In their lab, CRCHUM scientists Emmanuelle Brochiero and Damien Adam are studying ways of better predicting the efficacy of medications and helping injured lungs repair and regenerate.
Article title: Androgen receptor activation alleviates airway hyperresponsiveness, inflammation and remodeling in a murine model…
Article title: Blockade of PD-1 decreases neutrophilic inflammation and lung damage in experimental COPD Authors…
A phase 3 clinical trial finds an anti-inflammatory drug used in rheumatoid arthritis can preserve lung function in patients with systemic sclerosis.
Findings should empower the search for better treatments for lung diseases
Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially treat the deadly, aging-related lung disease idiopathic pulmonary fibrosis (IPF). The study, which will be published March 10 in the Journal of Experimental Medicine (JEM), suggests that targeting a protein called MDM4 could prevent respiratory failure by initiating a genetic program that removes scar tissue from the lungs.
Scientists at Washington University School of Medicine in St. Louis have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection. The evidence suggests that activation of this immune cell serves as an early switch that, when activated, drives progressive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
To mark Rare Disease Day on February 28, the Pulmonary Fibrosis Foundation (PFF) aims to increase public understanding of pulmonary fibrosis (PF) to drive home the importance of early diagnosis to help improve the quality of life for patients.
Rockville, Md. (February 11, 2021)—The popularity of e-cigarettes continues to grow, especially among children and…
New research shows chocolate-flavored e-cigarettes are “particularly harmful” to the lungs.
A new study published in the Environmental Health Perspectives connects insulin resistance and repetitive ozone exposure to the development of interstitial lung disease.
University of Miami Health System and 4DMedical Launch Research Program Advancing Breakthrough Lung Technology
UHealth – the University of Miami Health System, the University of Miami Leonard M. Miller School of Medicine, and 4DMedical recently announced the creation of the Functional Lung Imaging Research Program in the Department of Medicine’s Division of Pulmonary, Critical Care and Sleep Medicine at the Miller School.
Article title: Bacterial extracellular vesicles isolated from organic dust induce neutrophilic inflammation in the lung…
A new study published online in the Annals of the American Thoracic Society reveals how patients hospitalized with severe COVID-19 fared, compared to those hospitalized with severe seasonal influenza. The study is believed to be the first in the U.S. to directly compare clinical features, laboratory results and health outcomes between patients with the two diseases.
The Pulmonary Fibrosis Foundation today announced the “Pinpoint PF” education and awareness campaign aimed at individuals with symptoms and at a higher risk for pulmonary fibrosis (PF).
New research published in the journal Function identifies NKCC1, the protein responsible for moving sodium,…
A new study in mice explores the effect of aging on the regenerative properties of lung cells after lung injury. The study is published in the American Journal of Physiology-Lung Cellular and Molecular Physiology. It was chosen as an APSselect article for November.
October is Healthy Lung Month, an apt time to educate the public about the importance of protecting our lungs against mold, airborne pollutants and smoking – which put hundreds of thousands of Americans at higher risk for pulmonary fibrosis (PF).
A new review suggests “heat-not-burn” tobacco devices may threaten cardiovascular health. The review is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology.
Babies born to mothers who smoked during pregnancy are more likely to suffer from impaired lung development. They are also more susceptible to developing lung diseases such as asthma and chronic obstructive pulmonary disease (COPD).
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries. The findings, which were published today in Nature Cell Biology, could lead to better therapies for patients with lung disease, including acute respiratory distress syndrome (ARDS) due to COVID-19.
September’s Pulmonary Fibrosis Awareness Month shares crucial realities and insights about the rare disease, its symptoms and helpful resources provided by the Pulmonary Fibrosis Foundation to educate the public about this devastating disease which impacts over 200,000 Americans.
The ATS Research Program is pleased to announce the new ATS/CSL Behring Research Award in Acute Respiratory Distress Syndrome or ARDS. The award will provide $50,000 in funding for one year.
A subcommittee of the American Thoracic Society Assembly in Sleep and Respiratory Neurobiology has released new clinical practice guidelines to help advise clinicians on the optimal management of patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. Hypercapnia is the buildup of carbon dioxide in the bloodstream.
NIH has launched an ambitious effort to use artificial intelligence, computation, and medical imaging to enable early disease detection, inform successful treatment strategies, and predict individual disease outcomes of COVID-19.
Join us on Aug. 5-10 2020 for ATS 2020 Virtual, when the American Thoracic Society will host a mix of live and pre-recorded sessions in pulmonary, critical care, and sleep medicine. Press are invited to attend (see press guidelines) and may register now. Same day registration will be available during the meeting.
Smoking and vaping-related lung injuries create an underlying medical condition that can make people more…
Chest X-Rays in Emergency Rooms Can Help Predict Severity of COVID-19 Illness in Young and Middle-aged Adults
Chest X-rays performed on young and middle-aged adults with COVID-19 when they arrive at the emergency room can help doctors predict who is at higher risk of severe illness and intubation, Mount Sinai researchers report.
Early reports of COVID-19 symptoms and the compelling need to quickly identify treatment options and curb the growing number of critically ill patients have led to erroneous and potentially dangerous comparisons between COVID-19 and other respiratory diseases like high altitude pulmonary edema, or HAPE.
New guidance is available for physicians who must go through a number of steps to provide a probable diagnosis of sarcoidosis – an inflammatory disease that affects the lungs, lymph glands, and other organs.
A new review suggests that higher-than-normal levels of an enzyme involved in blood clot prevention may be a common risk factor for developing COVID-19—a respiratory disease caused by the novel coronavirus SARS-CoV-2—in some populations. The review is published in Physiological Reviews.
Rapidly escalating numbers of COVID-19 patients suffering from respiratory failure threaten to overwhelm hospital capacity and force healthcare providers into making challenging decisions about the care they provide. Of particular interest is the role of ECMO – extracorporeal membrane oxygenation, a form of life support for patients with advanced lung disease – to support critically ill patients in the current pandemic.
Coronavirus’ Binding Action May Also Cause Kidney Damage and Infertility; Researchers Consider Potential Treatment Paths
Article title: COVID-19 infection and mortality – A physiologist’s perspective enlightening clinical features and plausible…
Mount Sinai Physicians the First in U.S. Analyzing Lung Disease in Coronavirus (COVID-19) Patients from China
Findings from CT scans provide new insight that could lead to quicker diagnosis
Article title: Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway…
‘Are Noncommunicable Diseases Communicable?’ Rutgers Experts Available to Discuss Paper in Science Today
New Brunswick, N.J. (Jan. 16, 2020) – Rutgers professors Maria Gloria Dominguez-Bello and Martin J. Blaser…
The number of people newly infected each year and the number of people living with nontuberculous mycobacterial lung disease appears to be increasing, especially among women and those 65 and older, according to new research published online in the Annals of the American Thoracic Society.
New research in mice suggests that exposure to antibiotics before birth may impair lung development in premature infants. The study, the first to explore the gut-lung axis in prematurity, is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology and was chosen as an APSselect article for December.
A new study finds that e-cigarette vapor weakens the mobility and function of immune cells designed to fight infection. This reduced ability may increase the risk of bacterial illnesses in people who vape. The research is published ahead of print in the American Journal of Physiology—Cell Physiology.
Mount Sinai Researchers Develop Novel Method to Identify Patterns Among Patients With Multiple Chronic Conditions
A study by researchers at Icahn School of Medicine at Mount Sinai proposes a novel method for identifying patterns in the frequency and cost of multiple chronic conditions (MCC).
WHO: Keith S. Naunheim, MD, Vallee L. Melba Willman Professor and Chief of Cardiothoracic Surgery…