Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.
Tag: Gene Regulation
Rewriting the Textbook on Gene Regulation: It’s the Big Picture That Counts
For the first time, researchers at UC San Diego have shown that changes in gene expression happen almost entirely during the transcription stage while the cells are growing. The researchers have provided a simple quantitative formula linking regulatory control to mRNA and protein levels.
Plant hormones to help prevent Striga invasion
As part of a multipronged approach to prevent infestations by the parasitic plant Striga hermonthica, researchers are unravelling the role of plant hormones, known as strigolactones (SLs).
Evidence for new theory of genetic recombination
In most higher organisms, including humans, every cell carries two versions of each gene, which are referred to as alleles.
3D map reveals DNA organization within human retina cells
National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell’s nucleus. The resulting comprehensive gene regulatory network provides insights into regulation of gene expression in general, and in retinal function, in both rare and common eye diseases. The study published in Nature Communications.
New sleep molecule discovered: “It shows just how complex the machinery of sleep is”
When brain scientist Birgitte Kornum from the Department of Neuroscience recently arrived in Rome for one of the largest sleep conferences in the world, she was completely taken aback.
Pinpointing where single-stranded transcripts converted into double-stranded RNAs
St. Jude scientist Vibhor Mishra, Ph.D., is homing in on the location where important processes in gene regulation occur, and where single-stranded transcripts are converted into double-stranded RNAs (dsRNAs).
Machine learning algorithm predicts how genes are regulated in individual cells
Researchers have developed a software tool that identify the regulators of genes. The system leverages a machine learning algorithm to predict which transcription factors are most likely to be active in individual cells.
New 3D maps reveal inner workings of immune cell gene expression
The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. Researchers have created 3D maps of how enhancer sequences and genes interact in several types of immune cells. Their new study opens the door to understanding individual risk for diseases from asthma to cancer.