$1.3 million in NIH grants to enable research into antibody-mediated drug delivery technology

Two National Institute of Health (NIH) grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences, is the Principal Investigator on both grants — $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.

Teens who use cannabis frequently more likely to have premature baby, study suggests

Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new University of Bristol-led study. The research, published in Scientific Reports, repeatedly assessed 665 participants in a general population cohort on their tobacco and cannabis use between ages 14 to 29 years, before pregnancy.

Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery

‘Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery’ gives the present status and future perspective of Polymeric nanoparticles, Liposomes, Carbon Nanotubes, Magnetic Nanoparticles, Silica Based nanomaterial, Hydrogels, Metallic Nanoparticles, Cyclodextrins, Poly (Lactide-Co-Glycolide) and its Copolymers. Improvement of a vector for…

UCI-led meta-analysis identifies hypertension medications that help ward off memory loss

Irvine, Calif., June  21, 2021 — A large-scale meta-analysis led by University of California, Irvine researchers provides the strongest evidence yet of which blood pressure medications help slow memory loss in older adults: those that can travel out of blood vessels and directly into the brain. The findings, published in the American Heart Association journal Hypertension, will be of interest to the 91 million Americans whose blood pressure is high enough to warrant medication, as well as the doctors who treat them.

Are social, behavioral risk factors associated with mortality among us veterans with COVID-19?

What The Study Did: An observational study of more than 27,000 veterans who received a positive test result for COVID-19 reports that risk factors such as housing problems, financial hardship, alcohol use, tobacco use and substance use weren’t associated with…

Pain monitoring helps assess the effectiveness of opioid-sparing approaches during surgery

A new study has shown that effective opioid-sparing anaesthesia with dexmedetomidine can be guided with NOL pain monitoring technology (Medasense, Israel). The study showed that the NOL monitor is able to detect the effect of dexmedetomidine on the patient’s pain…

Efforts to treat COVID-19 patients chronicled in UC Health medications data

Irvine, Calif., May 21, 2021 – A record of medicine utilization patterns assembled by an interdisciplinary team of researchers at the University of California, Irvine and the UC San Diego School of Medicine reveals the thought, care and scientific rigor clinicians at UC Health medical centers applied in their treatment of patients with COVID-19 in 2020.

Nearly 3% of Americans take immune-weakening drugs that may limit COVID vaccine response

A study of more than 3 million insured U.S. adult patients under 65 found that nearly 3% take immunosuppressive drugs that may elevate risk for severe COVID-19 symptoms and hospitalization if they became infected. There is growing evidence that immunosuppressive drugs may also reduce the COVID vaccine’s efficacy.

Conn. medication-assisted opioid treatment programs retain patients at higher rates

Medication-assisted treatment, or MAT, is an important tool in the ongoing fight against opioid use dependence in the United States. Employing certain medications in combination with counseling and behavioral therapy, MAT offers a comprehensive, “whole-patient” approach to addressing opioid use.…

Substance use, physical activity by adolescent before, during COVID-19 pandemic

What The Study Did: C hanges in adolescents’ use of e-cigarettes, cannabis and alcohol and in physical activity behaviors following the COVID-19 stay-at-home order in California are examined in this study. Authors: Benjamin W. Chaffee, D.D.S., M.P.H., Ph.D., of the…

Researchers identify a psychedelic-like drug without the hallucinogenic side effects

Psychedelic drugs have shown promise for treating neuropsychiatric disorders such as depression and posttraumatic stress disorder. However, due to their hallucinatory side effects, some researchers are trying to identify drugs that could offer the benefits of psychedelics without causing hallucinations.…

Johns Hopkins Medicine Expert Creates Comprehensive Guide to New Diabetes Drugs

New medicines for people who have diabetes seem to pop up all the time. Drugs that help the body break down carbohydrates, drugs that increase excretion of glucose in the urine, drugs that help muscles respond to insulin and drugs that stimulate the pancreas to produce it — the list of pharmaceutical options to treat diabetes gets longer and longer.

New $6.4M research program to advance psychedelics research and treatments

Psychedelics research in support of brain health is getting a major boost this month with the formation of the Neuroscape Psychedelics Division at the University of California, San Francisco (UCSF). Through $6.4M in private funding, the new division will take…

Family ties protect against opioid misuse among U.S. young adults

Syracuse, N.Y. – As opioid use disorders and overdoses continue to skyrocket in the United States, a study by researchers from Syracuse University and Pennsylvania State University shows that unmarried young adults who do not have children are mostly likely…

Evaluating state marijuana laws, rates of self-harm, assault

What The Study Did: Researchers examined whether state medical and recreational cannabis laws were associated with changes in rates of self-harm and assault injuries. Authors: Keith Humphreys, Ph.D., of Stanford University in Stanford, California, is the corresponding author. To access…