A grant from the National Institutes of Health will allow a Penn State College of Medicine researcher to lead a three-year, multi-institution project to create an atlas of developing mice brains.
While studied for nearly a century, little is known about how cavefish brains differ. A study is the first to look inside their brains with millimeter resolution to start to understand how the individual neurons and brain regions that drive complex behaviors, including sleep and feeding have evolved. This work has broad implications for the understanding of how brains evolve in many different animal models and is hoped to be widely used by the scientific community.
Patients with Alzheimer’s disease frequently suffer from spatial memory loss, such as no recognition of where they are, and forgetting where they put their belongings. They often show a wandering symptom, which is also a feature of spatial memory impairment. Until now, the brain network mechanism that causes spatial memory impairment had been unclear.