Older adults want to cut back on medication, but study shows need for caution

More than 82% of Americans age 50 to 80 take one or more kinds of prescription medication, and 80% of them say they’d be open to stopping one or more of those drugs — with major differences among people with different health conditions.

A genetic predisposition to alcohol use is not the same as a genetic destiny for alcohol misuse

There is a clear relationship between alcohol and neurodegeneration; for example, an alcohol use disorder correlates with a higher risk of Alzheimer’s disease. It is unclear, however, whether individual differences in brain structure and connectivity are risk factors for, or consequences of, alcohol use. New research exploring this relationship will be shared on Wednesday, 26 June 2024 at the 47th annual scientific meeting of the Research Society on Alcohol (RSA) in Minneapolis, Minnesota.

Data analysis of electronic medical records can predict adverse outcomes and suggest medications

Electronic medical records (EMRs) are digital versions of the paper charts typically found in clinician offices, clinics, and hospitals and are mostly used by healthcare providers for diagnosis and treatment. New research has leveraged EMR data analysis to predict the risk of developing adverse outcomes in the near future based on an individual’s medical history, and also pinpoint which medications may have beneficial effects.

U.S. Drug-related Infant Deaths More than Doubled from 2018 to 2022

Drug-involved infant deaths more than doubled (120% increase) from 2018 to 2022, with the greatest proportion of deaths in 2021 (25.8%). The most prevalent underlying causes of death included assault (homicide) by drugs, medicaments and biological substances (35.6%).

Patients Diagnosed With New-Onset, Persistent AFib Are More Likely to Have These Risk Factors

Patients who present with persistent atrial fibrillation at diagnosis are more likely to have certain risk factors as compared with patients with occasional atrial fibrillation (AFib). The findings, led by investigators in the Smidt Heart Institute at Cedars-Sinai, published in Circulation: Arrhythmia and Electrophysiology.

Residents of Rural ‘Glades’ Take a ‘Leap of Faith’ to Combat Dementia

Compared to urban dwellers, racially/ethnically diverse older adults face up to an 80 percent greater risk of cognitive impairment in older age, and 2.5 times potentially preventable Alzheimer’s-related (ADRD) hospitalizations.

Researchers uncover how a genetic mutation can cause individuals with normal cholesterol levels to develop coronary artery disease at a young age

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s – with normal cholesterol levels and no other risk factors — to develop coronary artery disease has been identified, according to researchers with UTHealth Houston.

Concurrent use of alcohol and cannabis leads to higher levels of drinking in the longer term

Co-existing use of alcohol and cannabis can lead to negative outcomes such as the development of a substance-use disorder, poor academic and occupational performance, and psychiatric disorders when compared to use of either drug alone. New research that examines simultaneous alcohol/cannabis use has found higher levels of drinking after 18 months. These results and others will be shared at the 46th annual scientific meeting of the Research Society on Alcohol (RSA) in Bellevue, Washington.

UCSF Internal Medicine Specialist to be Celebrated for Diabetes Epidemiology Research

Alka M. Kanaya, MD, UC San Francisco primary care physician and researcher, is being recognized with the 2023 Kelly West Award for Outstanding Achievement in Epidemiology from the American Diabetes Association (ADA). The award recognizes significant contributions to the field of diabetes epidemiology.

Expert available to comment on youth carrying guns and its implications for school safety

Dr. Hasan Buker recently published an article, co-authored with two students, titled “Carrying a handgun in public vs. taking a handgun to school among youth: an exploration of the predicting power of risk factors related to delinquency, aggression, and victimization.”  Dr. Buker, and his co-authors examined data collected from 5,648 high school…

Study Finds Disparate Gender Differences in Victims of Child Sex Trafficking

Youth involved in sex trafficking have extensive victimization experiences during childhood, and these experiences vary by gender. In the nationally representative study, 75 percent were males and 25 percent were females. Almost two-thirds of the girls were molested as a child, half were raped, and three-fourths were emotionally abused as a child, compared to 36 percent of males who were molested, 31 percent who were raped, and 37 percent who were emotionally abused. Eighty percent of females reported three or more victimization types compared to males (49 percent), and 31 percent of females experienced all five types of prior victimization compared to 11 percent of males.

Remote blood pressure management program enhanced care during pandemic

New research has found that a remote hypertension program, operated by Mass General Brigham since 2019, successfully supported patients through the pandemic in achieving their blood pressure goals, with patients who enrolled during the pandemic reaching and maintaining their goal blood pressures an average of two months earlier than in the pre-pandemic period.

Study associates long COVID with physical inactivity

The link between symptoms of COVID-19 and physical inactivity is increasingly evident. An article recently published in the journal Scientific Reports by researchers at the University of São Paulo (USP) in Brazil describes a study in which COVID-19 survivors with at least one persistent symptom of the disease were 57% more likely to be sedentary, and the presence of five or more post-acute sequelae of infection by SARS-CoV-2 increased the odds of physical inactivity by 138%.

Hair straightening chemicals associated with higher uterine cancer risk

Women who used chemical hair straightening products were at higher risk for uterine cancer compared to women who did not report using these products, according to a new study from the National Institutes of Health. The researchers found no associations with uterine cancer for other hair products that the women reported using, including hair dyes, bleach, highlights, or perms.

Nationally representative study shows disparities persist in lipid control

Physician-scientists assessed whether lipid concentrations and rates of lipid control changed among U.S. adults from 2007 to 2018. The researchers observed that while mean cholesterol concentrations improved among U.S. adults overall during this time period, there were concerning variations in these trends by race and ethnicity.

CHOP-led Study Finds Daycare Linked to Increased Complications in Preterm Children with Chronic Lung Disease

Attending daycare in the first three years of life is linked with an increase in lung complications in children who were born prematurely and diagnosed with a form of chronic lung disease, according to new research led by Children’s Hospital of Philadelphia (CHOP).

Black Patients Found Six Times More Likely to Have Advanced Vision Loss After Glaucoma Diagnosis Than White Patients

Black patients have a dramatically higher risk of advanced vision loss after a new diagnosis of primary open angle glaucoma (POAG) when compared to white patients, according to a new study from New York Eye and Ear Infirmary of Mount Sinai (NYEE).

Forever Chemicals Linked to Hypertension in Middle-Aged Women

Middle-aged women with higher blood concentrations of common synthetic chemicals called per- and polyfluoroalkyl substances (PFAS), also called “forever chemicals” and found in water, soil, air and food, were at greater risk of developing high blood pressure, compared to their peers who had lower levels of these substances, according to new research published today in Hypertension, an American Heart Association journal.

Risk Factors for Dementia May Vary with Age

Which vascular risk factors are associated with the risk of developing dementia may vary with age. A new study shows that among people around age 55, the risk of developing dementia over the next 10 years was increased in those with diabetes and high blood pressure. For people around 65 years old, the risk was higher in those with heart disease, and for those in their 70s, diabetes and stroke. For 80-year-olds, the risk of developing dementia was increased in those with diabetes and a history of stroke, while taking blood pressure medications decreased the risk. The study is published in the May 18, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Sleep Disruption Predicts Drinking and Cannabis use in Young People, with Middle and High School Students Potentially Most Vulnerable

A five-year study has highlighted the importance of healthy sleep patterns in relation to future binge-drinking and cannabis use in adolescence and young adulthood, as reported in Alcoholism: Clinical and Experimental Research. The work builds on growing evidence that sleep characteristics are predictive of future substance use and related problems in young people, and could inform strategies for substance use prevention and intervention. Most previous studies assessed only a small range of sleep characteristics, and had limited follow-up. In the new analysis, researchers used six annual assessments from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study to examine whether multiple sleep characteristics in any year predict alcohol and cannabis use the following year. Data from over eight hundred NCANDA study participants, aged 12 to 21 at baseline, were included.