According to a new study led by Yale Cancer Center and Department of Neurology researchers, a simple blood draw may be the first step in helping to discover tumor reactive immune or T cells to treat advanced melanoma, a deadly form of skin cancer. The findings were published today in the Journal of Experimental Medicine.Read more
UC San Diego researchers report that individual immune response to SARS-CoV-2 may be limited by a set of variable genes that code for cell surface proteins essential for the adaptive immune system. The finding may help explain why COVID-19 immunity varies by individual.Read more
CLEVELAND: As part of the new Cleveland Innovation District announced today by State of Ohio Governor Mike DeWine, Lieutenant Governor Jon Husted, JobsOhio and Ohio Development Services Agency, Cleveland Clinic will significantly expand its global commitment to infectious disease research and translational programs to form the Global Center for Pathogen Research & Human Health.
The new Center will position Ohio as an international leader for research into emerging pathogens and virus-related diseases and will serve as a significant economic catalyst in Northeast Ohio. Funding comes through a $500 million investment from the State of Ohio, JobsOhio and Cleveland Clinic.
A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.Read more
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response.Read more
New research by scientists at the University of Chicago suggests a person’s antibody response to influenza viruses is dramatically shaped by their pre-existing immunity, and that the quality of this response differs in individuals who are vaccinated or naturally infected. Their results highlight the importance of receiving the annual flu vaccine to induce the most protective immune response.Read more
Millions around the world have waited for news about a COVID-19 vaccine, regarding it as the beginning of the end for the global pandemic and a herald for the eventual return to “normal life.” Recent announcements from pharmaceutical companies Pfizer and Moderna that their respective late-stage vaccine trials have shown a 90% or better effectiveness rate have received international applause, excitement furthered with estimates that doses could be ready as early as December.Read more
A vaccine created to prevent the recurrence of the deadly skin cancer melanoma is about twice as effective when patients also receive two components that boost the number and effectiveness of immune system cells called dendritic cells, according to phase 2 clinical trial results published in Nature Cancer in November.Read more
The COVID-19 Research Symposium, hosted by the Mount Sinai Clinical Intelligence Center (MSCIC), is a one-day comprehensive review of advances in research by the Mount Sinai Health System to better understand and treat the coronavirus known as COVID-19.Read more
The upcoming holiday season is sure to look a lot different. According to a recent Filtrete™ Brand survey, more than halfRead more
Early results from a University of Arkansas for Medical Sciences (UAMS)-led COVID-19 antibody study show that 3.5% of Arkansans have been infected with the novel coronavirus.Read more
This year, many traditional holiday events and venues are cancelled, long-distance travel is unlikely, and large holiday parties are onRead more