U.S. Drug-related Infant Deaths More than Doubled from 2018 to 2022

Drug-involved infant deaths more than doubled (120% increase) from 2018 to 2022, with the greatest proportion of deaths in 2021 (25.8%). The most prevalent underlying causes of death included assault (homicide) by drugs, medicaments and biological substances (35.6%).

Tiny Worm Helps Uncover Long-lasting Prenatal Effects from Amphetamines

During pregnancy, the effects of therapeutical doses of amphetamine have been investigated on birth outcomes in humans. However, a thorough investigation of the mechanisms underlying the long-term effects of embryonal exposure to addictive doses of amphetamine remains largely unexplored.

Weight gain is kicked to the curb in antipsychotic drug breakthrough

World first research from the University of South Australia shows that antipsychotics can be reformulated with a strategically engineered coating that not only mitigates unwanted weight gain but also boosts serotonin levels by more than 250%.

Use of Acid Reflux Drugs Linked to Higher Risk of Migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.

ACP says ‘Enough is enough,’ vows to continue to fight for lower drug prices for patients

ACP leaders have strong words for pharmaceutical and other health care companies that are challenging the implementation of the Medicare prescription drug price negotiation program. So far, these businesses have spent approximately $400 million challenging the program in U.S. courts. ACP, along with other medical societies, is pushing back.

Opioid use disorder treatment associated with decreased risk of overdose after surgery, suggests first-of-its-kind study of over 4 million surgeries

Although people with opioid use disorder (OUD) are significantly more likely to overdose or have a complication after major surgery than those without the disorder, using medications for the treatment of OUD before surgery may eliminate that extra risk, suggests a large, first-of-its-kind study presented at the ANESTHESIOLOGY® 2023 annual meeting.

Investigators at Mount Sinai Find Strong Association of Kidney Injury with Dasatinib, a Commonly Used Oncological Therapeutic

Investigators at Mount Sinai Find Strong Association of Kidney Injury with Dasatinib, a Commonly Used Oncological Therapeutic Findings suggest an update may be warranted for current clinical care, screening guidelines, and FDA guidance on adverse events Principal Investigator: Evren U.…

Genetically engineered vesicles target cancer cells more effectively

Nanovesicles can be bioengineered to target cancer cells and deliver treatments directly, according to research at Binghamton University, State University of New York.

Digital Science boosts pharma industry support following OntoChem acquisition

Digital Science is positioning itself to play an even greater role in the pharmaceutical industry’s all-important drug discovery, by helping industry sift through a sea of information and focus on the research that matters.

Saint Joseph’s University Expert Available to Comment on Adderall Shortage in U.S.

What: According to a recent Washington Post article, prescriptions for Adderall rose more than 30% over the past five years and accelerated during the pandemic. Now, there is a nationwide shortage of the drug. Nearly 40% of all prescriptions for stimulants, including…

Drug Linked to Lower Risk of Dementia in People with Diabetes

People with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagnosed type 2 diabetes who took the diabetes drug pioglitazone were less likely to later develop dementia than those who did not take the drug. The study is published in the February 15, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Black, Latino People with Epilepsy Less Likely to Be Prescribed Newer Drugs

Among people with epilepsy, Black, Latino and Native Hawaiian and Other Pacific Islander people are less likely to be prescribed newer drugs than white people, which can be a marker of the quality of care, according to a study published in the January 11, 2023, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology.

Mechanisms of addiction: Psychology professor receives NIH grant for brain research

A five-year, $2.59 million grant from the National Institutes of Health will allow a psychology professor at Binghamton University, State University of New York to study the mechanisms of addiction.

$1.3 million in NIH grants to enable research into antibody-mediated drug delivery technology

Two National Institute of Health (NIH) grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences, is the Principal Investigator on both grants — $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.

Teens who use cannabis frequently more likely to have premature baby, study suggests

Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new University of Bristol-led study. The research, published in Scientific Reports, repeatedly assessed 665 participants in a general population cohort on their tobacco and cannabis use between ages 14 to 29 years, before pregnancy.

Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery

‘Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery’ gives the present status and future perspective of Polymeric nanoparticles, Liposomes, Carbon Nanotubes, Magnetic Nanoparticles, Silica Based nanomaterial, Hydrogels, Metallic Nanoparticles, Cyclodextrins, Poly (Lactide-Co-Glycolide) and its Copolymers. Improvement of a vector for…

UCI-led meta-analysis identifies hypertension medications that help ward off memory loss

Irvine, Calif., June  21, 2021 — A large-scale meta-analysis led by University of California, Irvine researchers provides the strongest evidence yet of which blood pressure medications help slow memory loss in older adults: those that can travel out of blood vessels and directly into the brain. The findings, published in the American Heart Association journal Hypertension, will be of interest to the 91 million Americans whose blood pressure is high enough to warrant medication, as well as the doctors who treat them.