Closer to human — Mouse model more accurately reproduces fatty liver disease
Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver
Read morePHARMACEUTICAL SCIENCES
Mapping the paradigm shift of China’s cancer burden for designing prevention strategies
Researchers decode the recent statistics of the changing profiles of cancer incidence and mortality worldwide and in China to tailor control measures
Read moreToward a reliable oral treatment for sickle cell disease
WASHINGTON, April 9, 2021 — For the millions of people worldwide who have sickle cell disease, there are only a
Read moreNew formulation of existing medicines prove highly effective against drug-resistant fungus
CLEVELAND–A team of researchers from Case Western Reserve University has discovered a formulation of existing medicines that can significantly reduce
Read moreStructural biology opens new perspectives for treating psychiatric disorders
Scientists have determined the structure of Glycine Transporter 1; the finding could open new avenues for developing therapeutics for psychiatric disorders
Read moreACP best practice advice: Shorter course of antibiotics may be appropriate for some common infection
Embargoed news from Annals of Internal Medicine
Read moreMassive X-ray screening identifies promising candidates for COVID drugs
DESY’s X-ray lightsource PETRA III reveals existing active substances binding to key virus protein
Read moreThe first non-invasive biomarker to track and verify efficacy of senolytic drugs
The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases
Read moreSLAS Technology April issue dives into reactive oxygen species
Oak Brook, IL – The April edition of SLAS Technology features the cover article “Therapeutic Potential of Reactive Oxygen Species:
Read moreStem cell transplants prevent relapses of most common childhood cancer
Children and young adults who receive CAR T-cell therapy for the most common childhood cancer – acute lymphoblastic leukemia –
Read moreMt. Sinai Health Care Foundation awards $1 million grant to CWRU School o
The Mt. Sinai Health Care Foundation–continuing Mt. Sinai Medical Center’s century-old tradition of caring for Northeast Ohio–has expanded its commitment
Read moreRepurposing tocilizumab in scleroderma patients may prevent early lung disease
A phase 3 clinical trial finds an anti-inflammatory drug used in rheumatoid arthritis can preserve lung function in patients with systemic sclerosis.
Read moreTargeted opioid that hones in on inflamed tissues stops colitis pain without side effects
Study in mice points to promising treatment for pain in inflammatory bowel disease
Read morePumping the ‘brain brake’ in pediatric anxiety
UC researchers find ways to predict treatment outcomes for adolescent anxiety using brain imaging
Read moreNovel pharmacological strategies to treat alcoholism. Focus on epigenetics
This article by Dr. F. David Rodriguez is published in the journal, Current Pharmaceutical Design, 2021
Read moreHouston Methodist among largest providers of monoclonal antibody treatment for COVID-19
Strategy for successful mAB treatment program published in New England Journal of Medicine
Read more10,000-plus medical charts provides comparator for HIV prevention study in pregnant women
Records review conducted in four African countries published in PLOS ONE will help determine safety of PrEP and dapivirine ring in DELIVER; includes data seldom collected in these countries
Read moreNew $6.4M research program to advance psychedelics research and treatments
Psychedelics research in support of brain health is getting a major boost this month with the formation of the Neuroscape
Read more$2.5M award to fund joint organoid research program at Wake Forest Baptist Health
WINSTON-SALEM, NC – March 30, 2021 – Personalized medicine research for aggressive abdominal cancers at Wake Forest Baptist Health received
Read moreBespoke neuroblastoma therapy weaponizes cell metabolism
New mouse study shows that combining a new drug with an old one could exploit the insatiable “hunger” of a deadly childhood cancer
Read moreContact lenses poised to detect cancer, treat disease and replace digital screens
Newly-published “contact lens technologies of the future” paper reviews innovative uses for disease detection and therapy, drug delivery, vision enhancement and mor
Read moreFDA approvals strengthen Octapharma USA pediatric critical care product portfolio
Octaplas™ and fibryga® receive new product labeling following FDA’s approval of BLA supplements to update therapy research; FDA expands fibryga® indication to include treatment of children under 12 years of age
Read moreThe role of benzothiazole analogs in the treatment of tuberculosis
Tuberculosis is a serious infectious disease, which is caused by the Mycobacterium tuberculosis, generally it affects the lungs. Tuberculosis is
Read moreInflammation-fighting protein could improve treatment of rheumatoid arthritis
SPOKANE, Wash. – New research led by scientists at Washington State University has found that a protein known as GBP5
Read moreRelationship between psoriasis treatments and cardiovascular risk explained
New review shows available psoriasis treatments differ in terms of how they affect a patient’s likelihood of experiencing adverse cardiovascular events
Read moreBrazilian researchers obtain more efficient red bioluminescence
Luciferin-luciferase system developed in collaboration with Japanese researchers produces brighter and longer-lasting far red light. The innovation can be used to image cells and tissues for diagnosis and biomedical research.
Read moreExperimental antibodies for Parkinson’s, Alzheimer’s may cause harmful inflammation
Scientists find evidence that antibody-based treatments in clinical trials for neurodegenerative diseases may trigger an inflammatory response in human brain immune cells, eroding their positive effects.
Read moreCorrecting altered brain circuit could tackle coinciding obesity and depression
Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand.
Read moreNew approach against Covid-19
If Professor Thomas Rudel and the biopharmaceutical company Aeterna Zentaris GmbH have their way, there could possibly be significant enhancement
Read moreInsights on operationalizing COVID-19 monoclonal antibody treatment
PITTSBURGH, March 26, 2021 – As evidence mounts supporting the use of monoclonal antibody treatment to reduce hospitalizations and deaths
Read moreResearchers use machine learning to rank cancer drugs in order of efficacy
Researchers from Queen Mary University of London have developed a machine learning algorithm that ranks drugs based on their efficacy in reducing cancer cell growth
Read moreCommon Alzheimer’s treatment linked to slower cognitive decline
Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer’s disease, but their effects on cognition have
Read moreCholesterol may be key to new therapies for Alzheimer’s disease, diabetes
A unique approach to tackling these two diseases has allowed Dr. Gregory Thatcher to look beyond traditional causes to find novel therapies
Read moreC-Path launches acute kidney injury project with support from FDA
Project aims to develop improved predictive and detection tools for kidney injury
Read moreSecond drug targeting KRASG12C shows benefit in mutated non-small-cell lung cancer
ELCC 2021, 25-27 March
Read moreThree common antiviral drugs potentially effective against COVID-19
An international team of researchers has found that three commonly used antiviral and antimalarial drugs are effective in vitro at
Read moreNew cancer immunotherapy recruits help from lymphatic vessels
CHICAGO — Immunotherapy, which recruits the body’s own immune system to attack cancer, has given many cancer patients a new
Read moreNew drug candidate against COVID-19
SARS-CoV-2, the virus responsible for the COVID-19 pandemic, arrived one year ago and turned our lives upside-down. While worldwide vaccination
Read moreNanoparticle flu vaccine blocks seasonal and pandemic strains
Scientists at UW Medicine and the NIH have created experimental flu shots that spur broad immunity in animal trials.
Read moreRedHill announces compassionate use treatment with opaganib of Swiss COVID-19 patients
RedHill Biopharma Ltd. (Nasdaq: RDHL) today announced that it has acted on a request to provide opaganib treatment on an outpatient basis under compassionate use exemption for several Swiss patients suffering from COVID-19 pneumonia
Read moreChildren’s Hosp Colorado & STAQ Pharma develop solution to pediatric medication challenges
New partnership and product development optimizes patient care while addressing drug shortages and medical waste
Read moreViagra may prolong life for men with coronary artery disease
Men with stable coronary artery disease who are on Viagra due to impotence seem to live longer and have a
Read moreAntibody injections could become more affordable with new production method
Antibody injections are a highly desirable treatment for people with chronic diseases such as cancer, psoriasis, Crohn’s disease and arthritis.
Read moreUniform drying time for goldenseal to enhance medicinal qualities of forest herb
Developing a standardized drying protocol for goldenseal could lead to more predictable health applications and outcomes by preserving the alkaloids
Read moreAnti-tuberculosis drug can be safely dosed even higher
Publication in European Respiratory Journal
Read moreFocusing on the unhealthy brain to speed drug discovery
University of Houston collaboration with National Institutes of Health delivers toolkit to accelerate process
Read moreCombination thyroid hormone therapies treat hypothyroidism as well as levothyroxine
Treatment should be individualized for common thyroid condition, researchers say
Read moreImportant advance in research on future drugs
Most drugs operate via the membranes that surround the body’s cells. A study by researchers at Karolinska Institutet in Sweden
Read moreLSU Veterinary School receives $11M COBRE grant for a pre-clinical cancer research center
The Louisiana State University School of Veterinary Medicine, or LSU SVM, has received an $11 million grant to establish a
Read moreStarving tumors by blocking glutamine uptake
LA JOLLA, CALIF. – March 19, 2021 – Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug
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