Gene Expression | sciencenewsnet.in

Some types of prostate cancer may not be as aggressive as originally thought

June 4, 2020 sarah Jonas Gene Expression, prostate cancer

Researchers at the UCLA Jonsson Comprehensive Cancer Center analyzed gene-expression patterns in the most aggressive prostate cancer grade group — known as Gleason grade group 5 — and found that this grade of cancer can actually be subdivided into four subtypes with distinct differences. The findings may affect how people are treated for the disease.

Research Results

Impaired Immunity, Gene Expression May Explain Higher COVID-19 Risk in People with Diabetes

April 7, 2020 sarah Jonas Coronavirus, COVID – 19, Diabetes, Gene Expression, Immunity, Physiology

The behavior of previous coronaviruses together with physiological characteristics of diabetes may help explain why people with diabetes have a higher risk of developing COVID-19, a respiratory disease caused by the novel coronavirus SARS-CoV-2.

Research Results

Stress during Pregnancy May Negatively Affect Baby’s Muscles

March 12, 2020March 13, 2020 sarah Jonas Cortisol, Gene Expression, Heart Health, Muscles, Physiology, Pregnancy, Stress

Research in sheep suggests that high levels of a stress hormone during pregnancy may alter gene expression in multiple muscle groups of offspring. These shifts may affect heart, breathing and skeletal muscle function, and could potentially increase risks of inflammation and infection. The study is published ahead of print in Physiological Genomics.

Research Results

Surprise discovery shakes up our understanding of gene expression

January 22, 2020 sarah Jonas 0 Comments BIOCHEMISTRY, Biology, Cancer, Chromatin, DNA, fundamental biology, Gene Expression, genes, Methylation, RNA, University Of Chicago

A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality. Rather than directions going one-way from DNA to RNA to proteins, the latest study shows that RNA itself modulates how DNA is transcribed—using a chemical process that is increasingly apparent to be vital to biology. The discovery has significant implications for our understanding of human disease and drug design.

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Technique shows how individual cancer cells react to drugs

December 6, 2019 sarah Jonas 0 Comments Cell Biology, Drug Discovery, Gene Expression, Genome Sciences, Precision Medicine, RNA

A new technique reported in Science offers more detail, at the single cell level, on how large, pooled samples of various cells react to drugs or other agents. The data might reveal mode of action or the effect of genetic differences in varying responses.

Research Results

Complex Cellular Machine Visualized to Yield New Insights in Cancer

October 31, 2019 sarah Jonas 0 Comments Cancer, Gene Expression

Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein machine, elucidating how the RSC complex works and what role it has in healthy and cancer cells.

Research Results