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UrduIeDEA program analyzes health data from over 2 million people to advance HIV care
Tag: AIDS/HIV
Advancing the long-term well-being of people living with HIV
Since antiretroviral therapy (ART) for HIV was introduced in 1996, AIDS-related morbidity and mortality has declined significantly. People living with HIV are now expected to live nearly as long as people without HIV. Despite these advances, those living with HIV…
CEPI and IVI collaborate on clinical research to expand access to COVID-19 vaccines in Africa
July 20, 2021; Oslo, Norway and Seoul, Republic of Korea: The Coalition for Epidemic Preparedness Innovations (CEPI) and the International Vaccine Institute (IVI) today announced a new programme of clinical research which aims to expand access to COVID-19 vaccines in…
Study finds adolescent girls and young women in Africa will use HIV prevention products
Interim results of the REACH study of daily oral PrEP and monthly dapivirine vaginal ring presented at IAS 2021 – the 11th IAS Conference on HIV Science
Nursing organizations state their positions on systemic racism: JANAC authors analyze themes
July 7, 2021 – The murders of George Floyd and other Black Americans have prompted a national outcry against structural racism and police brutality . How are leading nursing organizations and schools of nursing defining their positions on racism? That’s…
NIH Avant Garde Award for Out-Of-Box, Innovative Concept to Cure HIV and Treat Addiction
Multi-Disciplinary Approach to Eradicate All Traces of HIV from Body, and Treat Co-existing Substance Use Disorders/Addiction
About half of people living with HIV have coronary artery plaque despite low cardiac risk
Researchers led by Massachusetts General Hospital have identified a condition with potential cardiovascular disease implications for the many people with HIV not identified by traditional risk markers.
Infusion centers associated with substantially better outcomes than the ER for patients with acute pain events and sickle cell disease
Embargoed news from Annals of Internal Medicine
ACTG announces publication of REPRIEVE sub-study in JAMA Network Open, providing insights into cardiovascular disease risk among people living with HIV
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced that findings from a sub-study of REPRIEVE (A5332/A5332s, an international clinical trial studying heart disease prevention in people living with HIV) have…
Researcher receives NIH director’s award to help end HIV global epidemic
June 28, 2021–BRONX, NY– International organizations and countries around the world are working to eliminate HIV/AIDS by 2030. To reach this goal, new approaches are needed–particularly among difficult-to-reach groups such as people who inject drugs (PWID), who are 30 times…
“Smart” segmented ring device delivers medications to stop HIV transmission
Researchers have designed a device that delivers two medications that help stop HIV transmission. Although condom usage is the best strategy for preventing HIV transmission, the researchers are working to design a device that can be used by sex workers…
Sudden cardiac death more likely to fell persons with HIV infection
Autopsies consistently find fibrosis in hearts of the HIV-positive
ACTG honors the 40th anniversary of HIV/AIDS, convenes virtual annual meeting
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, commemorates the 40th anniversary of the initial publication of reports of what came to be known as HIV/AIDS in CDC’s Morbidity and Mortality Weekly…
ACTG launches phase 1 combination HIV cure study
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the launch of A5386, a phase 1 HIV cure study evaluating two promising therapies. A5386 will study whether N-803 (a clinical-stage biologic…
Model shows sharp decrease in HIV incidence in England
England on track to achieve elimination of HIV transmission by 2030
ACTG announces the addition of two monoclonal antibodies to ACTIV-2 outpatient treatment study for COVID-19
Los Angeles, Calif. – The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the addition of two monoclonal antibodies, BMS-986414 and BMS-986413, to the COVID-19 outpatient treatment study, ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies…
NIH-funded study tests “one-stop” mobile clinics to deliver HIV, substance use care
NIH-funded study tests “one-stop” mobile clinics to deliver HIV, substance use care A clinical trial is underway in five U.S. cities to determine whether delivering integrated health services through mobile clinics can improve HIV and substance use outcomes among people…
Monoclonal antibody prevents HIV infection in monkeys, study finds
Leronlimab to be studied as potential HIV PrEP drug in an early human clinical trial
A novel tuberculosis regimen shortens treatment course for patients
Researchers at the Medical University of South Carolina and elsewhere find a new antibiotic regimen that shortens the treatment course for patients with tuberculosis
People who use methamphetamine likely to report multiple chronic conditions
Medical, mental, and substance use issues all more prevalent among adults who use methamphetamine
Marking the 40th anniversary of the AIDS epidemic: A paper in the New England Journal of Medicine
June 5, 2021 marks the 40th anniversary of the first report of AIDS cases and the onset of the American AIDS epidemic. In a new, thought-provoking paper in the New England Journal of Medicine , Professor Ronald Bayer and co-author…
How HIV infection shrinks the brain’s white matter
Researchers from Penn and CHOP detail the mechanism by which HIV infection blocks the maturation process of brain cells that produce myelin, a fatty substance that insulates neurons
Stem cell drugs surprise researchers: Could lead to better drugs in the future
A study conducted in mice by researchers at the University of Copenhagen details their function providing new knowledge that may improve stem cell transplantation and lead to better drug design in the future
Newly identified antibody can be targeted by HIV vaccines
The previously undescribed antibody points to new vaccine strategies for HIV, COVID
A brand new cocktail to fight HIV
Montréal, May 20, 2021–Researchers at the University of Montreal Hospital Research Centre (CRCHUM) and Yale University have succeeded in reducing the size of the HIV reservoir in humanized mice by using a “molecular can opener” and a combination of antibodies…
Molecule enlists patient’s immune system to combat HIV
Antiretroviral therapy, the common approach in the treatment of HIV, halts replication of the virus and has saved the lives of millions of people. However, for patients the drug cocktail becomes a lifetime necessity because they continue to harbor latent…
Mobile gaming app enhances HIV care
University of North Carolina at Chapel Hill and Duke University promote better health through gamification
A trait of the rare few whose bodies naturally control HIV: “trained” immune cells
Scientists at the Ragon Institute of MGH, MIT and Harvard discover that “elite controllers” have myeloid dendritic cells that display characteristics of trained innate immune cells.
Forty years of nursing science in HIV/AIDS: JANAC marks progress and challenges
May 4, 2021 – From the very beginning of the AIDS epidemic in 1981, nurses have been at the forefront of patient care, advocacy, and research. But even in the age of antiretroviral therapy and pre-exposure prophylaxis, many challenges remain…
An atlas of HIV’s favorite targets in the blood of infected individuals
Gladstone researchers have identified the blood cells most likely to be targeted by HIV during a real-life infection
People with HIV at high risk for intimate partner violence
Intimate partner violence found to be associated with riskier behaviors associated with elevated transmission of HIV, increased depression and anxiety, and poor adherence to HIV treatment, scientists report in the American Journal of Preventive Medicine
10,000-plus medical charts provides comparator for HIV prevention study in pregnant women
Records review conducted in four African countries published in PLOS ONE will help determine safety of PrEP and dapivirine ring in DELIVER; includes data seldom collected in these countries
Chronic viral infections can have lasting effects on human immunity, similar to aging
Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C
Diabetes drug may be a new weapon against HIV
Research from the UNC School of Medicine lab of Jenny Ting, Ph.D., shows that widely used drug metformin reduces metabolism of infected T cells to suppress HIV replication
HIV vaccine candidate’s mysteries unlocked 20 years later
Highly effective cytomegalovirus-based vaccine explained in new scientific studies
National research project bundles interventions to make gains in black women’s health
Twelve sites awarded millions to bundle and scale HIV interventions across the country
Researchers hunt for drugs that keep HIV latent
When the human immunodeficiency virus infects cells, it can either exploit the cells to start making more copies of itself or remain dormant–a phenomenon called latency. Keeping these reservoirs latent is a challenge. A new paper, published in the Proceedings…
HIV: An antidiabetic drug to reduce chronic inflammation
Researchers at the CRCHUM find that metformin could help people living with HIV who are being treated with antiretroviral therapy
Antibody Mediated Prevention (AMP) trials data published by the New England Journal of Medicine
Most advanced clinical trials testing broadly neutralizing antibody against HIV demonstrate efficacy against sensitive strains
Switching from TDF- to TAF-containing ART associated with the development of obesity in people living with HIV
Embargoed News from Annals of Internal Medicine
HIV research: Increased weight gain with TAF medication
In Switzerland about 17 000 people are living with an HIV infection, worldwide there are about 38 million. Today, the disease can be treated so successfully that a normal life can be ensured to a great extent. However, weight increases…
How can new technologies help reduce the harm of drug use?
Online platforms prove to be effective in helping people in Russia who use drugs
Comparative adjuvant trial evaluates Army-developed ALF in HIV vaccine regimens
The first vaccine has been administered in a comparative adjuvant trial of DNA prime/protein boost HIV vaccine regimens in Kericho, Kenya
WVCTSI highlighting HIV in rural America with virtual event
The West Virginia Clinical and Translational Science Institute (WVCTSI) will host a special virtual event titled “HIV in Rural America” on March 18. During this event, researchers, state, and national health experts will discuss research presented in The Lancet’s recent…
New report reveals how the U.S. can renew its leadership in global health R&D
Analysis from the Global Health Technologies Coalition provides blueprint for capitalizing on opportunities revealed by COVID-19 to defeat a range of health threats
Researchers boost potency of an HIV-1 antibody, tracing new pathways for vaccine development
LAWRENCE — Much like coronavirus, circulating HIV-1 viruses mutate into diverse variants that pose challenges for scientists developing vaccines to protect people from HIV/AIDS. “AIDS vaccine development has been a decades-long challenge partly because our immune systems have difficulty recognizing…
90-day dapivirine ring for women’s HIV prevention passes its first test in Phase I study
Development of a longer-acting ring builds on the monthly dapivirine ring currently under regulatory review
Greater tobacco use linked to higher levels of inflammation in HIV-positive people
UMass Amherst study points to health benefits from reducing cigarette smoking
BU researchers identify basic mechanisms that regulate HIV expression
(Boston)–Despite the positive advances that anti-human immunodeficiency virus (HIV) therapy, commonly called anti-retroviral therapy (ART) or highly active antiretroviral therapy (HAART), has had on the life expectancy of HIV-positive people, finding a cure for HIV or acquired immunodeficiency syndrome (AIDS)…
One size doesn’t fit all when it comes to products for preventing HIV from anal sex
The initial insights from the study, aptly named DESIRE (Developing and Evaluating Short-acting Innovations for Rectal Use), are being reported on March 6 in a Science Spotlight session at the virtual meeting of the Conference on Retroviruses and Opportunistic Infections…