive Cancer Center together with RWJBarnabas Health and Rutgers School of Public Health is the director of the New Jersey State Cancer Registry (NJSCR), explores cancer and health data on the Asian American and Pacific Islander population.

Penn Medicine Study Reveals Imaging Approach with Potential to Detect Lung Cancer Earlier, at the Cellular Level

Researchers at the Abramson Cancer Center at the University of Pennsylvania have found a way to identify lung cancer at the cellular level in real time during a biopsy, offering promise in the ability to detect the disease earlier and with more confidence. The research is published this week in Nature Communications.

New Study Finds Medicaid Expansion Increases Survival in Newly Diagnosed Cancer Patients

A new large study led by researchers at the American Cancer Society (ACS) shows Medicaid expansion under the Affordable Care Act (ACA) was associated with an increase in two-year overall survival rates among patients newly diagnosed with cancer, especially among non-Hispanic Black people and people living in rural areas.

Groundbreaking for Major Expansion of University of Maryland Greenebaum Comprehensive Cancer Center

The University of Maryland Medical Center celebrates the groundbreaking of a nine-story patient care tower – the Roslyn and Leonard Stoler Center for Advanced Medicine – that will become the new home of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center. The $219 million building will enable the cancer center to provide the most technologically advanced, integrated care to cancer patients throughout Maryland and the region well into the future

Researchers seek to improve success of chimeric antigen receptor-T cell therapy in non-Hodgkin lymphoma

A study published by researchers from Mayo Clinic Cancer Center at Mayo Clinic in Florida and Case Western, Cleveland Medical Center, investigates the reasons for decreasing remission rates for patients with non-Hodgkin lymphoma treated with chimeric antigen receptor-T cell therapy (CAR-T cell therapy).

Delays in surgery for advanced esophageal cancer result in significantly worse survival than early surgery

Delays in surgery for esophageal cancer did not appear to have much impact on patients’ relative survival for early-stage cancer compared with patients who had surgery early, but they did reduce the relative survival rate by almost half for patients with more advanced disease.

New Study Reports Need to Monitor Public Interest in Shopping and Sales of Popular Puff Bar E-cigarette Brand

New research led by scientists at the American Cancer Society shows the need for continued surveillance of the changes in shopping interest and sales for Puff Bar, the most preferred brand of electronic cigarettes or e-cigarettes among youth in the United States. Public interest in shopping and sales of Puff Bar skyrocketed in 2020.

Smoking-cessation program that targets cancer patients effective

Researchers at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis have found a way to help more patients who want to stop smoking. The successful strategy involves using electronic medical records to help identify smokers when they visit their oncologists and offering help with quitting during such visits.

Discovery of cell protein that keeps Kaposi’s sarcoma herpesvirus dormant

A study led by UC Davis Cancer Center identified a binding protein in cancer cell’s nucleus, known as CHD4, as a critical agent keeping Kaposi’s sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body’s immune system. CHD4 is linked to cancer cell growth in many types of cancers.

Descoberta da Mayo Clinic sobre câncer de medula óssea aponta para possíveis alvos de medicamentos

Uma nova pesquisa do Centro de Medicina Individualizada da Mayo Clinic descobre que pacientes com leucemia mielomonocítica crônica com mutação ASXL1 (um tipo incomum de câncer de medula óssea) têm alterações epigenéticas específicas que podem ativar genes nocivos e fazer com que o câncer cresça mais rapidamente.

Henry Ford Health First in Michigan to Offer Robotic High-Intensity Focused Ultrasound for Prostate Cancer

Henry Ford Health is the first in Michigan to offer Robotic High Intensity Focused Ultrasound (HIFU) for the treatment of localized prostate cancer. This non-surgical treatment option spares surrounding healthy tissue, while allowing for a quicker treatment time and recovery for the patient.

Drugs showing promise in cancer trials reduce scarring for scleroderma, study shows

Epigenetic drugs that have shown promise in cancer trials significantly reduce scarring in the cells of patients with scleroderma, a new study shows. Results reveal that drugs that inhibit BRD4, known to play a role in cancer, also affect fibrosis in scleroderma. Researchers tested BRD4 inhibitors on the skin fibroblasts of scleroderma patients and in mouse models of skin fibrosis, finding that the treatment stopped scarring in both human-derived cells and in animals.

Câncer colorretal aumenta em adultos jovens: especialista da Mayo Clinic explica os fatores de risco

As taxas de câncer colorretal em pessoas com menos de 50 anos estão aumentando ao redor do mundo. Jeremy Jones, M.D., oncologista da Mayo Clinic em Jacksonville, Flórida, descreve os fatores de risco que as pessoas podem evitar e os sinais de alerta que devem ser levados a sério em qualquer idade.

Patients with past cancer history not associated with higher risk of COVID-19-related death or hospitalization

Patients diagnosed with cancer more than one year ago and those not receiving active treatment were no more vulnerable to worse COVID-19 outcomes than patients without cancer, according to a new study led by UTHealth Houston.

Public Beware: Study Finds Potential for Massive Cancer Nutrition Misinformation on Pinterest

A multi-center team including researchers from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine claims that the social media site Pinterest is rife with cancer misinformation. Their study found that about a third of posts…

Pesquisadores da Mayo Clinic carregam células CAR-T com vírus oncolítico para tratar tumores sólidos

Pesquisadores do Centro de Medicina Individualizada da Mayo Clinic criaram uma técnica de imunoterapia que combina terapia de células T com receptor de antígeno quimérico, ou terapia celular CAR-T, com um vírus que mata o câncer para direcionar melhor o alvo e tratar com mais eficiência tumores de câncer sólidos.

Investigadores de Mayo Clinic llenan con virus oncolítico a células T con receptor de antígeno quimérico para tratar cáncer de tumor sólido

Los investigadores del Centro para Medicina Personalizada en Mayo Clinic inventaron una técnica de inmunoterapia que combina la terapia de células T con receptor de antígeno quimérico (CAR-T, por sus siglas en inglés) con un virus que elimina el cáncer a fin de apuntar de forma más eficiente el tratamiento contra el cáncer de tumor sólido.

Harrington Discovery Institute Announces 2022 Grant Funding to 11 Physician-Scientists

Harrington Discovery Institute at University Hospitals in Cleveland, Ohio, today announced the 2022 class of Harrington Scholar-Innovators. The scholar awards will support a diverse set of drug discovery projects including new treatments for pulmonary diseases, COVID-19, multiple cancers, corneal disease, hepatitis, and acquired spinal cord injuries.