An observational study of COVID-19 standard of care (SOC) measures found improvements in recovery and mortality over time in adults hospitalized with COVID-19 and investigated changes in SOC that may explain these improvements. The study is published in Annals of Internal Medicine.
Tag: MORTALITY/LONGEVITY
Association of wealth with longevity at midlife
What The Study Did: Researchers investigated the association between net worth at midlife and subsequent longevity in individuals as well as with siblings and twins. Authors: Eric D. Finegood, Ph.D., of Northwestern University in Evanston, Illinois, is the corresponding author.…
The Lancet: Experts call for urgent action to improve physical activity worldwide
Not enough progress has been made to address physical inactivity worldwide, with adolescents and people living with disabilities (PLWD) among the least likely populations to have the support needed to meet the World Health Organization (WHO)’s physical activity guidelines. Global…
More than 1.5M children lost a primary or secondary caregiver due to the COVID-19 pandemic
Addressing the impact of caregiver deaths critical for pediatric mental health, authors note
A breath of fresh air for emphysema research
Tokyo, Japan – Chronic obstructive pulmonary disease (COPD) causes illness and death worldwide. It is characterized by destruction of the walls of tiny air sacs in the lungs, known as emphysema, and a decline in lung function. Little has been…
Of lives and life years: 1918 influenza vs COVID-19
Next time, vaccination may be too little, too late
Exploring gap between excess mortality, COVID-19 deaths in 67 countries
What The Study Did: N ational health care systems have different capacities to correctly identify people who died of COVID-19. Researchers in this study analyzed the gap between excess mortality and COVID-19 confirmed mortality in 67 countries to determine the…
Association of remdesivir treatment with survival, length of hospital stay among US veterans hospitalized with COVID-19
What The Study Did: I n this observational study using data from the Veterans Health Administration for 2,344 U.S. veterans hospitalized with COVID-19, remdesivir treatment was associated with prolonged hospitalization but wasn’t associated with improved survival. Authors: Michael E. Ohl,…
Think about this: Keeping your brain active may delay Alzheimer’s dementia 5 years
MINNEAPOLIS – Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer’s dementia…
New spray could someday help heal damage after a heart attack
Heart attack, or myocardial infarction, is one of the leading causes of death worldwide. Although modern surgical techniques, diagnostics and medications have greatly improved early survival from these events, many patients struggle with the long-term effects of permanently damaged tissue,…
First actionable clock that predicts immunological health and chronic diseases of aging
Research highlights the critical role of the immune system in the aging process
Preferred life expectancy and its association with hypothetical adverse life scenarios
July 12, 2021– A new study sheds light on how the specter of dementia and chronic pain reduce people’s desire to live into older ages. Among Norwegians 60 years of age and older the desire to live into advanced ages…
The ethics of split liver transplantation: Analyzing case studies to make the right decision
Split liver transplantation (SLT) provides an opportunity to divide a donor liver and offer transplants to two small patients, one or both of whom could be a child. SLT, which is underused in the United States, could be used more…
Early blood-sugar levels in type 2 diabetes crucial for future prognosis
People who get type 2 diabetes need to gain control of their blood-sugar levels — fast. The years immediately after diagnosis are strikingly critical in terms of their future risk for heart attacks and death. This is shown by a…
Could a longer reproductive period put women at greater risk for Alzheimer disease?
New study suggests that a longer exposure to endogenous estrogen is associated with increased levels for Alzheimer disease biomarkers
Understanding frailty will lead to better care for older adults
Frailty is a better predictor than factors such as age when determining how older adults fare one year after receiving critical care. A team led by researchers from the University of Waterloo analyzed data from more than 24,000 community-dwelling older…
CNIO researchers help to decipher the structure of the large molecular machine that activates mTOR
“As our understanding of the mechanisms that control mTOR grows, new possibilities are opening up to interfere with these processes for therapeutic purposes,” says Óscar Llorca, co-author of the study
Young South Asian heart attack patients more likely to be obese, use tobacco
Increased heart disease prevention education and awareness needed for younger, at-risk patients
Castration delays DNA aging
New research shows that castration of male sheep delays aging of DNA compared to intact males
Dignity support at end of life
How a two-way approach can promote quality care
Interleukin-6 antagonists improve outcomes in hospitalised COVID-19 patients
Findings from a study published today [6 July] in the Journal of the American Medical Association ( JAMA ) have prompted new World Health Organization (WHO) recommendations to use interleukin-6 antagonists in patients with severe or critical COVID-19 along with…
Missing bile ducts offer clues to mechanism of liver injury
PITTSBURGH, July 6, 2021 – Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice. But despite…
New signaling pathway could shed light on damage repair during brain injury
The study has uncovered a signaling pathway that causes neural cells to enter divisions after damage
Do heart medications affect COVID-19 outcomes?
Cardiovascular drugs do not affect COVID-19 outcomes–such as disease severity, hospitalizations, or deaths–according to an analysis of all relevant studies published as of November 2020. The findings are published in the British Journal of Clinical Pharmacology . Investigators included 429…
New online calculator can help predict death and end-of-life care needs for older adults
Although most Canadians die from predictable causes and have health needs that can be met at home, only 20% of people receive a physician home visit in their last year of life. To help understand the changing care needs of…
Leaders’ pandemic policies engendered varying levels of trust
As the COVID-19 pandemic exploded across the globe in early 2020, the world’s leaders were faced with a flurry of tough moral dilemmas. Should schools and businesses shut down, and if so, for how long? Who should receive scarce resources,…
Survival among adults with early-onset colorectal cancer
What The Study Did: Survival among people with early-onset (diagnosed before age 50) colorectal cancer compared with later-onset colorectal cancer (diagnosed at ages 51 through 55) was compared using data from the National Cancer Database. Authors: Charles S. Fuchs, M.D.,…
We cannot cheat ageing and death
New study finds fresh evidence for our inevitable death
Sweeping analysis concludes there’s no cheating old age
Researchers compare pace-of-aging across 39 populations of humans and primates
Over half of cardiovascular disease deaths worldwide occur in Asia
Paper urges identifying epidemiological features of CVD in Asian countries to combat epidemic
Estimating excess mortality rates among US assisted living residents during pandemic
What The Study Did: The results suggest assisted living residents experienced increased mortality during the COVID-19 pandemic consistent with increases observed among nursing home residents. Authors: Kali S. Thomas, Ph.D., of Brown University in Providence, Rhode Island, is the corresponding…
Study reveals COVID-19 risk factors for those with IDD
Syracuse, N.Y. – A study of nearly 550 adults with intellectual and developmental disabilities receiving residential services in New York City found that age, larger residential settings, Down syndrome and chronic kidney disease were the most common risk factors for…
Anticoagulation in patients hospitalized with COVID-19
What The Study Did: This study of patients hospitalized with COVID-19 examines the association of anticoagulation treatment with mortality rates. Authors: Valerie M. Vaughn, M.D., M.Sc., of the University of Utah in Salt Lake City, is the corresponding author. To…
International medical graduate physician deaths from COVID-19 in US
What The Study Did: I nternational medical graduates often practice as physicians in locations and specialties less preferred by U.S. medical graduates. This study reports on physician mortality from COVID-19, and on the mortality of international medical graduates in particular.…
LSU Health New Orleans study reports compound blocks SARS-CoV-2 and protects lung cells
New Orleans, LA – Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that Elovanoids, bioactive chemical messengers made from omega-3 very-long-chain polyunsaturated fatty acids discovered by the Bazan lab in 2017, may block the virus that…
Hush little baby don’t say a word…
Giving a voice to child victims of family abuse and neglect
Are social, behavioral risk factors associated with mortality among us veterans with COVID-19?
What The Study Did: An observational study of more than 27,000 veterans who received a positive test result for COVID-19 reports that risk factors such as housing problems, financial hardship, alcohol use, tobacco use and substance use weren’t associated with…
Rapamycin changes the way our DNA is stored
Researchers discover an unexpected link between DNA winding and metabolism in the gut to ameliorate ageing
Have trouble sleeping? You’re at higher risk of dying, especially if you have diabetes
Those with diabetes, frequent sleep problems were 87% more likely to die in following 9 years
Preclinical study suggests new approach to reduce COVID-19 death among the elderly
MINNEAPOLIS/ST. PAUL (06/08/2021) — New research from the University of Minnesota Medical School and colleagues at the Mayo Clinic reveals a possible new approach to preventing death and severe disease in elderly people infected with SARS-CoV-2. The researchers demonstrated in…
People who have trouble sleeping are at a higher risk of dying – especially diabetics
In a paper published by the Journal of Sleep Research , researchers reveal how they examined data* from half a million middle-aged UK participants asked if they had trouble falling asleep at night or woke up in the middle of…
New heart metric may increase survival for heart-failure patients
A new physiological measurement of heart function developed at UVA Health could improve survival for people with heart failure by identifying high-risk patients who require tailored treatments, a new study suggests. The study is the first to show a survival…
Two-thirds of women don’t meet criteria to discontinue cervical cancer screening
Inadequate screening for older women may contribute to high cancer rates and mortality
Hospitalized individuals with active cancer more likely to die from COVID-19
Patients with blood cancers at greatest risk of COVID-19 death
Lung ultrasound can efficiently diagnose volume overload in hemodialysis patients
An abbreviated lung ultrasound protocol can efficiently determine presence of lung congestion in patients receiving hemodialysis and help expedite care. Pulmonary congestion owing to fluid overload is common among patients with kidney failure on hemodialysis (HD) and contributes to excess…
$3 million grant aims to prolong life for dialysis patients
Statisticians take deep dive into mortality factors
Antibiotics no help for mysterious lung-scarring disease, large trial finds
Doctors have hoped that antibiotics could benefit patients with chronic lung diseases, but a new study has found no benefit for patients with life-threatening idiopathic pulmonary fibrosis in preventing hospitalization or death. While there were no statistical benefits for patients…
Bar-Ilan University researchers increase life expectancy in mice by an average of 30%
The mechanism through which the protein SIRT6 acts as a ‘fountain of youth’ allows old mice to conduct the same level of vigorous activity as their young counterparts, without becoming frail
Healthy lifestyle linked to better cognition for oldest adults — regardless of genetic risk
New study suggests importance of maintaining healthy lifestyle even after age 80
Researchers create machine learning model to predict treatment with dialysis or death for hospitalized COVID-19 patients
Paper Title: Predictive Approaches for Acute Dialysis Requirement and Death in COVID-19 Journal: The Clinical Journal of the American Society of Nephrology (published online May 24, 2021) Authors: Girish Nadkarni, MD, Associate Professor in the Department of Medicine (Nephrology), Clinical…