The United States has reached 1 million reported deaths from COVID-19 and that number is likely an undercount, according to the Centers for Disease Control and Prevention. The George Washington University has a number of experts to comment on the…
COVID-19, MIS-C and KD all share a similar underlying mechanism involving the over-activation of particular inflammatory pathways, UC San Diego study shows. Findings support novel drug targets for MIS-C.
Dr. Anne Rimoin, an internationally recognized expert on emerging infections, global health, infectious disease surveillance systems and vaccinations who has been engaged in pandemic preparedness and response work for more than two decades, has been appointed to the newly established Gordon–Levin Endowed Chair in Infectious Diseases and Public Health at the UCLA Fielding School of Public Health.
A new trial by UC San Diego Health infectious disease specialist Maile Young Karris, MD, will use longitudinal questionnaires and qualitative interviews to assess the impact of living in an interconnected virtual village on the loneliness known to afflict older people with HIV.
In the U.S., hepatitis A outbreaks are repeatedly affecting people experiencing homelessness or who use drugs. A 2017-19 Kentucky outbreak primarily among these groups resulted in 501 cases, six deaths. Vaccination efforts likely averted 30 hospitalizations and $490K in costs,…
Women who receive COVID-19 mRNA vaccines during pregnancy pass high levels of antibodies to their babies, a new NYU Langone study finds.
Sepsis occurs when the body works so hard to fight an infection that the immune system injures the patient’s own tissues. Detecting sepsis early and delivering antibiotics promptly is key to saving lives. UC San Diego Health researchers developed an…
Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause sepsis, among other uses.
The most comprehensive analysis of the 3D structure of SARS-CoV-2 to date has revealed new insight on how the virus infects human cells and replicates.
Researchers found that breastfeeding mothers who received either the Pfizer-BioNTech or Moderna vaccination reported the same local or systemic symptoms as what has been previously reported in non-breastfeeding women, with no serious side effects in the breastfed infants.
A new research study reveals that Valley Fever, a fungal disease most commonly found in Arizona and California, may be more common in Utah than previously thought.
A study measured effectiveness of COVID-19 mRNA vaccines among health workers, most notably during the emergence of delta virus variant and coincident with end of state’s mask mandate, finding protection waned over time, dropping sharply 6-8 months after full vaccination.
UC San Diego is collaborating with San Ysidro Health on an NIH-funded outreach program to address COVID-19 vaccine hesitancy in Latinx and African American communities. The team runs pop-up vaccination sites across San Diego, and goes door-to-door to homes and local businesses to spread awareness.
Individuals with COVID-19 are most likely to spread the virus to close contacts two days before the onset of symptoms to three days after symptoms appear, and the risk of transmission is highest when patients had mild or moderate disease severity, according to a new study by researchers at the University of Georgia.
Each wave of the pandemic has underscored just how gravely contagious COVID-19 is, but there is less clarity among experts on exactly when—and to what extent—infected individuals are most likely to spread the virus.
Part of UC San Diego’s Return to Learn program, wastewater screening helped prevent outbreaks by detecting 85 percent of cases early, allowing for timely testing, contact tracing and isolation.
UC San Diego Health physicians describe first known case of young, healthy adult experiencing central nervous system inflammation due to COVID-19, but without cognitive impairment.
A licensed drug normally used to treat abnormal levels of fatty substances in the blood could reduce infection caused by the SARS-CoV-2 virus by up to 70 per cent, reveals a study in the laboratory by an international collaboration of researchers.
UC San Diego researchers report that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.
The COVID-19 vaccine is your best defense against the virus, but when and where should you continue to wear a mask? Rush infectious disease expert Michael Lin, MD, answers questions about wearing a mask post-vaccination.
UC San Diego researchers modify remdesivir, creating oral version that can be taken earlier in COVID-19 diagnoses. In cell and animal studies, revised drug proved effective and safe.
Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.
Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.
Using anonymized medical records from a national registry, UC San Diego researchers confirm earlier findings that statins may substantially minimize adverse outcomes from SARS-CoV-2 infection.
A new study out of UChicago found that while 43 states (out of 51, including all 50 states and Washington, D.C.) created a committee to develop a vaccine distribution plan, only 20 plans mentioned using a health equity committee to assist with plan development.
Researchers have found that viral vaccines grown in eggs, such as the H1N1 flu vaccine, produce an antibody response against a sugar molecule found in eggs, which could have implications for the effectiveness of these vaccines.
How common COVID-19 is among infants may depend on the degree of the pandemic virus circulating in a community, a new study finds.
UC San Diego Health is now offering a verifiable digital vaccine record to its patients who have or will receive a COVID-19 vaccine. These secure online records, otherwise known as a SMART health card, can be accessed directly from the MyUCSDChart patient portal.
MADISON – The presence of a state prison in a county was associated with 11% more COVID-19 cases through July 1, 2020, according to a new study from the University of Wisconsin–Madison.
UNC-Chapel Hill scientists investigated blood samples from children enrolled in a dengue vaccine trial to identify the specific kinds of antibody responses that correlate with protection against dengue virus disease.
A groundbreaking study found that stem cells reduce the amount of virus causing AIDS, boost the body’s antiviral immunity, and restore the gut’s lymphoid follicles damaged by HIV. It provided a roadmap for multi-pronged HIV eradication strategies.
Scientists have a general idea of how viruses invade and spread in the body, but the precise mechanisms are actually not well understood, especially when it comes to Ebola virus. Olena Shtanko, Ph.D., a Staff Scientist at the Texas Biomedical Research Institute (Texas Biomed), has received more than $1 million from the National Institutes of Health (NIH) to explore different aspects of Ebola virus infection.
New York City neighborhoods that had higher levels of socioeconomic disadvantage experienced more COVID-19 infections and deaths, according to Mount Sinai scientists who created a neighborhood-level COVID-19 inequity index.
The IDSA Foundation announces a call for applications for the 2021 Microbial Pathogenesis in Alzheimer’s Disease Grant. The $1.7 million grant, an increase from $1 million in 2020, will fund the advancement of novel research into possible links between infectious diseases and the causation of Alzheimer’s disease.
A multinational effort is underway to understand and control the spread of disease among migratory birds.
Abstract: Disease-specific COVID-19 pediatric comorbidity has not been studied effectively todate. Atopy and food anaphylaxis disease states require improved characterization of SARS-CoV-2 infection risk. To provide the first such characterization, we assessed serum samples of a highlyatopic, food anaphylactic, asymptomatic…
A coalition of six U.S. subsidiary companies have sponsored a COVID-19 mobile clinic to vaccinate 10,000 maquiladora workers employed in Baja California, Mexico. UC San Diego Health is vaccinating about 1,500 workers daily.
The discovery of new possible biomarkers to predict clinical and immune responses to dengue virus infection could be critical to informing future vaccines for the mosquito-borne virus, which saw a record number of over 400 million cases in 2019.
Within the next decade, the novel coronavirus responsible for COVID-19 could become little more than a nuisance, causing no more than common cold-like coughs and sniffles. That possible future is predicted by mathematical models that incorporate lessons learned from the current pandemic on how our body’s immunity changes over time. Scientists at the University of Utah carried out the research, now published in the journal Viruses.
University of Miami Miller School of Medicine researchers report the widespread blood vessel dysfunction, or endothelial dysfunction, that results from the COVID-19 infection could contribute to erectile dysfunction, or ED, according to a study published in the World Journal of Men’s Health .
Published in the journal Proceedings of the Royal Society B, the research analyzes more palatable alternatives to the kind of social distancing mandates that threw a wrench at how businesses, schools and even family gatherings work.
After COVID-19 emerged on U.S shores, providers began reviewing the emerging basic science, translational, and clinical data to identify potentially effective treatment options. In addition, a multitude of both novel and repurposed therapeutic agents were used empirically and studied within clinical trials.
UC San Diego School of Medicine researchers discovered one way in which SARS-CoV-2 hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.
Because COVID-19 has been detected in urine and stool samples, public restrooms can be cause for concern. Researchers measured droplets generated from flushing a toilet and a urinal in a public restroom and found a substantial increase in the measured aerosol levels in the ambient environment with the total number of droplets generated in each flushing test ranging up to the tens of thousands. Due to their small size, these droplets can remain suspended for a long time.
As California opens up COVID-19 vaccination eligibility to everyone age 16 and older, UC San Diego Health sports medicine specialists Samuel Galloway, MD, and Alan Shahtaji, DO, are available to discuss what people should know about exercise before and after vaccination. Sample topics: Exercise…
UC San Diego researchers found that the chemical inhibitor K777 reduces the coronavirus’ ability to infect cell lines by blocking human enzyme cathepsin L; clinical trials are underway.
UC San Diego students will participate in nationwide clinical trial to assess if COVID-19 vaccination prevents infection and reduces risk of transmission.
The most recent data available suggests reported cases of sexually transmitted diseases (STDs) have declined. This is good news, but experts at University of California San Diego AntiViral Research Center say STD rates could soon be on the rise again.…
UC San Diego researchers discovered that patient survival from sepsis is associated with higher platelet counts, and identified two currently available drugs that protect these blood cells and improve survival in mice with sepsis.
Investigators from UC San Diego and UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus. Risk of infection is minuscule, but exists.