Article title: The matricellular protein CCN3 supports lung endothelial homeostasis and function Authors: Kalpana R. Betageri, Patrick A. Link, Andrew J. Haak, Giovanni Ligresti, Daniel J. Tschumperlin, Nunzia Caporarello From the authors: “Altogether, our results demonstrate that the matricellular protein…
Tag: Lung Function
Many Black Men with “Normal” Lung Function May Actually Have Emphysema
A significant percentage of Black men found to have normal lung function after race-based adjustments to spirometry were actually found to have emphysema on their computed tomography (CT) scans, according to research published at the ATS 2022 international conference.
Repurposing Tocilizumab in Scleroderma Patients May Prevent Early Lung Disease
A phase 3 clinical trial finds an anti-inflammatory drug used in rheumatoid arthritis can preserve lung function in patients with systemic sclerosis.

Quit the Hookah! Lung Damage, Inflammation Is Reversible with Smoking Cessation
New research finds that quitting smoking is an effective way to resolve impaired lung function and airway inflammation associated with waterpipe smoking. The study is published ahead of print in the American Journal of Physiology-Lung Cellular and Molecular Physiology.
Low Oxygen-related Inflammation Leads to More Platelets in Mouse Lungs
Article title: Platelet activation contributes to hypoxia-induced inflammation Authors: Cassidy Delaney, Pavel Davizon-Castillo, Ayed Allawzi, Janelle Posey, Aneta Gandjeva, Keith Neeves, Rubin M. Tuder, Jorge Di Paola, Kurt R. Stenmark, Eva S. Nozik From the authors: “Our data provide evidence…

Exercised Over Nothing: Masks Don’t Impair Lung Function During Physical Activity
A team of American and Canadian researchers report that while they may feel uncomfortable, there is little empirical evidence that wearing a facemask significantly diminishes lung function, even when worn during heavy exercise.
Increased Oxygen Concentration in Inhaled Air Helps Coronavirus Enter the Body
Article title: Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium Authors: Despoina Myti, Miša Gunjak, Francisco Casado, Solmaz Khaghani Raziabad, Claudio Nardiello, István Vadász, Susanne Herold, Gloria Pryhuber, Werner Seeger, Rory E. Morty From the authors: “The data presented here…
Link Found Between Pet Ownership and Health
Research found that pet ownership improves health in some instances, but increases risk in others.

Wuhan Study is First to Describe How Body Positioning Can Improve Breathing in Severe COVID-19 Patients Requiring Ventilation
In a new study of patients with severe COVID-19 (SARS-CoV-2) hospitalized on ventilators, researchers found that lying face down was better for the lungs. The research letter was published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

ResMed, ATS Foundation Award $100,000 Research Grant to Claude Farah, PhD
ResMed (NYSE: RMD, ASX: RMD) and ATS Foundation have awarded their third $100,000 Research Fellowship grant to Claude Farah, PhD, of the Woolcock Institute of Medical Research in Sydney, Australia, to study how remote monitoring can help improve the management of patients with chronic obstructive pulmonary disease, or COPD.
Study Identifies Genetic Anomaly Associated with Poor Response to Common Asthma Treatment
A new Cleveland Clinic study has uncovered a genetic anomaly associated with poor response to a common asthma treatment. The findings, published in Proceedings of the National Academy of Sciences, showed that asthmatic patients with the gene variant are less likely to respond to glucocorticoids and often develop severe asthma.
FDA approves drug that improves lung function in most Cystic fibrosis patients.
Steve Rowe, M.D., professor of medicine at the University of Alabama at Birmingham and director of the Gregory Fleming James Cystic Fibrosis Research Center, is available to discuss the FDA approval of Trikafta, a new triple combination therapy for CF. …