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UrduPeople who develop severe COVID-19 have markedly blunted antiviral responses in the nasopharynx
Tag: IMMUNOLOGY/ALLERGIES/ASTHMA
New understanding of cell stability with potential to improve immune cell therapies
Findings highlight pathway to remove unstable cells
Early antiviral response in the nose may determine the course of COVID-19
Cells sampled at the time of diagnosis from patients who later developed severe COVID-19 show a muted antiviral response, study finds
Advantages of intranasal vaccination against SARS-CoV-2
Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract
AZ heroes study awarded $15M to continue, expand evaluation of COVID-19 immunity
A University of Arizona Health Sciences study of COVID-19 vaccine effectiveness and immunity among frontline workers has received a $15 million award from the U.S. Centers for Disease Control and Prevention (CDC) to continue the current research for another year…
Llama ‘nanobodies’ could hold key to preventing deadly post-transplant infection
Scientists have developed a ‘nanobody’ – a small fragment of a llama antibody – that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and…
Less-sensitive COVID-19 tests may still achieve optimal results if enough people tested
Analysis suggests same epidemiological outcomes possible with rapid-antigen versus RT-PCR tests
Study innovates in gluten-free formulations, creating more palatable and nutritious bread
Study at the Federal University of São Paulo developed a recipe combining chickpea flour and psyllium, a plant-derived soluble fiber. The product is nourishing and rated highly by consumers in qualitative surveys.
Study links vaccine immune response to age
New OHSU laboratory research highlights importance of increasing vaccination to protect older vaccinated adults
Precision treatment for severe asthma targets a specific mutation
Drug blocks a cell receptor that is mutated disproportionately in people of color
C is for Vitamin C — a key ingredient for immune cell function
Harnessing the combined power of Vitamin C and TET proteins may give scientists a leg up in treating autoimmune diseases
Mark Foundation funds Jackson Laboratory scientists to study immunotherapy side effects
The Mark Foundation for Cancer Research funds Jackson Laboratory scientists to take on immunotherapy’s greatest challenges — improving response rates and decreasing debilitating side effects
CEPI and IVI collaborate on clinical research to expand access to COVID-19 vaccines in Africa
July 20, 2021; Oslo, Norway and Seoul, Republic of Korea: The Coalition for Epidemic Preparedness Innovations (CEPI) and the International Vaccine Institute (IVI) today announced a new programme of clinical research which aims to expand access to COVID-19 vaccines in…
No IgA leads to intestinal inflammation in mice
Tokyo, Japan – While researchers have known for years that immunoglobulin A (IgA) is important for gut health, it has remained unclear exactly what role it plays in preventing infection and disease. But now, researchers from Japan have found that…
Coffee doesn’t raise your risk for heart rhythm problems
UCSF Cardiology researchers report no link between coffee consumption and arrhythmia
Children’s National Hospital and NIAID launch study on long-term impacts of COVID-19 and MIS-C
NIH-funded multi-year study will look at impacts on children’s physical health and quality of life
Survey Shows Rise in Vaccine Hesitancy in Ghana
Research led by the University of Southampton into the uptake of the COVID-19 vaccine in Ghana, West Africa has concluded that vaccine hesitancy has seen a small, but significant increase over the last three months.
COVID-19 antibodies persist at least nine months after infection
Testing of an entire Italian town shows antibody levels remain high nine months after SARS-CoV-2 infection, whether symptomatic or asymptomatic. Researchers from the University of Padua and Imperial College London tested more than 85 percent of the 3,000 residents of…
A simple compound to control complex gut microbes
Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria. Specifically, experiments showed that acetate could trigger an immune response against…
Researchers discover how cancer cells that spread to lymph nodes avoid immune destruction
Blood pressure drug losartan may help thwart this evasion tactic.
New theory suggests blood immune and clotting components could contribute to psychosis
A scientific review has found evidence that a disruption in blood clotting and the first line immune system could be contributing factors in the development of psychosis. The article, a joint collaborative effort by researchers at RCSI University of Medicine…
Common COVID-19 antibiotic no more effective than placebo
UCSF outpatient study found limited effect of azithromycin on progression of disease
New COVID-19 vaccine candidate provides effective option for low- to mid-income countries
A multidisciplinary team of researchers is the first to show combining yeast-expression technology and a novel adjuvant formulation to produce a COVID-19 vaccine candidate is effective against SARS-COV-2 and promises to be easy to produce at large scale and cost-effective, important aspects for vaccinating people worldwide, especially in low- to middle-income countries.
A rapid method to quantify antibodies against SARS-CoV-2
Scientists have developed a rapid, highly accurate test to detect antibodies against the spike protein of SARS-CoV-2 in human serum, opening a new avenue for understanding the full extent of the pandemic and evaluating the effectiveness of vaccines.
Protein-based vaccine candidate combined with potent adjuvant yields effective SARS-CoV-2 protection
A new protein-based vaccine candidate combined with a potent adjuvant provided effective protection against SARS-CoV-2 when tested in animals, suggesting that the combination could add one more promising COVID-19 vaccine to the list of candidates for human use. The protein…
COVID precautions may result in more breast cancer deaths
A new paper in the Journal of the National Cancer Institut e, published by Oxford University Press, indicates that disruptions in health care due to the COVID 19 pandemic may increase breast cancer deaths. In March 2020 public health measures…
An inclusive guide to Nano particles in medicine
A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles. The book also covers information about specific nanoparticle conjugates, in which nanoparticles…
Measures and clinical approach of COVID 19
The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information…
Prevention, detection and various approaches on coronaviruses
In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential. This book Coronavirus brings together essential data regarding prevention…
Role of subnuclear NSrp70 in immunity-studied at Gwangju Institute of Science & Technology
Scientists report that the alternative-splicing regulator NSrp70 influences immune T cell development
Short chain fatty acids: An ‘ace in the hole’ against SARS-CoV-2 infection
Scientists find that short chain fatty acids can be used to reduce susceptibility to SARS-CoV-2 infection and mortality from COVID-19
One shot of the Sputnik V vaccine triggers strong antibody responses
A single dose of the Sputnik V vaccine may elicit significant antibody responses against SARS-CoV-2, finds a study published July 13 in the journal Cell Reports Medicine.
More complex than we thought: The body’s reaction to contact allergens
Hair dye, perfume, jewellery. Beautifying to most, but for some they are equivalent to rashes, irritation and reduced quality of life. Together with hay fever and food allergies, allergic contact dermatitis due to exposure to e.g. nickel and perfume ingredients…
Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality
Study suggests spatial relationship between COVID-19 mortality and population-level health factors
First actionable clock that predicts immunological health and chronic diseases of aging
Research highlights the critical role of the immune system in the aging process
Changes in gut microbiome in longitudinal study of infants precede onset of celiac disease
Pre-clinical changes in the gut could inform treatment and prevention.
Sensing “junk” RNA after chemotherapy enhances blood regeneration
Hematopoietic stem cells take advantage of RNA from pathogenic remnants integrated in the genome to replenish the blood system
Scientists explore seamounts in Phoenix Islands Archipelago, gain insights into deep water diversity
Marine scientists aboard Schmidt Ocean Institute’s research vessel Falkor have identified likely new marine species and deep sea organisms on nine seamounts that were explored for the first time in the remote Phoenix Islands Archipelago. In a 34-day expedition that…
Sensitivity of the Delta variant to sera from convalescent and vaccinated individuals
COVID-19: analysis of the sensitivity of the Delta variant to monoclonal antibodies and sera from convalescent and vaccinated individuals
‘Tumor avatars’ predict patients’ response to immunotherapy
Powerful new model system to personalize cancer immunotherapy
Stem cells can use same method as plants and insects to protect against viruses
Researchers at the Francis Crick Institute have found a vital mechanism, previously thought to have disappeared as mammals evolved, that helps protect mammalian stem cells from RNA viruses such as SARS-CoV-2 and Zika virus. The scientists suggest this could one…
A summary of myocarditis cases following COVID-19
Myocarditis-or inflammation around the heart–has been reported in some patients with COVID-19. After searching the medical literature, researchers have now summarized the results of 41 studies describing myocarditis in 42 patients with COVID-19. The analysis, which is published in the…
New study shows mathematical models helped reduce the spread of COVID-19
Colorado researchers have published new findings in Emerging Infectious Diseases that take a first look at the use of SARS-CoV-2 mathematical modeling to inform early statewide policies enacted to reduce the spread of the Coronavirus pandemic in Colorado.
Children’s Hospital Colorado one of 7 US children’s hospitals driving asthma research
NIH awards $2.3 million to Colorado to support first long-term pediatric asthma study in emergency department patients experiencing asthma symptoms
Commensal bacteria ‘vaccine’ may safely prep immune cells for meningitis-causing cousin
Researchers have produced vaccine-like immune responses to a dangerous bacterium by colonizing 26 healthy volunteers with a related, but harmless, commensal bacterial species. The first-in-human, controlled infection study showed the strategy was safe, as no side effects were reported and…
New cancer findings can give wider access to immunotherapy
Researchers at Karolinska Institutet in Sweden publish new findings in the journal Cancer Discovery showing how pharmacological activation of the protein p53 boosts the immune response against tumours. The results can be of significance to the development of new combination…
Epsilon variant mutations contribute to COVID immune evasion
Studies reveal unprecedented mechanism behind loss of antibody neutralization against this pandemic coronavirus variant of concern
AID/APOBECs among important factors in body’s defence against SARS-CoV-2
A MedUni Vienna research team has now addressed the potential interrelations between AID/APOBECs and the SARS-CoV-2
Structures discovered in brain cancer patients can help fight tumors
Researchers at Uppsala University have discovered lymph node-like structures close to the tumour in brain cancer patients, where immune cells can be activated to attack the tumour. They also found that immunotherapy enhanced the formation of these structures in a…
Being clean and hygienic need not impair childhood immunity
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