Among the most difficult types of pain to alleviate is neuropathic pain, pain that is usually caused by damage to nerves in various body tissues, including skin, muscle and joints.
Tag: Neuropathic Pain
Gene Tiam1 orchestrates the development of chronic neuropathic pain
A group led by researchers at Baylor College of Medicine and University of Alabama at Birmingham took on the challenge of investigating the process that leads to neuropathy with the goal of identifying strategies to prevent or control it.
Evidence-based consensus guidelines on patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain
Spinal cord stimulation (SCS) has demonstrated effectiveness for neuropathic pain. Unfortunately, some patients report inadequate long-term pain relief. Patient selection is emphasized for this therapy; however, the prognostic capabilities and deployment strategies of existing selection techniques, including an SCS trial, have been questioned.
Ultrasound Device for Pain Gets ‘Nod’ from Shark Tank and NIH Funding
A project using focused ultrasound is one of seven selected by the NIH, which also has received successful reviews from ABC’s “Shark Tank.” Researchers are developing a handheld probe to provide a noninvasive, non-opioid-based treatment for aggravated chronic pain for use in a physician’s office or potentially even at home. The device directs low-intensity ultrasound at the dorsal root ganglia – small bundles of nerves along the spine that control pain signals reaching the spinal cord – to provide means for precise treatment of back and leg pain.
Molecular hydrogen as a new strategy for the treatment of chronic pain
In an article published in the journal Antioxidants, researchers from the Hospital de la Santa Creu i Sant Pau Research Institute (IIB Sant Pau) and the Universitat Autònoma de Barcelona demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances.
Elucidating the molecular targets of “eicosapentaenoic acid”: A natural remedy for chronic pain
Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions.
Not So Great Expectations: Pain in HIV Related to Brain’s Expectations of Relief
Neuroimaging study reveals potential brain mechanism underlying chronic neuropathic pain in individuals with HIV. Findings may guide new clinical treatments targeting patients’ expectations for pain relief.
Could a New Cell Type Discovery Lead to Better Chronic Pain Treatments?
Inflammation is a hallmark of chronic pain, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1+ macrophages are dysfunctional in an animal model of neuropathic pain.
Immersive virtual reality boosts the effectiveness of spinal cord stimulation for chronic pain
For patients receiving spinal cord stimulation (SCS) for chronic pain, integration with an immersive virtual reality (VR) system – allowing patients to see as well as feel the effects of electrical stimulation on a virtual image of their own body – can enhance the pain-relieving effectiveness of SCS, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer.