Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.
Using anonymized medical records from a national registry, UC San Diego researchers confirm earlier findings that statins may substantially minimize adverse outcomes from SARS-CoV-2 infection.
A new study out of UChicago found that while 43 states (out of 51, including all 50 states and Washington, D.C.) created a committee to develop a vaccine distribution plan, only 20 plans mentioned using a health equity committee to assist with plan development.
Researchers have found that viral vaccines grown in eggs, such as the H1N1 flu vaccine, produce an antibody response against a sugar molecule found in eggs, which could have implications for the effectiveness of these vaccines.
How common COVID-19 is among infants may depend on the degree of the pandemic virus circulating in a community, a new study finds.
UC San Diego Health is now offering a verifiable digital vaccine record to its patients who have or will receive a COVID-19 vaccine. These secure online records, otherwise known as a SMART health card, can be accessed directly from the MyUCSDChart patient portal.
MADISON – The presence of a state prison in a county was associated with 11% more COVID-19 cases through July 1, 2020, according to a new study from the University of Wisconsin–Madison.
UNC-Chapel Hill scientists investigated blood samples from children enrolled in a dengue vaccine trial to identify the specific kinds of antibody responses that correlate with protection against dengue virus disease.
A groundbreaking study found that stem cells reduce the amount of virus causing AIDS, boost the body’s antiviral immunity, and restore the gut’s lymphoid follicles damaged by HIV. It provided a roadmap for multi-pronged HIV eradication strategies.
Scientists have a general idea of how viruses invade and spread in the body, but the precise mechanisms are actually not well understood, especially when it comes to Ebola virus. Olena Shtanko, Ph.D., a Staff Scientist at the Texas Biomedical Research Institute (Texas Biomed), has received more than $1 million from the National Institutes of Health (NIH) to explore different aspects of Ebola virus infection.
New York City neighborhoods that had higher levels of socioeconomic disadvantage experienced more COVID-19 infections and deaths, according to Mount Sinai scientists who created a neighborhood-level COVID-19 inequity index.
The IDSA Foundation announces a call for applications for the 2021 Microbial Pathogenesis in Alzheimer’s Disease Grant. The $1.7 million grant, an increase from $1 million in 2020, will fund the advancement of novel research into possible links between infectious diseases and the causation of Alzheimer’s disease.
A multinational effort is underway to understand and control the spread of disease among migratory birds.
Abstract: Disease-specific COVID-19 pediatric comorbidity has not been studied effectively todate. Atopy and food anaphylaxis disease states require improved characterization of SARS-CoV-2 infection risk. To provide the first such characterization, we assessed serum samples of a highlyatopic, food anaphylactic, asymptomatic…
A coalition of six U.S. subsidiary companies have sponsored a COVID-19 mobile clinic to vaccinate 10,000 maquiladora workers employed in Baja California, Mexico. UC San Diego Health is vaccinating about 1,500 workers daily.
The discovery of new possible biomarkers to predict clinical and immune responses to dengue virus infection could be critical to informing future vaccines for the mosquito-borne virus, which saw a record number of over 400 million cases in 2019.
Within the next decade, the novel coronavirus responsible for COVID-19 could become little more than a nuisance, causing no more than common cold-like coughs and sniffles. That possible future is predicted by mathematical models that incorporate lessons learned from the current pandemic on how our body’s immunity changes over time. Scientists at the University of Utah carried out the research, now published in the journal Viruses.
University of Miami Miller School of Medicine researchers report the widespread blood vessel dysfunction, or endothelial dysfunction, that results from the COVID-19 infection could contribute to erectile dysfunction, or ED, according to a study published in the World Journal of Men’s Health .
Published in the journal Proceedings of the Royal Society B, the research analyzes more palatable alternatives to the kind of social distancing mandates that threw a wrench at how businesses, schools and even family gatherings work.
After COVID-19 emerged on U.S shores, providers began reviewing the emerging basic science, translational, and clinical data to identify potentially effective treatment options. In addition, a multitude of both novel and repurposed therapeutic agents were used empirically and studied within clinical trials.
UC San Diego School of Medicine researchers discovered one way in which SARS-CoV-2 hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.
Because COVID-19 has been detected in urine and stool samples, public restrooms can be cause for concern. Researchers measured droplets generated from flushing a toilet and a urinal in a public restroom and found a substantial increase in the measured aerosol levels in the ambient environment with the total number of droplets generated in each flushing test ranging up to the tens of thousands. Due to their small size, these droplets can remain suspended for a long time.
As California opens up COVID-19 vaccination eligibility to everyone age 16 and older, UC San Diego Health sports medicine specialists Samuel Galloway, MD, and Alan Shahtaji, DO, are available to discuss what people should know about exercise before and after vaccination. Sample topics: Exercise…
UC San Diego researchers found that the chemical inhibitor K777 reduces the coronavirus’ ability to infect cell lines by blocking human enzyme cathepsin L; clinical trials are underway.
UC San Diego students will participate in nationwide clinical trial to assess if COVID-19 vaccination prevents infection and reduces risk of transmission.
The most recent data available suggests reported cases of sexually transmitted diseases (STDs) have declined. This is good news, but experts at University of California San Diego AntiViral Research Center say STD rates could soon be on the rise again.…
UC San Diego researchers discovered that patient survival from sepsis is associated with higher platelet counts, and identified two currently available drugs that protect these blood cells and improve survival in mice with sepsis.
Investigators from UC San Diego and UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus. Risk of infection is minuscule, but exists.
A new research study at the University of Chicago Medicine has found that when it comes to COVID-19, having vitamin D levels above those traditionally considered sufficient may lower the risk of infection, especially for Black people.
Using molecular dating tools and epidemiological simulations, researchers at UC San Diego School of Medicine estimate that the SARS-CoV-2 virus likely circulated undetected for two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.
A Michigan Medicine team’s online guidelines have been viewed more than 30,000 times by providers in 150 countries since the beginning of the pandemic–and their deployment of an effective COVID-19 therapy has been a model for health systems and hospitals statewide.
Nursing homes with the largest proportions of non-White residents experience 3.3 times more COVID-19 deaths than do nursing homes with the largest proportions of White residents, according to a new study from the University of Chicago.
UC San Diego School of Medicine researchers develop an automated process to test city sewage for SARS-CoV-2, allowing them to forecast the region’s COVID-19 caseload one to two weeks ahead of clinical diagnostic reports.
A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.
UC San Diego was awarded five COVID-19 Rapid Acceleration of Diagnostics (RADx) projects by the National Institutes of Health totaling nearly $33 million, which will fund efforts that range from managing a large data center to expanding testing in disadvantaged communities.
There is now keen interest in deeper investigation of infectious agents as the trigger of Alzheimer’s disease
UC San Diego researchers report that individual immune response to SARS-CoV-2 may be limited by a set of variable genes that code for cell surface proteins essential for the adaptive immune system. The finding may help explain why COVID-19 immunity varies by individual.
University of Miami Miller School of Medicine researchers are recruiting health care workers to study whether a wearable device, a wristwatch, can capture real time data that can be used to alert wearers of subtle physiological changes that may indicate they have become infected with COVID-19.
In an effort to help schools reduce the risk of COVID-19 outbreaks as they resume in-person instruction, UC San Diego and the County of San Diego are testing the Safer at School Early Alert system to detect SARS-CoV-2 at schools and child care centers.
Rush University Medical Center is opening an advanced molecular laboratory that will examine COVID-19 samples from across the city to detect new strains of the virus for the Chicago Department of Public Health
The National Italian American Foundation (NIAF) is now accepting applications for the inaugural class of Fauci Fellowships, created in recognition of Dr. Anthony S. Fauci’s contributions to humanity and the medical and scientific community.
UC San Diego researchers find that an optical tool already embedded in many smartphones can accurately diagnose blood-oxygen levels and help monitor respiratory disease in patients, particularly when they are quarantined at home.
The 2019-2020 flu season in the U.S. was unusual in a number of ways. Cases picked up in August rather than the more typical fall and early winter months, and it hit children particularly hard.
Cedars-Sinai has launched the COVID-19 Recovery Program to meet the needs of a growing number of COVID-19 patients who experience lingering symptoms weeks and even months after physicians say they are virus-free.
CLEVELAND: As part of the new Cleveland Innovation District announced today by State of Ohio Governor Mike DeWine, Lieutenant Governor Jon Husted, JobsOhio and Ohio Development Services Agency, Cleveland Clinic will significantly expand its global commitment to infectious disease research and translational programs to form the Global Center for Pathogen Research & Human Health.
The new Center will position Ohio as an international leader for research into emerging pathogens and virus-related diseases and will serve as a significant economic catalyst in Northeast Ohio. Funding comes through a $500 million investment from the State of Ohio, JobsOhio and Cleveland Clinic.
Even as vaccinations against COVID-19 are under way, the virus continues to kill thousands of Americans every day, making it more important than ever to stay safe and be ready in case it strikes you or your family. Here’s what you need to do to prevent and prepare for the novel coronavirus.
Wildfire smoke contains microbes, infectious agents that might cause diseases. In a perspective piece published in Science, researchers at UC Davis Health and the University of Idaho proposed a multidisciplinary approach to study the health impacts of microbes carried by wildfire smokes.
Moderate temperature increases broke down SARS-CoV-2 virus-like particles structure on glass surfaces, suggesting that virus particles on surfaces will remain infectious longer. The findings agree with observations of other coronaviruses that appear to infect more people during the winter.
Hospital-based laboratories and doctors at the front line of the COVID-19 pandemic might soon add artificial intelligence to their testing toolkit. A recent study describes the performance of Biocogniv’s new AI-COVID™ software, which showed high accuracy in predicting the probability of COVID-19 infection using routine blood tests, which can help hospitals reduce the number of patients referred for scarce PCR testing.