RUDN University doctors demonstrated the capabilities of a new method for remote analysis of drugs in packaging and after entering the body. They can be assessed using radio thermal emission of nanoparticles in drugs. Scientists were able to check the suitability of the medicine without opening the packaging or monitor it inside the body.
Tag: Drugs
New model identifies drugs that shouldn’t be taken together
Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.
Scientists discover hidden army of lung flu fighters
Scientists have long thought of the fluid-filled sac around our lungs merely as a cushion from external damage.
Unveiling the hidden power for drug-target interaction prediction: a game-changing approach
FragDPI, a novel drug-protein interaction prediction method, outperforms baselines and identifies specific interaction parts, aiding drug discovery
Researchers induce brain activation using infrared light-controlled drugs
This cutting-edge technique activates a specific neurotransmitter receptor using mid-infrared light, which can penetrate deep into tissue and offers unparalleled pharmacological and spatiotemporal precision in three dimensions.
ACP says ‘Enough is enough,’ vows to continue to fight for lower drug prices for patients
ACP leaders have strong words for pharmaceutical and other health care companies that are challenging the implementation of the Medicare prescription drug price negotiation program. So far, these businesses have spent approximately $400 million challenging the program in U.S. courts. ACP, along with other medical societies, is pushing back.
Opioid use disorder treatment associated with decreased risk of overdose after surgery, suggests first-of-its-kind study of over 4 million surgeries
Although people with opioid use disorder (OUD) are significantly more likely to overdose or have a complication after major surgery than those without the disorder, using medications for the treatment of OUD before surgery may eliminate that extra risk, suggests a large, first-of-its-kind study presented at the ANESTHESIOLOGY® 2023 annual meeting.
New research indicates some people may be physically unable to use police breathalysers
Some people may be physically unable to use the current evidential breath analysis machines, relied upon by police to gather proof of driving under the influence of alcohol or drugs, new research from the University of Sheffield indicates.
Investigators at Mount Sinai Find Strong Association of Kidney Injury with Dasatinib, a Commonly Used Oncological Therapeutic
Investigators at Mount Sinai Find Strong Association of Kidney Injury with Dasatinib, a Commonly Used Oncological Therapeutic Findings suggest an update may be warranted for current clinical care, screening guidelines, and FDA guidance on adverse events Principal Investigator: Evren U.…
Are antipsychotic drugs being appropriately prescribed to homebound patients with dementia?
New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer’s disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes.
Genetically engineered vesicles target cancer cells more effectively
Nanovesicles can be bioengineered to target cancer cells and deliver treatments directly, according to research at Binghamton University, State University of New York.
Digital Science boosts pharma industry support following OntoChem acquisition
Digital Science is positioning itself to play an even greater role in the pharmaceutical industry’s all-important drug discovery, by helping industry sift through a sea of information and focus on the research that matters.
Researchers track antimicrobial resistance in E. coli isolated from swine
The spread of drug-resistant microbes has become a global health concern that threatens our ability to treat infections. The widespread use of antimicrobials in livestock, such as swine farms, exacerbates this problem.
“Put profit margins aside,” says Saint Joseph’s University expert on Narcan over-the-counter approval by FDA
Narcan, a prescription nasal spray that reverses opioid overdoses, can now be sold over the counter after the FDA authorized the move on March 29. Peter A. Clark, S.J., PhD, is the director of the Institute of Bioethics and professor…
Saint Joseph’s University Expert Available to Comment on Adderall Shortage in U.S.
What: According to a recent Washington Post article, prescriptions for Adderall rose more than 30% over the past five years and accelerated during the pandemic. Now, there is a nationwide shortage of the drug. Nearly 40% of all prescriptions for stimulants, including…
Drug Linked to Lower Risk of Dementia in People with Diabetes
People with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagnosed type 2 diabetes who took the diabetes drug pioglitazone were less likely to later develop dementia than those who did not take the drug. The study is published in the February 15, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Black, Latino People with Epilepsy Less Likely to Be Prescribed Newer Drugs
Among people with epilepsy, Black, Latino and Native Hawaiian and Other Pacific Islander people are less likely to be prescribed newer drugs than white people, which can be a marker of the quality of care, according to a study published in the January 11, 2023, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology.
Calls for further research into family of antibiotics to reduce risk of serious side effects
Experts reviewing the use of a commonly prescribed family of drugs, known as fluoroquinolones, say safety warnings differ internationally
Groundbreaking research hopes to personalise treatment for cancer patients
Cancer Council SA-funded researcher Associate Professor Stephanie Reuter Lange from UniSA hopes that a simple computer program can help personalise treatment for cancer patients.
Many pain medications can be used for spine-related pain in older adults
Medications should be coupled with physical therapy, exercise programs and treatment of the underlying degenerative disease process and medical illness.
More Young People Begin Recreational Cannabis Use Illegally in States that Legalize It
Once a state legalizes recreational cannabis and increase in youth using it illegally occurs, report researchers at University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Science.
Pharmacists at Higher Risk of Suicide than General Population, Study Finds
UC San Diego study shows suicide rates were higher in pharmacists than in the general population between 2003 and 2018, with job problems being the most significant feature associated with the suicides.
Mechanisms of addiction: Psychology professor receives NIH grant for brain research
A five-year, $2.59 million grant from the National Institutes of Health will allow a psychology professor at Binghamton University, State University of New York to study the mechanisms of addiction.
$1.3 million in NIH grants to enable research into antibody-mediated drug delivery technology
Two National Institute of Health (NIH) grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences, is the Principal Investigator on both grants — $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.
Teens who use cannabis frequently more likely to have premature baby, study suggests
Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new University of Bristol-led study. The research, published in Scientific Reports, repeatedly assessed 665 participants in a general population cohort on their tobacco and cannabis use between ages 14 to 29 years, before pregnancy.
Bill Greene, PharmD, of St. Jude receives award for outstanding contributions to the pharmacy profession
William L. “Bill” Greene, PharmD, chief pharmaceutical officer, to receive the 2021 Shelby Rhinehart Public Service Lifetime Achievement Award.
Bill Greene, PharmD, of St. Jude receives lifetime achievement award
William L. “Bill” Greene, PharmD, chief pharmaceutical officer, to receive the 2021 Shelby Rhinehart Public Service Lifetime Achievement Award.
Cannabis: sexually diverse youths with depression use more
It’s no secret that studies show that sexually diverse youth – in particular, lesbian, gay and bisexual (LGB) youth – use more cannabis and experience more mental health challenges than their heterosexual peers. But what about the changes that occur…
Study shows strong association between perceived risk, availability and past-year cannabis use
Individuals who perceived cannabis as both low-risk and available were 22 times more likely to have used cannabis in the past year than those perceiving cannabis as both high-risk and unavailable
New meta-analysis finds cannabis may be linked to development of opioid use disorders
The idea that cannabis is a ‘gateway drug’ to more harmful substances such as opioids is controversial, yet has substantially impacted drug policy, education and how we conceptualize substance use. A new systematic review and meta-analysis has found that people…
ED-administered high-dose buprenorphine may enhance opioid use disorder treatment outcomes
High-dose buprenorphine therapy, provided under emergency department care, is safe and well tolerated in people with opioid use disorder experiencing opioid withdrawal symptoms, according to a study supported by the National Institutes of Health’s National Institute on Drug Abuse (NIDA)…
Study shows mental health, support, not just substance misuse key in parental neglect
Rates of clinical depression, substance use key in predicting neglectful behavior
Novel study of high-potency cannabis shows some memory effects
PULLMAN, Wash. – Even before the pandemic made Zoom ubiquitous, Washington State University researchers were using the video conferencing app to research a type of cannabis that is understudied: the kind people actually use. For the study, published in Scientific…
Study explores opioid prescribing preferences and practices among residents and faculty
CU Department of Surgery’s Victoria Huynh, MD, and Sarah Tevis, MD, are developing new protocols to improve surgical recovery
Banishing cigarettes into history’s ashcan
New grant expands Texas tobacco program, targets substance use patients in rural communities
NIH Avant Garde Award for Out-Of-Box, Innovative Concept to Cure HIV and Treat Addiction
Multi-Disciplinary Approach to Eradicate All Traces of HIV from Body, and Treat Co-existing Substance Use Disorders/Addiction
Autistic individuals more likely to use recreational drugs to self-medicate
While autistic individuals are less likely to use substances, those who do so are more likely to self-medicate for their mental health symptoms, according to new research from the University of Cambridge and published today in The Lancet Psychiatry .…
Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery
‘Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery’ gives the present status and future perspective of Polymeric nanoparticles, Liposomes, Carbon Nanotubes, Magnetic Nanoparticles, Silica Based nanomaterial, Hydrogels, Metallic Nanoparticles, Cyclodextrins, Poly (Lactide-Co-Glycolide) and its Copolymers. Improvement of a vector for…
UCI-led meta-analysis identifies hypertension medications that help ward off memory loss
Irvine, Calif., June 21, 2021 — A large-scale meta-analysis led by University of California, Irvine researchers provides the strongest evidence yet of which blood pressure medications help slow memory loss in older adults: those that can travel out of blood vessels and directly into the brain. The findings, published in the American Heart Association journal Hypertension, will be of interest to the 91 million Americans whose blood pressure is high enough to warrant medication, as well as the doctors who treat them.
Immune system dysfunction can modify the association between cannabis use and psychosis
Brazilian researchers show that a combination of inflammatory cytokines in the blood and cannabis use, daily or during adolescence, heightens the odds of developing psychiatric disorders
Association of cannabis use during adolescence with neurodevelopment
What The Study Did: Researchers examined to what extent cannabis use is associated with thickness in brain areas measured by magnetic resonance imaging in a study of adolescents. Authors: Matthew D. Albaugh, Ph.D., of the University of Vermont Larner College…
Lies to hide doping in professional sport
Göttingen University sports sociologist analyses false statements from professional cyclists
Researchers test model to predict drug overdose deaths in US
Predictive tools could help counties preemptively deliver public health resources
Are social, behavioral risk factors associated with mortality among us veterans with COVID-19?
What The Study Did: An observational study of more than 27,000 veterans who received a positive test result for COVID-19 reports that risk factors such as housing problems, financial hardship, alcohol use, tobacco use and substance use weren’t associated with…
Sleep characteristics predict cannabis use, binge drinking in teens and young adults
Circadian misalignment is a potential risk factor for substance use
People who use methamphetamine likely to report multiple chronic conditions
Medical, mental, and substance use issues all more prevalent among adults who use methamphetamine
Opioid Agonist Therapy reduces mortality risk among people with opioid dependence
A new global review has found that receiving Opioid Agonist Therapy (OAT) is associated with lower risk of multiple causes of death among people with opioid dependence. The review found that people with opioid dependence were less likely to experience…
Partners play pivotal role in pregnant women’s alcohol use and babies’ development
Rochester psychologists find successful intervention efforts need to include partners of mothers-to-be
Most buprenorphine prescriptions are written by a small number of providers
Findings have implications for increasing access to opioid abuse treatment
Emotional regulation technique may be effective in disrupting compulsive cocaine addiction
An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found. In a paper published in PNAS, the team…