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UrduPatients with obesity or type 2 diabetes are at a higher risk of developing NAFLD and NASH.
Tag: Internal Medicine
Advantages of intranasal vaccination against SARS-CoV-2
Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract
MRI, clear cell likelihood score correlate with renal mass growth rate
Standardized non-invasive clear cell likelihood score–derived from MRI–correlates with the growth rate of small renal masses and may help guide personalized management
ASMBS Foundation awards research grants for studies related to COVID-19 & obesity
Newberry, FL – July19, 2021– The American Society for Metabolic and Bariatric Surgery (ASMBS) Foundation today announced it has awarded two research grants totaling $50,000 to study the effects of obesity on COVID-19 infections in adolescents and the increasing use…
Less-sensitive COVID-19 tests may still achieve optimal results if enough people tested
Analysis suggests same epidemiological outcomes possible with rapid-antigen versus RT-PCR tests
Pathogens get comfy in designer goo
Rice, Baylor labs use custom hydrogels to mimic insides of intestines, study infectious bacteria
Researchers reverse emphysema in mice by injecting blood vessel wall cells
Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells–the cells that line the walls of blood vessels in the lung–can reverse the symptoms of emphysema. The study, which will be…
Toxicity testing on the placenta and embryo
Drugs must be safe not just for the patients; in the case of pregnant patients, drugs must also be safe for the unborn children still in the womb. Therefore, at an early stage in the development of new medicines, candidate…
Coffee Doesn’t Raise Your Risk for Heart Rhythm Problems
In the largest study of its kind, an investigation by UC San Francisco has found no evidence that moderate coffee consumption can cause cardiac arrhythmia.
Copper transporter potential new treatment target for cardiovascular disease
An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow…
Coffee doesn’t raise your risk for heart rhythm problems
UCSF Cardiology researchers report no link between coffee consumption and arrhythmia
Most studies of acute kidney injury are flawed due to non-use of standard definitions
In an article published in the American Journal of Kidney Diseases (AJKD), researchers found that among 176 studies on acute kidney injury, the Kidney Disease Improving Global Outcomes (KDIGO) definitions of kidney injury were inconsistently applied and 80% of studies…
Risk score with 6 routinely available lab tests accurately predicts kidney failure
Researchers developed a new risk equation, based on six routinely available patient parameters, that yielded improved performance in estimating the risk of a chronic kidney disease (CKD) patient to progress to end-stage kidney disease (ESKD) requiring kidney replacement therapy (KRT).…
For concussion patients, CTs offer window into recovery
UCSF-led study matches brain imaging with prognosis, showing lingering impairment for some
A small molecule induces readthrough of cystic fibrosis CFTR nonsense mutations
This research suggests that a path to treat currently untreatable cases of cystic fibrosis is clearly achievable.
Rapid screening, face masks may prevent SARS-CoV-2 transmission at indoor mass-gathering events
Embargoed News from Annals of Internal Medicine
Coffee and heart beats
What The Study Did: The association between daily coffee consumption and the risk of cardiac arrhythmias was evaluated in this study. Authors: Gregory M. Marcus, M.D., M.A.S., of the University of California, San Francisco, is the corresponding author. To access…
Disparities in outpatient visit rates
What The Study Did: Researchers examined racial/ethnic disparities in outpatient visit rates to 29 physician specialties in the United States. Authors: Christopher Cai, M.D., of the Internal Medicine Residency Program at Brigham and Women’s Hospital/Harvard Medical School in Boston, is…
Examining association between cycling, risk of death among people with diabetes
What The Study Did: This study investigated the association between time spent cycling and the risk of death from cardiovascular disease or any other cause among people with diabetes. Authors: Mathias Ried-Larsen, Ph.D., of Rigshospitalet in Copenhagen, is the corresponding…
Novel autoantibody adds fuel to COVID-19 ‘firestorm’ of inflammation, blood clots
The finding will likely help physicians develop targeted therapies for future COVID patients
Common COVID-19 antibiotic no more effective than placebo
UCSF outpatient study found limited effect of azithromycin on progression of disease
New guidance on how to diagnosis and manage osteoporosis in chronic kidney disease
Patients with advanced chronic kidney disease (CKD) typically suffer from impaired bone quality and quantity, with a non-vertebral fracture risk which is 4-to 6-fold higher than the fracture risk of matched controls. However, despite their high risk of fragility fractures,…
Study shows diet causes 84% drop in troublesome menopausal symptoms–without drugs
WASHINGTON–A new study, published by the North American Menopause Society in the journal Menopause, found a plant-based diet rich in soy reduces moderate-to-severe hot flashes by 84%, from nearly five per day to fewer than one per day. During the…
Inadequate sequencing of SARS-CoV-2 variants impedes global response to COVID-19
Better international sequencing efforts are needed to track and respond to new SARS-CoV-2 variants
New spray could someday help heal damage after a heart attack
Heart attack, or myocardial infarction, is one of the leading causes of death worldwide. Although modern surgical techniques, diagnostics and medications have greatly improved early survival from these events, many patients struggle with the long-term effects of permanently damaged tissue,…
Melanoma of the eye: Preclinical tests show path toward treatment
A small molecule inhibitor has been identified that reduces the growth of uveal melanoma, a rare and deadly cancer of the eye
Short chain fatty acids: An ‘ace in the hole’ against SARS-CoV-2 infection
Scientists find that short chain fatty acids can be used to reduce susceptibility to SARS-CoV-2 infection and mortality from COVID-19
Scientists identify new gut-liver drug recycling process
Implications for developing treatments for intestinal diseases
New research aims to improve treatments and outcomes for people with severe asthma
PrecISE study is now enrolling local patients and will use personalized medicine approach to test multiple therapies to treat severe asthma
Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality
Study suggests spatial relationship between COVID-19 mortality and population-level health factors
Keeping the world up to date on irritable bowel syndrome research in China
Scientists condense Chinese studies over the past decade on this common gastrointestinal disorder in a review article
Neither remdesivir nor HCQ affect viral clearance in hospitalized patients with COVID-19
Embargoed news from Annals of Internal Medicine
Reduced vs. standard CT dose for lung nodules in children, young adults with cancer
Reduced-dose CT depicts greater than 90% of lung nodules in children and young adults with cancer, identifying the presence of nodules with moderate sensitivity and high specificity
The ethics of split liver transplantation: Analyzing case studies to make the right decision
Split liver transplantation (SLT) provides an opportunity to divide a donor liver and offer transplants to two small patients, one or both of whom could be a child. SLT, which is underused in the United States, could be used more…
Researchers examine burden of electronic health record on primary care clinicians
Findings highlight streamlining opportunities allowing for general internal medicine and family medicine clinicians to have more time to interact with patients and families
Stroke treatment may backfire when kidneys don’t work well
Researchers at the National Cerebral and Cardiovascular Center in Japan show that excessive blood pressure reduction for acute intracerebral hemorrhage is risky in people with decreased kidney function Suita, Japan — Stroke and chronic kidney disease are both difficult to…
Precision medicine helps identify “at-risk rapid decliners” in early-stage kidney disease
A novel therapeutic may halt rapid kidney function in some type 1 diabetic kidney disease patients.
Scientists find liver drug candidates among pesticides
Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies — among pest control chemicals.…
Mucus and mucins may become the medicine of the future
Many people instinctively associate mucus with something disgusting, but in fact, it has incredibly many valuable functions for our health. It keeps track of our important intestinal flora and feeds the bacteria. It covers all internal surfaces of our body,…
Comparing spending on common generic drugs by Medicare vs Costco members
What The Study Did: The amount Medicare pays for common generic prescriptions in Part D was compared with prices available to patients without insurance at Costco. Authors: Erin Trish, Ph.D., of the University of Southern California, Los Angeles, is the…
Diabetes care, glycemic control during pandemic in US
What The Study Did: R ates at which patients with type 2 diabetes received diabetes-related health services prior to and during the COVID-19 pandemic are compared in this study. Authors: Ateev Mehrotra, M.D., M.P.H., of Harvard Medical School in Boston,…
Adult ADHD is linked to numerous physical conditions
Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry . “Identifying…
New nanotech will enable a ‘healthy’ electric current production inside the human body
The innovative material that creates green energy through mechanical force
Missing bile ducts offer clues to mechanism of liver injury
PITTSBURGH, July 6, 2021 – Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice. But despite…
New study uncovers how a series of sleep loss impacts mental and physical wellbeing
TAMPA, Fla. (July 6, 2021) – All it takes is three consecutive nights of sleep loss to cause your mental and physical well-being to greatly deteriorate. A new study published in Annals of Behavioral Medicine looked at the consequences of…
Infusion centers associated with substantially better outcomes than the ER for patients with acute pain events and sickle cell disease
Embargoed news from Annals of Internal Medicine
ACC Asia conference delivers emerging trends for improving heart health
Partnering with the Singapore Cardiac Society, ACC Asia 2021 moves into era of global collaboration in cardiovascular prevention and care
New clinical indicators discovered in transplant patients with COVID-19
Elisa Cordero, a doctor at the Virgen del Rocío University Hospital, researcher at the Institute of Biomedicine of Seville (IBiS) and professor in the Department of Medicine at the University of Seville, led a study involving researchers from 12 Spanish…
Plastic drapes reduce hypothermia in premature babies
Study: Plastic better than cloth for low birth-weight newborns
ACC, Wondr Medical to create new digital educational channel enabling interactive learning opportunities for global cardiovascular community
Channel will provide access to world-class content, support for under-supported audiences