Improving Disease Monitoring for Hispanic Children With IBD

Study aims to adjust the Pediatric Ulcerative Colitis Activity Index to better reflect disease activity in Hispanic children. New research at Children’s Hospital Los Angeles is aiming to improve the accuracy of the Pediatric Ulcerative Colitis Activity Index (PUCAI) for Hispanic children. A simple questionnaire that’s widely used to monitor disease activity, the PUCAI tool has been well-studied and validated—but mainly in white populations.

Tipsheet: Cedars-Sinai Digestive Disease Experts Share Latest Research and Honors at the ACG 2022 Scientific Meeting

Cedars-Sinai physicians and scientists will share the results of new research aimed at improving the treatment of digestive diseases during the international meeting of the American College of Gastroenterology (ACG). The clinical conference will take place Oct. 21-26 in Charlotte, North Carolina, and is available for virtual and in-person attendance.

April Research Highlights

This tipsheet highlights the latest medical discoveries and faculty news at Cedars-Sinai. Links to full news releases are included with each item.

IL-28 Cytokine’s Epithelial Barrier Regulation May Lead to Targeted Treatment for Crohn’s Disease

Article title: Interleukin-28A induces epithelial barrier dysfunction in [Crohn’s disease] patient-derived intestinal organoids Authors: Pan Xu, Heike Becker, Montserrat Elizalde, Marieke Pierik, Ad A.M. Masclee, Daisy M.A.E. Jonkers From the authors: “These results identified IL-28A as a novel regulator of…