Article title: Physiological predictors of morbidity and mortality in COPD: the relative importance of reduced inspiratory capacity and inspiratory muscle strength Authors: Devin B. Phillips, Matthew D. James, Conor D. O’Donnell, Sandra G. Vincent, Katherine A. Webb, Juan P. de-Torres,…
Article title: Recombinant human β-defensin 2 delivery improves smoking-associated lung neutrophilia and bacterial exacerbation Authors: Nadia Milad, Marie Pineault, Gabrielle Bouffard, Michaël Maranda-Robitaille, Ariane Lechasseur, Marie-Josée Beaulieu, Sophie Aubin, Benjamin A. H. Jensen, Mathieu C. Morissette From the authors: This…
The American Thoracic Society Research Program today announced the six recipients of the Non-Profit Partner Grants for the 2021-2022 grant cycle. These grants are awarded through partnerships with the American Lung Association, CHEST Foundation, COPD Foundation, and the Foundation for Sarcoidosis Research.
Prescott Woodruff, MD, MPH, a renowned leader in the pathogenesis and treatment of airway disease, has been appointed chief of UC San Francisco’s Division of Pulmonary, Critical Care, Allergy and Sleep Medicine. Prescott will assume the role of chief on July 1.
Researchers from the Centenary Institute and the University of Technology Sydney have published the first study showing why people with chronic obstructive pulmonary disease (COPD) are at higher risk of developing severe COVID-19.
Patients with chronic obstructive pulmonary disease (COPD) often have other comorbid disorders, a new study from Norway shows.
The Challenge seeks to reduce 30-day readmissions for: acute myocardial infarction (AMI); chronic obstructive pulmonary disease (COPD); heart failure (HF); pneumonia; coronary artery bypass graft (CABG) surgery; and elective primary total hip arthroplasty and/or total knee arthroplasty (THA/TKA).
Due to COVID-19 and a rapidly expanding list of conditions for which lung transplantation can be lifesaving, the need for new organs is growing. However, there’s a global shortage of donated lungs, which results in numerous deaths among patients on the waitlist. To help expand the donor pool, Northwestern Medicine is now using a device from XVIVO called XPS™ which is used for ex vivo lung perfusion (EVLP) – nicknamed “lungs in a box” – to rescue potentially viable lungs and those initially deemed “unacceptable” for transplant. Out of all solid organs, lungs have the lowest utilization, with only one in five donated lungs getting transplanted.
Rockville, Md. (November 8, 2021)—The activation of muscarinic acetylcholine (M2) receptors could be one of the causes of diseases like asthma and chronic obstructive pulmonary disease (COPD), according to the findings of a new study in the journal Function. The…
This discovery, published in the Proceedings of the National Academy of Sciences (PNAS), suggest that MUC5AC could become a target of better therapeutics to untangle the super thick and sticky mucus that plays a role in health problems for millions of people suffering from pulmonary conditions.
A new study published online in the Annals of the American Thoracic Society provides the most exhaustive look to date at the risk factors, prevalence and population attributable risk (PAR) of developing chronic obstructive pulmonary disease (COPD) in U.S. Hispanics/Latinos under age 50. PAR estimates the proportion of disease attributable to exposure to disease-causing agents, such as smoking. The researchers used PAR to calculate the burden of early COPD that would be eliminated if the exposure did not take place.
Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells—the cells that line the walls of blood vessels in the lung—can reverse the symptoms of emphysema. The study, which will be published July 21 in the Journal of Experimental Medicine (JEM), may lead to new treatments for chronic obstructive pulmonary disease (COPD), an inflammatory lung disease associated with smoking that is thought to be the third leading cause of death worldwide.
Public health measures designed to reduce the spread of the COVID-19 virus may have fostered a substantial side benefit: A 53 percent drop in hospital admissions for chronic obstructive pulmonary disease (COPD), likely due to a drop in circulating seasonal respiratory viruses such as influenza.
To lower hospital readmission rates for patients with chronic obstructive pulmonary disease (COPD), University at Buffalo pharmacy researcher David Jacobs has received a $962,000 award from the National Heart, Lung, and Blood Institute to develop a real-time readmission risk prediction algorithm.
Article title: Blockade of PD-1 decreases neutrophilic inflammation and lung damage in experimental COPD Authors Felix Ritzmann, Kai Borchardt, Giovanna Vella, Praneeth Chitirala, Adrian Angenendt, Christian Herr, Michael D. Menger, Markus Hoth, Annette Lis, Rainer M Bohle, Robert Bals, Christoph…
A UCLA-led study shows that physicians frequently order preventive medical services for adult Medicare beneficiaries that are considered unnecessary and of “low value” by the U.S. Preventive Services Task Force — at a cost of $478 million per year.
In a series of experiments that began with amoebas — single-celled organisms that extend podlike appendages to move around — Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.
A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.
NIH researchers and their collaborators found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of COPD. Hyaluronan is a sugar secreted by living tissue that acts as a scaffold for cells. Utilized as a treatment, hyaluronan decreased the number of days in the hospital.
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease that causes breathlessness, chronic sputum production and cough. There are 300 million current cases of COPD in the world. COPD is currently the third leading cause of death globally and is highly prevalent in low resource countries. Exposure to tobacco smoke and other inhaled toxic particles and gases are the main risk factors for COPD, although recent research has identified that suboptimal lung growth before and after birth can also increase the risk of COPD later in life.
The latest clinical practice guideline on home oxygen therapy addresses long-term and ambulatory oxygen therapy for adults with chronic obstructive pulmonary disease and interstitial lung disease and includes the most comprehensive review of the evidence of any oxygen guideline to date.
Babies born to mothers who smoked during pregnancy are more likely to suffer from impaired lung development. They are also more susceptible to developing lung diseases such as asthma and chronic obstructive pulmonary disease (COPD).
Today, the ATS Research Program announced three research grant opportunities with support from 4DMedical, a global medical technology company with a focus on lung health. With a total grant support of $150,000, each of the three $50,000 grants will fund research in asthma, chronic obstructive pulmonary disorder or COPD, and idiopathic pulmonary fibrosis or IPF.
A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).
A subcommittee of the American Thoracic Society Assembly in Sleep and Respiratory Neurobiology has released new clinical practice guidelines to help advise clinicians on the optimal management of patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. Hypercapnia is the buildup of carbon dioxide in the bloodstream.
In the midst of the extraordinary health challenge presented by the COVID-19 pandemic, Baylor Scott & White Health remains committed to quality, safe care and helping Texas communities navigate the uncertainty of the SARS-CoV-2 virus. Today, this commitment to safety and quality is recognized as U.S. News & World Report releases its 2020-2021 Best Hospitals list.
As we continue to grapple with the global pandemic, rising summer temperatures and wildfire season pose new challenges to our lung health. A team of pulmonologists and researchers at UC San Diego Health offer a wide variety of expertise and…
Asthma does not appear to increase the risk for a person contracting COVID-19 or influence its severity, according to a team of Rutgers researchers.
Researchers at The University of Kansas Cancer Center are studying vaping to better understand its effects on our health, as well as reduce vaping among adolescents.
While both sexes have the capacity for phenomenal athletic achievements, women on average must work harder to breathe during strenuous exercise compared to men, according to new research.
Clinicians grappling with the pharmacologic management of COPD in patients complaining of exercise intolerance or dyspnea now have new guidance. The American Thoracic Society has published an official clinical practice guideline in which a panel of experts strongly recommended LABA/LAMA combination therapy over LABA or LAMA alone. The complete guideline detailing all the recommendations was posted online ahead of print in the American Journal of Respiratory and Critical Care Medicine.
Because COVID-19 attacks the lungs, limiting social contact is extremely important for people who have underlying health conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and any additional chronic lung illness.
Once-daily treatment of patients with chronic obstructive pulmonary disease (COPD) with an inhaler combining fluticasone furoate (FF), umeclidinium (UMEC) and vilanterol (VI) reduced all-cause mortality by 42 percent, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
A UK study of patients participating in low-dose CT lung cancer screening highlights the importance of spirometry (breathing tests) in the assessment of possible chronic obstructive pulmonary disease (COPD), and demonstrates that over-reliance on radiological changes alone may result in detection of clinically insignificant disease. The new study is published online in the Annals of the American Thoracic Society.
Traditional stoves that burn biomass materials and are not properly ventilated, which are widely used in developing nations where cooking is done indoors, have been shown to significantly increase indoor levels of harmful PM2.5 (miniscule atmospheric particulates) and carbon monoxide (CO) and to stimulate biological processes that cause lung inflammation and may lead to chronic obstructive pulmonary disease (COPD), according to new research published online in the Annals of the American Thoracic Society.
In a new paper published Feb. 4 in JAMA, Mayo Clinic researchers describe the benefits of in-home noninvasive ventilation therapy ― which includes a type referred to as bilevel positive airway pressure, or BiPAP ― for many patients with chronic obstructive pulmonary disease (COPD). The team identified a number of benefits, including reduced mortality, fewer hospital admissions, lower risk of intubation, improved shortness of breath, and fewer emergency department visits.
ResMed (NYSE: RMD, ASX: RMD) and ATS Foundation have awarded their third $100,000 Research Fellowship grant to Claude Farah, PhD, of the Woolcock Institute of Medical Research in Sydney, Australia, to study how remote monitoring can help improve the management of patients with chronic obstructive pulmonary disease, or COPD.
Dransfield said their findings showed no evidence that beta-blockers were helpful in reducing the risk of exacerbations.
In a new study, researchers at Intermountain Healthcare in Salt Lake City found that steps measured through a step tracker worn on the wrist can be used to estimate exercise capacity and determine the health status of patients, rather than the standardized six-minute walk distance test, which is usually conducted in a clinical setting.