Viruses found hiding in lungs’ immune cells long after initial illness

A study by researchers at WashU Medicine shows that respiratory viruses can hide out in immune cells in the lungs long after the initial symptoms of an infection have resolved, creating a persistently inflammatory environment that promotes the development of chronic lung diseases such as asthma.

CHOP-led Study Finds Daycare Linked to Increased Complications in Preterm Children with Chronic Lung Disease

Attending daycare in the first three years of life is linked with an increase in lung complications in children who were born prematurely and diagnosed with a form of chronic lung disease, according to new research led by Children’s Hospital of Philadelphia (CHOP).

Dr. Laurie Eldredge Receives ATS Research Program/American Lung Association Partner Grant

The ATS Research Program and the American Lung Association have awarded Laurie Eldredge, MD, PhD, of the University of Washington/Seattle Children’s Hospital a $100,000 Partner Grant. The ATS Research Program Partner Grants provide crucial support to talented investigators from around the world, launching careers dedicated to scientific discovery and better patient care.

Immune cell implicated in development of lung disease following viral infection

Scientists at Washington University School of Medicine in St. Louis have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection. The evidence suggests that activation of this immune cell serves as an early switch that, when activated, drives progressive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).

New strategy blocks chronic lung disease in mice

A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.

NIH study shows hyaluronan is effective in treating chronic lung disease

NIH researchers and their collaborators found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of COPD. Hyaluronan is a sugar secreted by living tissue that acts as a scaffold for cells. Utilized as a treatment, hyaluronan decreased the number of days in the hospital.