Mount Sinai Study Identifies Genetic Link Between Inflammatory Bowel Disease and Parkinson’s Disease

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson’s disease (PD). Published in Genome Medicine on May 13, their study highlights the potential for joint therapeutic strategies to target these two challenging disorders.

Mount Sinai Scientists Discover the Cellular Functions of a Family of Proteins Integral to Inflammatory Diseases

In a scientific breakthrough, Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

Genetics, Sex and Smoking Linked to More Health Issues for IBD Patients

Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.

Cedars-Sinai July Research Highlights

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.

Belly Fat Hinders Digestive Disease Medications

The mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at Cedars-Sinai found that inflammatory bowel disease (IBD) patients with higher levels of intra-abdominal visceral adipose tissue– a distinctive type of fat inside the abdomen −had lower rates of remission when treated with certain anti-inflammatory medications.

Digestive Disease Week 2023: Cedars-Sinai Experts Share Latest Research, Care Innovations

Digestive Disease Week (DDW) is the largest international gathering of physicians, researchers, and academics in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery. DDW2023 will take place May 6-9 in Chicago and showcase 3,100 abstracts and hundreds of lectures on the latest advances in GI research, clinical practice and technology.

The use of artificial sweeteners have been investigated for their potential negative consequences in a number of chronic conditions.

Dr. Abigail Basson, PhD, RD, LD, is a registered dietitian and NIH-funded Instructor in the Department of Nutrition with a secondary appointment with the Division of Gastroenterology, School of Medicine at Case Western Reserve University. Abigail’s research goal is to…

Improving Disease Monitoring for Hispanic Children With IBD

Study aims to adjust the Pediatric Ulcerative Colitis Activity Index to better reflect disease activity in Hispanic children. New research at Children’s Hospital Los Angeles is aiming to improve the accuracy of the Pediatric Ulcerative Colitis Activity Index (PUCAI) for Hispanic children. A simple questionnaire that’s widely used to monitor disease activity, the PUCAI tool has been well-studied and validated—but mainly in white populations.

Tipsheet: Cedars-Sinai Digestive Disease Experts Share Latest Research and Honors at the ACG 2022 Scientific Meeting

Cedars-Sinai physicians and scientists will share the results of new research aimed at improving the treatment of digestive diseases during the international meeting of the American College of Gastroenterology (ACG). The clinical conference will take place Oct. 21-26 in Charlotte, North Carolina, and is available for virtual and in-person attendance.

April Research Highlights

This tipsheet highlights the latest medical discoveries and faculty news at Cedars-Sinai. Links to full news releases are included with each item.

IL-28 Cytokine’s Epithelial Barrier Regulation May Lead to Targeted Treatment for Crohn’s Disease

Article title: Interleukin-28A induces epithelial barrier dysfunction in [Crohn’s disease] patient-derived intestinal organoids Authors: Pan Xu, Heike Becker, Montserrat Elizalde, Marieke Pierik, Ad A.M. Masclee, Daisy M.A.E. Jonkers From the authors: “These results identified IL-28A as a novel regulator of…