New addition to standard-of-care treatments for non-small-cell lung cancer patients has potential to increase progression-free survival

Houston Methodist researchers have developed an advanced mathematical model that predicts how novel treatment combinations could significantly extend progression-free survival for patients with non-small-cell lung cancer (NSCLC), the most common type of lung cancer.

Researcher’s microscale tech is chipping away at cancer, organ failure and neurological disease

For outstanding contributions to engineering of biomimetic tissue-on-chip technologies and organoids for disease modeling and regenerative medicine, ASU’s Mehdi Nikkhah has been inducted as a Fellow into the American Institute for Medical and Biomedical Engineering.

DNA organization influences the growth of deadly brain tumors in response to neuronal signals

A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumour known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading, this discovery paves the way for further research into new treatments for brain tumours.

Discovery of cell protein that keeps Kaposi’s sarcoma herpesvirus dormant

A study led by UC Davis Cancer Center identified a binding protein in cancer cell’s nucleus, known as CHD4, as a critical agent keeping Kaposi’s sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body’s immune system. CHD4 is linked to cancer cell growth in many types of cancers.

Tiny Nanospindles Enhance Use of Ultrasound to Fight Cancer

Ultrasound can be used to treat cancer when used in combination with molecules that sensitize the system to sound waves. These sonosensitizers generate toxic reactive oxygen species that attack and kill tumor cells. In Applied Physics Review, scientists report a new type of sonosensitizer based on a vanadium-doped titanium dioxide that enhances the amount of damage ultrasound inflicts on tumors. Studies in mice showed that tumor growth was markedly suppressed when compared to a control group.

Moderate-pace Walking Shrunk Pancreatic Cancer Tumors and Increased Cancer-killing Cells, Small Study Shows

Emily LaVoy, PhD, of the University of Houston, and colleagues explored the effects of moderate-intensity exercise on a mouse model of pancreatic cancer. Pancreatic cancer can be a particularly dangerous form of cancer because it is often diagnosed in later stages and spreads quickly. Though the trial sample was small—thus warranting further study—the results were optimistic.

Exercise May Improve Effects of Radiation Therapy in Prostate Cancer

Cancer is the second leading cause of death around the world after heart disease. This week, researchers exploring the effects of exercise as a natural preventive tool and noninvasive treatment for cancer will present their work at the American Physiological Society (APS) Integrative Physiology of Exercise conference.