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UrduFor outstanding contributions to engineering of biomimetic tissue-on-chip technologies and organoids for disease modeling and regenerative medicine, ASU’s Mehdi Nikkhah has been inducted as a Fellow into the American Institute for Medical and Biomedical Engineering.
Tag: Tumor Growth
DNA organization influences the growth of deadly brain tumors in response to neuronal signals
A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumour known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading, this discovery paves the way for further research into new treatments for brain tumours.
Novel small molecule 5D4 disrupts several molecular pathways, including MYC, that lead to cancer growth
Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models.
Tissue- and Cell-specific Properties of Specialized Cells Affect How Quickly Tumors Form in Intestinal Cancer
Article title: Tissue and cell specific properties of enterochromaffin cells affect the fate of tumorigenesis toward non-endocrine adenocarcinoma of the small intestine Authors: Yoshitatsu Sei, Jianying Feng, Xilin Zhao, Pradeep Dagur, J. Philip McCoy, Juanita L. Merchant, Stephen A. Wank…
Stopping a rare childhood cancer in its tracks
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show that the cells causing this cancer can essentially be reprogrammed with the flick of a genetic switch.
New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children
Although rare compared to adult liver cancers, hepatoblastoma is the most common pediatric liver malignancy, and its incidence is increasing.
Researchers Identify a Regulator of Breast Cancer Development
UT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women.
Disarming the Body’s Defenders
Study shows how certain cancers neutralize T cells to subvert the immune system and help tumors grow
Discovery of cell protein that keeps Kaposi’s sarcoma herpesvirus dormant
A study led by UC Davis Cancer Center identified a binding protein in cancer cell’s nucleus, known as CHD4, as a critical agent keeping Kaposi’s sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body’s immune system. CHD4 is linked to cancer cell growth in many types of cancers.
Tiny Nanospindles Enhance Use of Ultrasound to Fight Cancer
Ultrasound can be used to treat cancer when used in combination with molecules that sensitize the system to sound waves. These sonosensitizers generate toxic reactive oxygen species that attack and kill tumor cells. In Applied Physics Review, scientists report a new type of sonosensitizer based on a vanadium-doped titanium dioxide that enhances the amount of damage ultrasound inflicts on tumors. Studies in mice showed that tumor growth was markedly suppressed when compared to a control group.
Moderate-pace Walking Shrunk Pancreatic Cancer Tumors and Increased Cancer-killing Cells, Small Study Shows
Emily LaVoy, PhD, of the University of Houston, and colleagues explored the effects of moderate-intensity exercise on a mouse model of pancreatic cancer. Pancreatic cancer can be a particularly dangerous form of cancer because it is often diagnosed in later stages and spreads quickly. Though the trial sample was small—thus warranting further study—the results were optimistic.
Exercise Slowed Tumor Growth in Mouse Model of Prostate Cancer
Kai Zou, PhD, and his doctoral student, Benjamin Kugler, MS, of the University of Massachusetts Boston, examined the link between physical activity and tumor growth in a mouse model.
Exercise May Improve Effects of Radiation Therapy in Prostate Cancer
Cancer is the second leading cause of death around the world after heart disease. This week, researchers exploring the effects of exercise as a natural preventive tool and noninvasive treatment for cancer will present their work at the American Physiological Society (APS) Integrative Physiology of Exercise conference.