You might have heard or read about the ‘superbug’ Candida auris (C. auris), but is it as scary as the news makes it seem?
Tag: Infectious Disease
Why Subvariants of the SARS-CoV-2 Virus Accelerated the Pandemic
UC San Diego researchers describe why SARS-CoV-2 subvariants spread more rapidly than the original virus strain, and how an early treatment might have made people more susceptible to future infections.
A Quick New Way to Screen Virus Proteins for Antibiotic Properties
A whole new world of antibiotics is waiting inside the viruses that infect bacteria. Our scientists are making it easier to study them.
New $17 million grant establishes LJI as global hub for immunology data curation and analysis
A new grant of over $17 million from the National Institute of Allergy and Infectious Diseases (NIAID) has established La Jolla Institute for Immunology (LJI) as the leading institute for human immunology data curation, analysis, and dissemination. With this funding, LJI has taken the helm of the Human Immunology Project Consortium Data Coordinating Center, a critical tool in the effort to fuel scientific collaboration in immunoprofiling and highlight findings from the overall Human Immunology Project Consortium (HIPC).
UT Southwestern biochemist, molecular biologist to receive HHMI Emerging Pathogens awards
Two of UT Southwestern’s Howard Hughes Medical Institute researchers in biochemistry and molecular biology will lead separate teams as part of HHMI’s Emerging Pathogens Initiative (EPI) targeting infectious diseases that pose a threat to human health.
Host-Cell Factors Involved in COVID-19 Infections May Augur Improved Treatments
Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.
International policy adviser, epidemiologist Dr. Saad Omer selected inaugural dean for UT Southwestern’s O’Donnell School of Public Health
Internationally recognized epidemiologist Saad B. Omer, M.B.B.S, Ph.D., who currently directs the Yale Institute for Global Health, has been appointed the inaugural Dean of the Peter O’Donnell Jr. School of Public Health at UT Southwestern Medical Center.
UTSW Pharmacologist James Collins receives 2023 TAMEST Edith and Peter O’Donnell Award
James Collins III, Ph.D., Associate Professor of Pharmacology at UT Southwestern Medical Center, will receive the 2023 Edith and Peter O’Donnell Award in Biological Sciences from The Academy of Medicine, Engineering and Science of Texas (TAMEST) for broadening understanding of schistosomiasis.
Increasing Robo4 expression may help with infections
The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression. When the researchers treated LPS-injected mice with a drug that inhibits ALK1-SMAD signaling, they observed increased Robo4 expression, decreased vascular permeability, and reduced mortality.
Japan’s lack of infectious diseases research exposed by COVID-19 pandemic
Japan’s government has drawn criticism from some of the nation’s researchers following a new analysis that shows Japan has for years been lagging in the field of infectious diseases research, including after the COVID-19 pandemic had hit.
LJI Instructor Annie Elong Ngono, Ph.D., wins GVN support to advance infectious disease research
LJI Instructor Annie Elong Ngono, Ph.D., has spearheaded important studies into the immune response to deadly pathogens such as dengue virus. Now, this dedication to global health and virology has earned her acceptance to the Global Virus Network’s (GVN) highly selective Rising Star Mentorship Program.
LJI scientists confirm smallpox vaccine also teaches T cells to fight mpox
“Vaccines such as JYNNEOS should be able to induce T cells that also recognize mpox and can provide protection from severe disease.”
Flu shots are recommended for those 65 and older as cases rise
With flu cases on the rise, geriatric specialists at UT Southwestern Medical Center say vaccinations are particularly important this year for people 65 and older who are more at risk from complications than other age groups.
Say Goodbye to Fish Vaccine Injection with “FLAVO INNOVAC” Nano Vaccine for Immersion : The Effective Solution for Prevention of Bacterial Gills Diseases in Fish caused by Flavobacterium spp.
A lecturer and his research team from Faculty of Veterinary Science, Chulalongkorn University, have developed “FLAVO INNOVAC” nanovaccine for the prevention of bacterial gills diseases in freshwater fish species such as Tilapia and freshwater Asian sea bass. This nanovaccine is an effective solution that reduces the risk of death from diseases and the limitations of vaccine injections.
The cell sentinel that neutralises hepatitis B
The hepatitis B virus (HBV) is responsible for one of the most serious and common infectious diseases. Transmitted through biological fluids, it attacks the liver cells.
The longer the bootcamp, the better the antibodies
LJI research shows that a “slow delivery, escalating dose” vaccination strategy can prompt B cells to spend months mutating and evolving their pathogen-fighting antibodies.
University Hospitals Chosen as Site for United States Flu Vaccine Effectiveness Network
The Center for Disease Control’s National Center for Immunization and Respiratory Diseases has awarded University Hospitals of Cleveland a sizable grant to support its assignment as a study site in the United States Flu Vaccine Effectiveness Network.
How human cells become Zika virus factories
Scientists solve mystery of how Zika virus targets key immune cell. New finding shed light on how to stop virus from spreading.
Tulane working on test to predict COVID-19 complications
An interdisciplinary team of doctors and engineers are working to develop a diagnostic test to detect severe COVID-19 complications.
Cancer and HIV
Sylvester Comprehensive Cancer Center researcher Emmanuel Thomas, M.D., Ph.D., F.A.A.S.L.D., has been appointed to the National Institutes of Health’s (NIH) Coinfections and HIV Associated Cancers (HCAC) study section.
How Wastewater Surveillance Can Mitigate Monkeypox Spread: Expert Available
Just when it seemed like we could sit back and breathe a sigh of relief from declining COVID-19 rates in Nevada, another virus started making headlines: Monkeypox. Local COVID cases have been on a downward trajectory for more than a month. But a wastewater surveillance program led by UNLV Kirk Kerkorian School of Medicine professor and infectious disease expert Edwin Oh has started tracking monkeypox,making Southern Nevada among the first few metropolitan areas nationwide to begin searching the sewers for the emerging virus.
Infectious Disease Expert Available to Address Recent Polio Case and Increase in Monkeypox Cases
Sandra A. Kemmerly, MD, MACP, FIDSA joined the Ochsner staff in 1988 and is board certified in both internal medicine and infectious diseases. She maintains an active practice and is the clinical lead for Ochsner Healths Covid response in addition…
Dr. Baumgarten Available to Address Recent Polio Case and Increase in Monkeypox Cases
Dr. Baumgarten currently serves as Medical Director of Infection Control and Prevention for Ochsner Health since 2008, during which time she been involved in preventing transmissible diseases in the Ochsner System and our community. Over the past two years, she…
Disparities in United States COVID-19 Vaccine Distribution
Health care facilities in Black metropolitan counties, Hispanic rural counties and hardest-hit counties were less likely to administer COVID-19 vaccines during initial rollout, UC San Diego study finds.
Post-COVID Lung Disease Shares Origins with Other Scarring Lung Disorders
UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.
Mayo Clinic Laboratories launches monkeypox test to increase access, availability
Mayo Clinic Laboratories can now test for monkeypox, a rare viral infection, using the Centers for Disease Control and Prevention’s (CDC) orthopoxvirus test kit.
Awash in Potential: Wastewater Provides Early Detection of SARS-CoV-2 Virus
Scientists and physicians at UC San Diego and Scripps Research describe how wastewater sequencing provided dramatic new insights into levels and variants of SARS-CoV-2 on campus and in the broader community — a key step to public health interventions in advance of COVID-19 case surges.
Familiarity Breeds Exempt: Why Staph Vaccines Don’t Work in Humans
UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.
Columbia University & CDC Partner With Zambian Scientists to Prevent Pandemics
Columbia University’s Global Alliance for Preventing Pandemics announces an agreement with the University of Zambia’s School of Veterinary Medicine and the U.S. Center for Disease Control and Prevention to train Zambian public health professionals to better identify and contain pathogen outbreaks.
Targeting a human protein to squash SARS-CoV-2 and other viruses
In ACS Infectious Diseases, scientists now report that apratoxin S4, an anticancer drug candidate that targets a human protein, can interfere with the replication of many viruses, including SARS-CoV-2 and influenza A, offering a possible pan-viral therapy.
Wastewater Surveillance for COVID-19: It’s Complicated
Elena Naumova, professor at the Friedman School of Nutrition Science and Policy at Tufts University, explains wastewater surveillance and testing, the underlying process and the pros and cons of its use.
COVID-19 Rebound after Taking Paxlovid Likely Due to Insufficient Drug Exposure
COVID-19 rebound following Paxlovid treatment likely due to insufficient drug exposure, UC San Diego researchers find after showing rebound patient did not show drug resistance or impaired immunity.
Kawasaki Disease Rates Dropped During COVID-19 Pandemic
UC San Diego researchers report significant decrease in national cases of Kawasaki disease during COVID-19 pandemic; findings hint at origins of disease.
COVID-19 on the Brain: Neurological Symptoms Persist in Majority of Long-Haulers
A UC San Diego study describes the short- and long-term neurological symptoms of SARS-CoV-2 infection, and identifies a new group of COVID-19 long-haulers with advanced motor and cognitive symptoms.
What Do We Know – and Need to Know – About Monkeypox?
Q&A about monkeypox with Dr. Anne Rimoin, UCLA Fielding School of Public Health professor of epidemiology and the Gordon-Levin Endowed Chair in Infectious Diseases and Public Health, has been studying monkeypox for two decades.
Infectious disease doctor answers questions about the monkeypox virus
The growing concern of recent outbreaks of the rare monkeypox virus reported in the U.S. and abroad have health authorities monitoring transmission rates and keeping a close eye on the emerging issue. Charles Schleupner, a professor of internal medicine who…
The US reaches 1 Million Deaths from COVID-19: GW Experts Available to Comment
The United States has reached 1 million reported deaths from COVID-19 and that number is likely an undercount, according to the Centers for Disease Control and Prevention. The George Washington University has a number of experts to comment on the…
COVID-19, MIS-C and Kawasaki Disease Share Same Immune Response
COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.
Dr. Anne Rimoin Named to new Gordon–Levin Chair in Infectious Diseases and Public Health at UCLA Fielding School of Public Health
Dr. Anne Rimoin, an internationally recognized expert on emerging infections, global health, infectious disease surveillance systems and vaccinations who has been engaged in pandemic preparedness and response work for more than two decades, has been appointed to the newly established Gordon–Levin Endowed Chair in Infectious Diseases and Public Health at the UCLA Fielding School of Public Health.
Virtual Village Treats HIV-associated Loneliness in Novel UC San Diego Health Trial
A new trial by UC San Diego Health infectious disease specialist Maile Young Karris, MD, will use longitudinal questionnaires and qualitative interviews to assess the impact of living in an interconnected virtual village on the loneliness known to afflict older people with HIV.
Hepatitis A Vaccination Required for Herd Immunity in People Experiencing Homelessness or Who Use Drugs
In the U.S., hepatitis A outbreaks are repeatedly affecting people experiencing homelessness or who use drugs. A 2017-19 Kentucky outbreak primarily among these groups resulted in 501 cases, six deaths. Vaccination efforts likely averted 30 hospitalizations and $490K in costs,…
Pregnant Women Who Receive COVID-19 Vaccination Pass Protection from the Virus to Their Newborns
Women who receive COVID-19 mRNA vaccines during pregnancy pass high levels of antibodies to their babies, a new NYU Langone study finds.
Hospital AI Learns to Say ‘I Don’t Know’
Sepsis occurs when the body works so hard to fight an infection that the immune system injures the patient’s own tissues. Detecting sepsis early and delivering antibiotics promptly is key to saving lives. UC San Diego Health researchers developed an…
Infection detection: DNA researchers develop critical shortcut to detect and identify known and emerging pathogens
Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause sepsis, among other uses.
3D analysis of SARS-CoV-2 reveals clues on virus tactics
The most comprehensive analysis of the 3D structure of SARS-CoV-2 to date has revealed new insight on how the virus infects human cells and replicates.
Study: No Serious COVID-19 Vaccine Side Effects in Breastfeeding Moms, Infants
Researchers found that breastfeeding mothers who received either the Pfizer-BioNTech or Moderna vaccination reported the same local or systemic symptoms as what has been previously reported in non-breastfeeding women, with no serious side effects in the breastfed infants.
Valley Fever more common in Utah than previously thought, researchers find
A new research study reveals that Valley Fever, a fungal disease most commonly found in Arizona and California, may be more common in Utah than previously thought.
With Time and Without Masks, COVID-19 Vaccines Wane in Protection
A study measured effectiveness of COVID-19 mRNA vaccines among health workers, most notably during the emergence of delta virus variant and coincident with end of state’s mask mandate, finding protection waned over time, dropping sharply 6-8 months after full vaccination.
2VIDA! Tackles COVID Vaccine Hesitancy and Barriers in Latinx, Black Communities
UC San Diego is collaborating with San Ysidro Health on an NIH-funded outreach program to address COVID-19 vaccine hesitancy in Latinx and African American communities. The team runs pop-up vaccination sites across San Diego, and goes door-to-door to homes and local businesses to spread awareness.
Symptomatic COVID patients are more contagious
Individuals with COVID-19 are most likely to spread the virus to close contacts two days before the onset of symptoms to three days after symptoms appear, and the risk of transmission is highest when patients had mild or moderate disease severity, according to a new study by researchers at the University of Georgia.