A new way to control pain after knee replacement surgery

Houston Methodist researchers present clinical evidence supporting the safety and efficacy of injecting pain medication directly into the tibia during knee replacement surgery for better postoperative pain management. The study revealed patients receiving a mixture of morphine and vancomycin injected into the shin bone have less pain post-surgery than those who received the infusion without morphine during surgery.

Hackensack University Medical Center Offers Innovative Nonsurgical Treatment for Knee Pain Nerve-Freezing Approach Reduces Need for Opioids

Hackensack University Medical Center physicians are now offering ioverao, a handheld device that is applied in the doctor’s office before knee replacement surgery to relieve postoperative knee pain, as well as to reduce the chronic pain of knee osteoarthritis. This cryotherapy treatment has been shown to decrease patients’ use of opioids and restore mobility by reducing stiffness and discomfort.

Histamine-producing gut bacteria can trigger chronic abdominal pain

The McMaster-Queen’s research team pinpointed the bacterium Klebsiella aerogenes as the key histamine producer by studying germ-free mice colonized with gut microbiota from patients with IBS. They also colonized some mice with gut microbiota from healthy volunteers as a control group.

The study found that the bacterium Klebsiella aerogenes converts dietary histidine, an essential amino acid present in animal and plant protein, into histamine, a known mediator of pain.

AI Could Predict Ideal Chronic Pain Patients for Spinal Cord Stimulation

Spinal cord stimulation is a minimally invasive FDA-approved treatment to manage chronic pain such as back and neck pain. The ability to accurately predict which patients will benefit from this treatment in the long term is unclear and currently relies on the subjective experience of the implanting physician. A study is the first to use machine-learning algorithms in the neuromodulation field to predict long-term patient response to spinal cord stimulation.

Pain in the Neck? New Surgical Method Could be Game-changing

Anterior cervical discectomy and fusion is widely used to treat spinal disorders. The fusion involves placing a bone graft or “cage” and/or implants where the surgically removed damaged disc was originally located to stabilize and strengthen the area. The risk factors for cage migration are multifactorial and include patient, radiological characteristics, surgical techniques and postoperative factors. A study is the first to evaluate the effect of the range of motion, cage migration and penetration using variable angle screws and cervical spine models. The plate developed and tested by the researchers provided directional stability and excellent fusion, showing promising clinical outcomes for patients with degenerative cervical spine disease.

Weather can affect pain tolerance, reports study in PAIN®

Can the weather affect pain from conditions like arthritis or migraine? It may sound like an old superstition – but on some standard quantitative sensory tests, weather-related factors do indeed affect pain tolerance, suggests a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Older Adults Need More Than Clichés Like ‘Exercise is Good for You’ to Stay Active

More than 80 percent of adults get the recommended 150 minutes of moderate intensity or 75 minutes of vigorous-intensity physical activity per week. Moreover, 40 percent of Americans 75 and older are entirely inactive. Little is known about factors associated with increasing, sustaining, or declining physical activity levels over time. A study explored what drives older adults from diverse backgrounds to start or sustain physical activity and what stops them. The bottom line: knowledge and old clichés alone aren’t enough to keep them moving.

International team aims to make musculoskeletal health a global priority

An international research team has found that despite being the world’s leading cause of pain, disability and healthcare expenditure, the prevention and management of musculoskeletal health, including conditions such as low back pain, fractures, arthritis and osteoporosis, is globally under-prioritised…

Study is first to show that air pollutants increase risk of painful periods for women

Dysmenorrhea, that is, frequent severe and painful cramps during menstruation from abnormal contractions of the uterus, is the most common of all gynecological disorders. It affects between 16-91% of girls and women of reproductive age, of whom 2%-29% have symptoms…

Seeking a treatment for IBS pain in tarantula venom

For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic — or long-term — abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a…

Ibuprofen and other NSAIDs superior to codeine for managing outpatient postoperative pain

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen provide better pain control and have fewer adverse effects than codeine, a commonly prescribed opioid, when prescribed after outpatient surgery, according to new research published in CMAJ (Canadian Medical Association Journal) https:/ /…