osteoarthitis

Oral Methotrexate Significantly Improves Function in People with Primary Knee OA with Inflammation After Only Three Months

A new study presented at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

Total Joint Replacement and the Impact on Future Falls in Osteoarthritis Patients

Patients who have had a total joint arthroplasty (TJA) demonstrate excellent long-term outcomes with increased mobility and improved ability to complete their activities of daily living. However, there is still an ongoing debate whether patients who have undergone TJA are at an increased risk of falls and fragility fractures. According to a new research article published in the Journal of the American Academy of Orthopaedic Surgeons®, authors compared the fall rates of nearly 500,000 cases of osteoarthritic patients and found those who underwent TJA experienced a significantly lower number of falls post-op than those who did not have the surgery.

Methotrexate Significantly Reduces Joint Damage Progression Over Placebo in Erosive Hand OA, and May Facilitate Bone Remodeling

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems to facilitate bone remodeling in these patients