Microchip Models of Human Lungs Enable Better Understanding of Disease, Immune Response

In Biomicrofluidics, researchers review lung-on-chip technologies that represent the vital properties of lung tissue and are capable of recapitulating the fundamental aspects of various pathologies. The researchers reviewed various lung-on-chips and their applications in examining, diagnosing, and treating human viruses, including the coronavirus that causes COVID-19. The knowledge accumulated paves the way to use these models to study the interaction of several human respiratory viruses with the airway epithelium and alveolus in an organ-relevant setting.

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Speakers Announced for Virtual Experimental Biology 2021 Meeting

Renowned scientists—including Nobel laureates, research pioneers and celebrated educators—will speak at the virtual Experimental Biology (EB) 2021 meeting, to be held April 27–30. Bringing together thousands of life scientists in one interdisciplinary community, EB showcases the latest advances in anatomy, biochemistry, molecular biology, investigative pathology, pharmacology and physiology.

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Novel Coronavirus Circulated Undetected Months before First COVID-19 Cases in Wuhan, China

Using molecular dating tools and epidemiological simulations, researchers at UC San Diego School of Medicine estimate that the SARS-CoV-2 virus likely circulated undetected for two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.

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Press Registration Now Open for Virtual Experimental Biology 2021 Meeting

Complimentary press passes are now available for the virtual Experimental Biology (EB) 2021 meeting, to be held April 27–30. EB is the annual meeting of five scientific societies bringing together thousands of scientists and 25 guest societies in one interdisciplinary community.

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Cone Snail Venom Shows Potential for Treating Severe Malaria

Using venom from the Conus nux, a sea snail, a first-of-its-kind study suggests these conotoxins could potentially treat malaria. The study provides important leads toward the development of new and cost-effective anti-adhesion or blockade-therapy drugs aimed at counteracting the pathology of severe malaria. Similarly, mitigation of emerging diseases like COVID-19 also could benefit from conotoxins as potential inhibitors of protein-protein interactions as treatment. Venom peptides from cone snails has the potential to treat myriad diseases using blockage therapies.

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Go Inside the Most Innovative Minds in Science and Medicine on “Real, Smart People,” a New Podcast

Podcast from the Icahn School of Medicine at Mount Sinai offers a glimpse into the real story of how science and medicine moves forward, one smart person at a time.

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Memorial Sloan Kettering Awards and Appointments

Memorial Sloan Kettering Cancer Center (MSK) announces its most recent awards and appointments for the institution’s physicians, scientists, nurses, and staff.

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Thomas J. Fuchs, DSc, Named Dean of Artificial Intelligence and Human Health and Co-Director of the Hasso Plattner Institute for Digital Health at Mount Sinai

Appointment Advances Health System’s Role as Leader in AI and Digital Health

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Memorial Sloan Kettering Awards and Appointments

Memorial Sloan Kettering Cancer Center (MSK) announces its most recent awards and appointments for the institution’s physicians, scientists, nurses, and staff.

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Study Finds High Levels of Toxic Pollutants in Stranded Dolphins and Whales

Researchers examined toxins in tissue concentrations and pathology data from 83 stranded dolphins and whales from 2012 to 2018. They looked at 11 different animal species to test for 17 different substances. The study is the first to report on concentrations in blubber tissues of stranded cetaceans of atrazine, DEP, NPE and triclosan. It also is the first to report concentrations of toxicants in a white-beaked dolphin and in Gervais’ beaked whales.

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Brain Cancer: UVA IDs Gene Responsible for Deadly Glioblastoma

The discovery of the oncogene responsible for glioblastoma could be the brain tumor’s Achilles’ heel, one researcher says.

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A Different Chia-PET Provides Insight Into Prostate Cancer

DALLAS – July 6, 2020 – UT Southwestern researchers have identified vast webs of small snippets of the genome that interact with each other and with genes to promote prostate cancer. Their findings, published June 22 in the Journal of Clinical Investigation, could lead to new ways to treat the most common type of malignancy in American men other than skin cancer.

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Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

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Mount Sinai Health System and Renalytix Form Joint Venture, Kantaro Biosciences, To Develop and Scale Production of COVID Antibody Test Kits

– Kantaro Biosciences partners with Bio-Techne for manufacturing and global kit distribution
– Scaled kit production to enable clinical laboratories to conduct 10M tests per month is planned to begin in July

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Mount Sinai’s Blood Test to Detect Antibodies to COVID-19 Receives Emergency Use Authorization From U.S. Food and Drug Administration

Today, the Mount Sinai Laboratory (MSL), Center for Clinical Laboratories received emergency use authorization from the U.S. Food and Drug Administration (FDA) for an antibody test that was developed, validated, and launched at Mount Sinai by a team of internationally renowned researchers and clinicians of the Icahn School of Medicine at Mount Sinai. This test detects the presence or absence of antibodies to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) and importantly, may also be used to identify positive specimens with an antibody titer (level) up to a dilution of 1:2880 for the identification of individuals with higher antibody titers.

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Mount Sinai Study Finds First Cases of COVID-19 in New York City are Primarily from European and US Sources

First definitive molecular epidemiology study of SARS-CoV-2 in New York City to describe the route by which the virus arrived

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Mount Sinai Developing an “End-to-End” Diagnostics Solution for COVID-19 That Incorporates Diagnosis, Treatment Selection, and Monitoring of Disease Course

An expert team of researchers and clinicians have been working together to design, validate, and implement an “end-to-end” clinical pathology laboratory solution that will allow for the testing of approximately several hundred people per day in order to rapidly diagnose and help guide the selection of treatment and monitor disease course.

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CAP Opens Comment Period for MMR/MSI Testing, Advancing Care for Patients with Cancer

Recognizing a need for evidence-based recommendations to guide molecular testing in the management of patients with cancer, the College of American Pathologists (CAP) and three collaborating societies are developing a clinical guideline for testing DNA mismatch repair (MMR) and microsatellite instability (MSI) status in patients with a range of cancer types.

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Speakers announced for 2020 Experimental Biology meeting

Renowned scientists including Nobel laureates, research pioneers and celebrated educators will convene at the Experimental Biology (EB) 2020 meeting, to be held April 4–7 in San Diego. Bringing together more than 12,000 life scientists in one interdisciplinary community, EB showcases the latest advances in anatomy, biochemistry, molecular biology, investigative pathology, pharmacology and physiology.

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Combination of More Hospitalizations and Brain Pathologies Linked to Faster Cognitive Decline

Older people who experienced more hospitalizations and also had more Alzheimer’s pathology in their brain experienced the fastest rates of cognitive decline, according to study results published in the October 15 online issue of the Annals of Neurology.

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