Low dose colchicine associated with lower incidence of total knee and hip replacements

An exploratory analysis of the LoDoCo2 (Low-Dose Colchicine 2) randomized, controlled, double-blind trial found that daily therapy with a low dose of colchicine was associated with lower incidences of both total knee replacement and total hip replacement surgeries. The analysis is published in Annals of Internal Medicine.

Chula Medicine Determines “Cytokines” as Indicator of “Degenerative Joints” Giving Hopes for Better Disease Mitigation

Chula Medicine announced the discovery of “cytokines” in the body’s immune system that can determine the severity of osteoarthritis in elderly adults, hoping to facilitate the planning of follow-up and treatment of the disease, and reduction of its severity, while also recommending vitamin D and vitamin E supplements, body weight control, and proper exercise.

Considering More Than One Joint Replacement to Relieve Arthritis Pain?

When Lorry Graham needed multiple joint replacement surgeries for severe arthritis pain, she turned to Dr. Geoffrey Westrich at Hospital for Special Surgery. Mrs. Graham, who jokingly refers to herself as a “bionic woman,” and Dr. Westrich explain what to expect and give advice for the best outcome.

Oral Methotrexate Significantly Improves Function in People with Primary Knee OA with Inflammation After Only Three Months

A new study presented at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

Total Joint Replacement and the Impact on Future Falls in Osteoarthritis Patients

Patients who have had a total joint arthroplasty (TJA) demonstrate excellent long-term outcomes with increased mobility and improved ability to complete their activities of daily living. However, there is still an ongoing debate whether patients who have undergone TJA are at an increased risk of falls and fragility fractures. According to a new research article published in the Journal of the American Academy of Orthopaedic Surgeons®, authors compared the fall rates of nearly 500,000 cases of osteoarthritic patients and found those who underwent TJA experienced a significantly lower number of falls post-op than those who did not have the surgery.

Orthopaedic Surgeons Available to Comment on Musculoskeletal Healthcare News and Trends, Treatment Options, Fall Prevention and More

Secretary Clinton’s fractured elbow. Sonia Sotomayer’s broken ankle. Jane Fonda’s knee replacement. If you need an expert to discuss any of these timely topics, the American Academy of Orthopaedic Surgeons (AAOS) can provide expert sources to comment on musculoskeletal injury prevention, diagnosis and treatment.

Advanced Hip and Knee Replacement Techniques Lead to Faster Recovery at NYU Langone Hospital–Brooklyn

Joshua C. Rozell, MD, specializes in advanced hip and knee replacement techniques at NYU Langone Hospital–Brooklyn that include minimally invasive anterior approach hip replacement, computer-navigated and robotic knee replacements, and outpatient joint replacement surgery.

Methotrexate Significantly Reduces Joint Damage Progression Over Placebo in Erosive Hand OA, and May Facilitate Bone Remodeling

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems to facilitate bone remodeling in these patients