Asymptomatic infections may underlie recent rise in whooping cough

In a new study, scientists at La Jolla Institute for Immunology (LJI) compared the immune response of individuals who received older versus newer versions of the whooping cough vaccine. The unexpected findings may help explain the recent rise in whooping cough cases and point to potential targets for the next generation of vaccines.

Early plasma antigen levels predict illness severity and clinical outcomes in hospitalized patients with COVID-19

A large cross-sectional study conducted in 114 centers in 10 countries confirmed that plasma viral antigen can be quantified in early samples obtained from patients hospitalized with COVID-19 and is highly associated with both baseline severity of illness and clinically important patient outcomes. The findings are published in Annals of Internal Medicine.