David Winter, MD, at Baylor Scott & White Health, discusses why cancer is impacting more young people. What You Need to Know: People aged 50 and older are living longer because of better cancer detection and treatments. Cancer diagnosis in…
Tag: Colon Cancer
Transcription Factor Plays Pivotal Role in Right-Sided Colon Cancers
The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers. New research in mice from investigators at the Johns Hopkins Kimmel Cancer Center demonstrates that these regions also have distinct transcriptional programs, or cellular processes, that regulate the development of normal and cancerous cells.
Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer
New research from the University of Ottawa proposes using vanoxerine as a safe method for potentially eliminating cancer stem cells in colorectal tumors.
Colorectal Cancer Patients in Sub-Saharan Africa Receiving Inadequate Care; Survival After Diagnosis Poor, New Study Shows
In new findings led by researchers at the American Cancer Society, Martin-Luther University in Germany, and many other institutes worldwide, fewer than one in 20 patients diagnosed with potentially curable colorectal cancer received standard of care in Sub-Saharan Africa.
Mayo Clinic researchers publish key findings about cell proteins to determine effectiveness of immunotherapy for colon cancer
Mayo Clinic Comprehensive Cancer Center researchers have identified key findings that can assist clinicians in predicting whether a patient with advanced colorectal cancer will benefit from immunotherapy.
Mutations in blood stem cells can exacerbate colon cancer
Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster.
GI symptoms persist in older female colorectal cancer survivors
More than 4 out of 5 older women survivors of colorectal cancer may be experiencing a range of gastrointestinal symptoms many years after being diagnosed and treated, a new study suggests.
Baylor Scott & White Health Again the Most-Awarded Health System in Texas for Clinical Care and Patient Experience
Baylor Scott & White Health once again leads the state of Texas in the number of accolades earned in U.S. News & World Report’s 2023-24 Best Hospitals, released today. A total of 26 Baylor Scott & White hospitals were recognized, including four facilities with a nationally ranked specialty – more than any other health system in Texas.
Baylor Scott & White Health Again the Most-Awarded Not-for-Profit Health System in Texas for Clinical Care and Patient Experience
Baylor Scott & White Health once again leads the state of Texas in the number of accolades earned in U.S. News & World Report’s 2023-24 Best Hospitals, released today. A total of 26 Baylor Scott & White hospitals were recognized, including four facilities with a nationally ranked specialty – more than any other health system in Texas.
AI Tool Predicts Colon Cancer Survival, Treatment Response
New AI tool accurately predicts both overall survival and disease-free survival after colorectal cancer diagnosis.
The model uses visual markers on pathology images to glean insights into a tumor’s genomic profile and predicts tumor behavior, disease progression, treatment response.
The new model could help augment clinical decision-making.
Because the AI tool relies on images alone, it could be particularly valuable for hospitals lacking the technology or expertise to perform sophisticated genomic profiling of tumor tissues.
New method of clustering colorectal cancer patients using DPE sequencing
A new editorial paper was published in Oncoscience (Volume 10) on March 23, 2023, entitled, “New method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing.”
Researchers Use Colon Organoids to Explore Why Aspirin Protects against Cancer
Article title: Genomic and epigenomic responses to aspirin in human colonic organoids Authors: David Witonsky, Margaret C. Bielski, Jinchao Li, Kristi M. Lawrence, Ishmael N. Mendoza, Hina Usman, Sonia S. Kupfer From the authors: “This is the first study to…
Could Altering the Gut Microbiome be a Potential New Treatment Option for Patients With Colorectal Cancer?
Studies show that certain bacteria may contribute to the development of colorectal cancer by producing toxins that may damage colon cells or cause an accumulation of DNA mutations and/or intestinal inflammation. Now, researchers are looking at the possibility that certain…
Salmonella exposure a risk for colon cancer
Researchers studied human colon cancer tissue samples and animal models and found that exposure to salmonella was linked with colon cancers that developed earlier and grew larger.
Surgery First for Colon Cancer? Not So Fast, According to New Study in JNCCN
New research in JNCCN finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).
Study Identifies New Gene That Drives Colon Cancer
Researchers have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells.
Rutgers Colonoscopy Expert Available to Discuss New Efficacy Study
Nikolaos T. Pyrsopoulos, chief of the division of gastroenterology and hepatology at Rutgers New Jersey Medical School, is available to discuss the NEJM study on the efficacy of colonoscopy in detecting colon cancers and extending life. If you do not…
Pairing imaging, AI may improve colon cancer screening, diagnosis
A research team from the lab of Quing Zhu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering at the McKelvey School of Engineering at Washington University in St. Louis, has combined optical coherence tomography (OCT) and machine learning to develop a colorectal cancer imaging tool that may one day improve the traditional endoscopy currently used by doctors.
Eligible younger U.S. adults less likely to meet recommended colorectal cancer screening guidelines and face greater disparities
Younger adults living in the U.S. are less likely to be screened for colorectal cancer than older U.S. adults, despite now being eligible under new screening guidelines, and face greater disparities than older U.S. adults who are eligible for screening, according to research from UTHealth Houston.
Plant virus plus immune cell-activating antibody clear colon cancer in mice, prevent recurrence
A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system’s “natural killer” cells, shows a study by researchers at the University of California San Diego. In mouse models of colon cancer, the combination therapy eliminated all tumors and prevented their recurrence, which in turn resulted in 100% survival. The therapy also increased survival in mouse models of melanoma.
Scientists Create Nanoparticle That Helps Fight Solid Tumors
Researchers from Wake Forest University School of Medicine have discovered a possible new approach in treating solid tumors through the creation of a novel nanoparticle.
DNA Shed From Colon Cancers Into Bloodstream Successfully Guides Chemotherapy After Surgery
A multi-institutional, international study, led by researchers at the Johns Hopkins Kimmel Cancer Center and WEHI in Melbourne, Australia, found that testing for ctDNA after surgery and directing chemotherapy to ctDNA-positive patients reduced the use of chemotherapy overall without compromising recurrence-free survival.
Zulu Social Aid and Pleasure Club Presents Men’s Health Fair, Sponsored by Ochsner Xavier Institute of Health Equity and Research
Zulu Social Aid and Pleasure Club Presents Men’s Health Fair, Sponsored by Ochsner Xavier Institute of Health Equity and Research.
DeepGI AI – A Thai Innovation for the Precision in Colorectal Polyp Detection
Chula Engineering and Chula Medicine co-invent an innovative device for a rapid gastrointestinal cancer detection that yields accurate results hoping to foster preventive medicine in gastrointestinal malignancy and reduce the number of cancer patients.
New Research Finds Computer Assisted Colonoscopy Identify More Precancerous Polyps Compared to Traditional Colonoscopy
Colonoscopies performed with artificial intelligence saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, according to new data presented at the 2022 Digestive Disease Week Annual Meeting.
Colon Microbes Provide Clues to Favorable Treatment Options in a Subset of Colon Cancer Patients
Investigators from Rutgers Cancer Institute of New Jersey, New Jersey’s only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.
Curcumin formulation to reduce colon inflammation
A safe, localized treatment for chronic inflammation in the intestinal tract will move one step closer to helping patients reduce their risk of developing colon cancer.
Best-Selling Cookbook Author Sarah Copeland Hosts Cooking Demonstration for the Colorectal Cancer Community
Fight Colorectal Cancer Hosts Gut-Friendly Cooking Event Alongside Best-Selling Cookbook Author and Former Food Director at Real Simple.
New Noninvasive Tests for Colon and Prostate Cancer Presented at the 2021 AACC Annual Scientific Meeting
Two research teams have developed new noninvasive tests that use either blood or saliva samples to diagnose cases of colorectal cancer or prostate cancer, respectively. Presented today at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo, these tests could facilitate screening efforts for colorectal cancer and allow clinicians to better distinguish early-stage prostate cancer from more benign prostate conditions.
Gut bacteria might be an indicator of colon cancer risk
Researchers are finding a link between the increased presence of certain bacteria in a gut biome and colon cancer.
Maternal obesity during pregnancy linked to higher risk of colorectal cancer in adult offspring
Infants whose mothers were obese during pregnancy may have a heightened risk of developing colorectal cancer later in life, according to new research led by public health experts at The University of Texas Health Science Center at Houston (UTHealth).
Fight Colorectal Cancer and Guardant Health Join Forces to Recognize Excellence in Overcoming Challenges to Colorectal Cancer Screening During Pandemic
Selected Recipients of the New “Back to Screening Award for Research Advocacy Excellence” will be Honored at Fight Colorectal Cancer’s “Path to a Cure” Event in December 2021.
New Patient Guide from NCCN Jumpstarts Important Conversations About Anal Cancer
New and updated patient and caregiver resources from National Comprehensive Cancer Network (NCCN) offer jargon-free, state-of-the-art information on diagnosis, treatment, and surveillance for anal, colon, and rectal cancers.
Global Event Will Advance Early Age Onset Colorectal Cancer Research
In many countries around the world, patients under age 50 are fighting, some dying, of colon and rectal cancers. Early-Age Onset Colorectal Cancer is an urgent issue in cancer research and patient care around the globe. We all want to know why this is happening, fully aware that for some, time is running out.
Colonoscopies should start at age 45, new guidelines say
Dr. Rachel Issaka, a gastroenterologist and assistant professor with UW Medicine, talks about the significance of the new recommendation and what it may mean for the Black community.
Why Is Lowering The Colorectal Cancer Screening Age to 45 A Big Deal?
Today, the United States Preventive Services Task Force (USPSTF) finalized its recommendation to adapt the colorectal cancer (CRC) screening guidelines and lower the age to begin screening to 45 instead of 50. “Shifting current age-specific screening rates to five years…
Mental Health Support: Study Reveals Huge Need Amongst Colorectal Cancer Patients
This Mental Health Awareness Month, Fight Colorectal Cancer, is urging the clinician and patient communities to take mental health seriously and connect patients with resources.
Patient reactions to colorectal cancer estimated to become the leading cause of cancer-related deaths for those 20-49 by 2030
In a recent JAMA publication, researchers predict, “For the age group 20-49, colorectal cancer was estimated to become the leading cause of cancer-related deaths by 2030.” Fight Colorectal Cancer (Fight CRC), the nation’s leading advocacy organization, is committed to amplifying…
NYU Langone Seeks to Close the Gap in Colorectal Cancer Disparities with $2.2 Million Cohen Foundation Grant
NYU Langone Health will expand colorectal cancer screenings to address disease disparities in underserved communities with a $2.2 million grant from the Steven & Alexandra Cohen Foundation.
Rock Musicians Rufus Wainwright, Lisa Loeb, Tim Reynolds and More to Perform Free Virtual Concert for Colorectal Cancer Awareness
The American College of Gastroenterology Invites All to “Tune It Up: A Concert To Raise Awareness of Colorectal Cancer” Free Webstream Event Open to All on March 31, 2021 at 8:00 pm EDT
Baby Aspirin Linked to Lower Risk of Colorectal Cancer Death
Long-term, regular use of baby aspirin—at least 15 times per month—prior to a diagnosis of colorectal cancer (CRC) may reduce the risk of death from the disease by limiting the spread of cancerous tumors pre-diagnosis, according to a study led by Cedars-Sinai Cancer researchers.
GI OnDEMAND Announces Partnership with Ambry Genetics for Genetic Testing and Counseling Services
GI OnDEMAND®, gastroenterology’s leading multidisciplinary virtual integrated care platform today announced a partnership with Ambry Genetics®, a leading clinical genetic testing company, to integrate online genetic counseling and testing services into gastroenterology practices nationwide. This partnership addresses a critical clinical need for identifying hereditary GI cancer syndromes to help guide potentially life-altering health care decisions.
GI OnDEMAND, a joint venture between the American College of Gastroenterology and Gastro Girl, Inc., will now offer the CARE (Comprehensive, Assessment, Risk, and Education) Program™ from Ambry Genetics.
American College of Gastroenterology Issues Updated Colorectal Cancer Screening Guidelines
The American College of Gastroenterology has issued updated evidence-based screening guidelines for colorectal cancer (CRC), including a new recommendation to begin CRC screening at age 45 for average risk adults. Key updates include recommendations for screening individuals with family history of CRC or polyps, guidance on the use of aspirin to reduce the risk of CRC, quality indicators for adenoma detection rate and colonoscopy withdrawal time, as well as suggestions about evidence-based interventions to boost screening rates, especially among African Americans. The authors distinguish between one-step screening tests, such as colonoscopy, and two-step screening tests that require colonoscopy, if positive, in order to complete the screening process.
The Medical Minute: Colonoscopy comes calling earlier under new screening guidelines
Evolving evidence shows screening tests should actually start at age 45 for people at average risk for colorectal cancer. Two Penn State Health doctors discuss new guidelines.
March is the Month to Get to the Bottom of Colorectal Cancer
Discussions about digestion and elimination can be embarrassing, so many people, young and old, tend to avoid them. But ignoring the topic and skipping colorectal cancer screening can lead to deadly results, experts say.
Colonoscopy: Yes, This is a Test
Colorectal cancer is the second leading cause of cancer death for both men and women, according to the Centers for Disease Control and Prevention (CDC), even though 90 percent of people who are diagnosed through early testing can be cured.
Putting the Spotlight on Colorectal Cancer Risk and Prevention during Colorectal Cancer Awareness Month
Colorectal Cancer Screening Saves Lives Colorectal cancer is the third most common cause of cancer related death for both men and women. However, if it is caught early, colorectal cancer has a 90% survival rate. This is why screening is…
UCLA expert available to discuss colorectal cancer screening prevention, more during Colorectal Cancer Awareness Month
Folasade May, MD, PhD, UCLA Health colon cancer prevention researcher and gastroenterologist, is available for interview on a variety of topics during colorectal cancer awareness month, including: Why it’s so important to not skip colorectal cancer screenings — even though…
Year or More Delay Between Abnormal, At-Home Screening and Colonoscopy Increases Cancer Risk
A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer.
Strange colon discovery explains racial disparities in colorectal cancer
The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer – the cancer that killed beloved “Black Panther” star Chadwick Boseman.