Can the Gut Cope with Night Exercise?

Gut issues are common with endurance exercise, ranging from mild discomfort to severe debilitating symptoms warranting reduced exercise workload or even cessation from activity. Considering the recent exponential growth of nighttime endurance and ultra-endurance events, athletes anecdotally report having more…

IL-28 Cytokine’s Epithelial Barrier Regulation May Lead to Targeted Treatment for Crohn’s Disease

Article title: Interleukin-28A induces epithelial barrier dysfunction in [Crohn’s disease] patient-derived intestinal organoids Authors: Pan Xu, Heike Becker, Montserrat Elizalde, Marieke Pierik, Ad A.M. Masclee, Daisy M.A.E. Jonkers From the authors: “These results identified IL-28A as a novel regulator of…

New strategy blocks chronic lung disease in mice

A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.