Metastasis | sciencenewsnet.in

Predicting Cancer Behavior Requires Better Understanding of Tumor Cells

June 9, 2020 sarah Jonas Biomicrofluidics, Cancer, Cellular Biology, Diagnostic, Metastasis, Tumor cell, University of California, Berkeley

Our ability to predict who will get cancer, how patients will respond to treatment, or if patients will relapse is still quite limited, despite advances in the detection of genetic mutations and the establishment of risk factors; recently researchers were inspired to find new ways of looking at the problem. In Biomicrofluidics, they report that using cellular mechanophenotyping, along with traditional methods such as immunostaining and genetic analysis, may provide a more comprehensive view of a tumor.

Research Results

Continued nicotine use promotes brain tumors in lung cancer patients, Wake Forest study suggests

June 4, 2020 sarah Jonas Brain Metastasis, Lung Cancer, Metastasis, Nicotine, Smoking, Smoking Cessation

Researchers at Wake Forest School of Medicine have discovered that nicotine promotes the spread of lung cancer cells into the brain, where they can form deadly metastatic tumors. The study, which will be published June 4 in the Journal of Experimental Medicine (JEM), suggests that nicotine replacement therapies may not be suitable strategies for lung cancer patients attempting to quit smoking. In addition, the researchers show that the naturally occurring drug parthenolide blocks nicotine-induced brain metastasis in mice, suggesting a potential therapeutic option in humans.

Research Results

Using new genomic technology, UCI researchers discover breast cancer cells shift their metabolic strategy in order to metastasize

March 6, 2020 sarah Jonas Breast Cancer, Metabolism, Metastasis, single cell, TNBC, UCI School of Medicine

New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality in breast cancer patients.
According to a study, published today in Nature Cell Biology, breast cancer cells shift their metabolic strategy in order to metastasize. Instead of cycling sugar (glucose) for energy, they preferentially use mitochondrial metabolism.

Research Results

NUS researchers discover breakthrough in cancer diagnosis using big data analytics

January 14, 2020 sarah Jonas 0 Comments Big Data, Cancer, Cancer Treatments, Immunotherapy, liquid biopsy, Metastasis

A team of researchers from the National University of Singapore has developed a personalised assessment tool which can detect the incidence of cancer, predict patient survivability and determine patient suitability for immunotherapy cancer treatment.

Research Results

Scientists identify protein associated with ovarian cancer that exacerbates neurodegeneration in Alzheimer’s

January 13, 2020 sarah Jonas 0 Comments Alzheimber's Disease, Amyloid Beta, Metastasis, Neurodegeneration, Ovarian Cancer

Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer’s disease, by combining computational methods and lab research.