Microchip Models of Human Lungs Enable Better Understanding of Disease, Immune Response

In Biomicrofluidics, researchers review lung-on-chip technologies that represent the vital properties of lung tissue and are capable of recapitulating the fundamental aspects of various pathologies. The researchers reviewed various lung-on-chips and their applications in examining, diagnosing, and treating human viruses, including the coronavirus that causes COVID-19. The knowledge accumulated paves the way to use these models to study the interaction of several human respiratory viruses with the airway epithelium and alveolus in an organ-relevant setting.