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UrduNational Eye Institute researchers studying human retinas discovered 87 target genes where a mix of environmental factors likely influence one’s risk of developing age-related macular degeneration (AMD), a leading cause of vision loss in people ages 65 and older.
Tag: AMD
Inflammation-reducing drug shows no benefit for dry age-related macular degeneration in NIH trial
The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health.
UC Davis Eye Center tests experimental gene therapy for wet age-related macular degeneration (AMD)
Ophthalmologists at UC Davis Health used an experimental gene therapy last month to treat a patient with wet age-related macular degeneration, or wet AMD. Wet AMD is a leading cause of vision loss among older adults. Glenn Yiu, a professor of ophthalmology at UC Davis Health, is the principal investigator for the new clinical trial.
Research to Prevent Blindness and Association of University Professors of Ophthalmology Announce 2024 Recipient of RPB David F. Weeks Award for Outstanding Vision Research
Patricia Ann D’Amore, PhD, MBA, has been selected as the 2024 RPB David F. Weeks Award for Outstanding Vision Research (Weeks Award). Dr. D’Amore will receive her award and deliver a presentation during the AUPO 2024 Annual Meeting in Austin, Texas in February.
Early Frontier users seize exascale advantage, grapple with grand scientific challenges
With the world’s first exascale supercomputing system now open to full user operations, research teams are harnessing Frontier’s power and speed to tackle some of the most challenging problems in modern science.The HPE Cray EX system at the Department of Energy’s Oak Ridge National Laboratory debuted in May 2022 as the fastest computer on the planet and first machine to break the exascale barrier at 1.
Vision Research Funding Partnership Event Takes Place Today
Today, Research to Prevent Blindness (RPB) and more than 30 other organizations are convening in Washington DC for the Vision Research Funding Partnership event, which was organized around the theme of “The Research Pipeline – From Premise to Patient.”
AI-based systems can help identify rapidly advancing age-related macular degeneration
Researchers supported by the National Eye Institute are developing artificial intelligence/machine learning (AI/ML)-based systems that not only screen for AMD but also predict which patients will likely progress to late within two years. The systems also evaluate separately one’s risk for developing late wet (neovascular) AMD from one’s risk for late dry (geographic atrophy) AMD.
The American Macular Degeneration Foundation Premieres New Films During AMD Awareness Month 2023
The American Macular Degeneration Foundation will be hosting
multiple, awareness-spreading activities throughout February, which is AMD Awareness Month, including new films on living well with AMD.
ARVO Foundation Announces 2023 Bert M. Glaser, MD Award for Innovative Retina Research Recipient
Rockville, Md.—The Association for Research in Vision and Ophthalmology (ARVO) Foundation congratulates Miguel Flores-Bellver, PhD, recipient of the 2023 Bert M. Glaser, MD Award for Innovative Research in Retina. The award recognizes an early-career investigator who has made a novel discovery that impacted the understanding and/or treatment of a retinal disease or condition.
Combining multiple maps reveal new genetic risk factors for blindness
Researchers discover new clues for causes of adult-onset macular degeneration.
Mount Sinai Researchers First to Identify That Two Separate Eye Diseases May Contribute to Common Blinding Eye Condition
Two separate eye diseases may contribute to age-related macular degeneration (AMD), a leading cause of blindness in the United States, according to a new study from New York Eye and Ear Infirmary of Mount Sinai.
The American Macular Degeneration Foundation Drives Research and Hope With New Grants
The foundation is investing $1.1 million in studies that hold the potential to set new standards in the prevention and treatment of age-related macular degeneration
Research to Prevent Blindness Marks $400 Million in Funding to Advance Eye Disease Research
Research to Prevent Blindness announces a new round of awardees who are generating critical knowledge around a host of sight-threatening conditions. With this latest round of funding, RPB has provided more than $400 million in research funding.
3D map reveals DNA organization within human retina cells
National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell’s nucleus. The resulting comprehensive gene regulatory network provides insights into regulation of gene expression in general, and in retinal function, in both rare and common eye diseases. The study published in Nature Communications.
Blinding Eye Disease Is Strongly Associated With Heart Disease and Stroke
Patients with a specific form of age-related macular degeneration (AMD), a leading cause of blindness in the United States, are at significant risk for cardiovascular disease and stroke, according to new research from New York Eye and Ear Infirmary of Mount Sinai.
National Eye Institute launches data portal for macular degeneration research
The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2). The database complements newly available stem cell lines created by the New York Stem Cell Foundation Research Institute (NYSCF) from blood cells of AREDS2 study participants.
Age-related Macular Degeneration: Poised for a New Treatment Era
The American Academy of Ophthalmology is highlighting what the next decade may hold for the 11 million Americans suffering from AMD.
‘Expanse’ Supercomputer Formally Enters Production
The San Diego Supercomputer Center (SDSC) at UC San Diego announced that its new Expanse supercomputer formally entered service for researchers following a program review by the National Science Foundation (NSF), which awarded SDSC a grant in mid-2019 to build the innovative system.
Artificial Intelligence Algorithm Can Rapidly Detect Severity of Common Blinding Eye Disease
A new artificial intelligence (AI) algorithm developed by researchers at New York Eye and Ear Infirmary of Mount Sinai (NYEE) can rapidly and accurately detect age-related macular degeneration (AMD), a leading cause of vision loss in the United States.
Upgrades for LLNL supercomputer from AMD, Penguin Computing aid COVID-19 research
To assist in the COVID-19 research effort, Lawrence Livermore National Laboratory, Penguin Computing and AMD have reached an agreement to upgrade the Lab’s unclassified, Penguin Computing-built Corona high performance computing (HPC) cluster with an in-kind contribution of cutting-edge AMD Instinct™ accelerators, expected to nearly double the peak performance of the machine.
NEI researchers link age-related DNA modifications to susceptibility to eye disease
National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression. The findings, published online April 21 in Cell Reports, suggest that the epigenome could be targeted as a therapeutic strategy to prevent leading causes of vision loss, such as age-related macular degeneration (AMD).
Coronavirus and Your Macular Degeneration Care
Answers from trusted sources regarding macular degeneration care during the COVID-19 outbreak.
NIH researchers discover tooth-enamel protein in eyes with dry AMD
A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a study from researchers at the National Eye Institute (NEI).
Your Brain May be Disguising a Blinding Eye Disease
During February, the American Academy of Ophthalmology is urging people to protect themselves from vision loss from AMD by getting a baseline eye exam by age 40.
Potential Way to Halt Blinding Macular Degeneration Identified
It would be the first treatment for “dry” age-related macular degeneration and could significantly improve treatment for wet AMD.
Research to Prevent Blindness and Association of University Professors of Ophthalmology Announce 2019 Recipient of RPB David F. Weeks Award for Outstanding AMD Research
Christine Curcio, PhD, has been selected as the 2019 RPB David F. Weeks Award for Outstanding AMD Research (Weeks Award). The Weeks Award, funded through the generosity of Research to Prevent Blindness (RPB), an anonymous donor, and the Association of University Professors of Ophthalmology (AUPO), annually recognizes and celebrates an excellent researcher focused on age-related macular degeneration (AMD).