Cedars-Sinai Guerin Children’s is building a formidable pediatric research enterprise aimed at identifying the genetic underpinnings of childhood diseases and developing novel therapies.
Tag: Precision Medicine
William K. Oh, MD, Joins Yale Cancer Center and Smilow Cancer Hospital
William K. Oh, MD, has been appointed as Medical Director of Smilow Cancer Hospital at Greenwich Hospital, as well as Director of Precision Medicine for Yale Cancer Center and Smilow Cancer Hospital.
BePRECISE consortium unveils guidelines to enhance reporting in precision medicine research
The inaugural reporting guidelines for precision medicine research, of which Wits University Professor Michèle Ramsay is co-author, have been published in Nature Medicine.
Meeting preview: Hot topics at NUTRITION 2024
Thousands of top nutrition experts will gather next month for a dynamic program of research announcements, policy discussions and award lectures at NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition. Reporters and bloggers are invited to apply for a complimentary press pass to attend the meeting in Chicago from June 29–July 2.
Sylvester Cancer Launches New Brain Tumor Institute to Personalize Brain Cancer Treatment
Sylvester Comprehensive Cancer Center today announced establishment of the Sylvester Brain Tumor Institute. It will focus on personalized medicine approaches for treating all patients with brain tumors.
Cancer cell–immune cell interactions predict immunotherapy response
By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.
APOLLO researchers uncover new target for ovarian cancer treatment
Scientists have identified a new target in ovarian cancer that is particularly vulnerable to chemotherapy. The discovery will allow researchers to better predict how this cancer will behave, particularly the most common and lethal, high-grade serous ovarian cancer (HGSOC). Ovarian cancer is one of the leading causes of cancer deaths among women.
Precision medicine navigators increase genomic testing rates for Black patients with prostate cancer
The presence of a clinical navigator to act as a liaison between people with prostate cancer and the health care system greatly increases the likelihood that patients, especially Black patients, will receive advanced testing that can help predict the severity of their disease and guide treatment, a new study suggests.
CureMD Announces Strategic Collaboration with Tempus to Integrate Genomic Testing Functionality in EHR
CureMD, a leading provider of comprehensive technology solutions for community oncology, is proud to announce its partnership with Tempus, a leader in artificial intelligence and precision medicine, to integrate Tempus’ advanced genomic testing capabilities into CureMD’s cutting-edge Electronic Health Record (EHR) system.
New Bladder Cancer Classification Predicts Treatment Response
Investigators from Cedars-Sinai Cancer, working in collaboration with colleagues in Colorado and the Netherlands, have identified a specific type of bladder cancer most likely to resist first-line treatment.
Study finds genetic screening of adults would be cost-effective
An exhaustive cost-benefit analysis of population genetic testing published in Annals of Internal Medicine concludes with a recommendation to U.S. health policymakers to adopt routine testing of adults ages 40 and under for three genetic conditions posing high risk of life-threatening illness.
Leading Physician-Scientist Dr. Bradley A. Maron Appointed Senior Associate Dean for Precision Medicine at UMSOM and Co-Director of new University of Maryland Institute for Health Computing (UM-IHC) at UMB
University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Bradley A. Maron, MD, Associate Professor of Medicine at Brigham & Women’s Hospital (BWH) and Harvard Medical School (HMS), and Co-Director of the Pulmonary Vascular Disease Center at the VA Boston Healthcare System, has been appointed Co-Director of the UMB’s new Institute for Health Computing (UM-IHC), Director of Scientific Operations for the UM-IHC at UMSOM, as well as Senior Associate Dean for Precision Medicine at the UMSOM, effective May 1, 2023.
IU neuroscientists lead new study laying groundwork for Alzheimer’s disease precision medicine
A 5-year, $41 million study will help researchers better understand the biological pathways underlying Alzheimer’s disease and ultimately create more personalized patient care through the development of a blood test for multiple pathways implicated in the disease – enabling earlier and less-invasive diagnosis.
An extra X chromosome-linked gene may explain decreased viral infection severity in females
Researchers may have found why viral infections hit males more severely than females. They found that female mouse and human NK cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost NK cell anti-viral function, while repressing NK cell numbers.
Pharmacotyping of childhood leukemia provides a blueprint for ‘true precision medicine’
Scientists from St. Jude Children’s Research Hospital performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic leukemia across genomic subtypes and its association with treatment response.
Wearable Activity Trackers Can Be Used to Determine Health Metrics That Could Support Clinical Care
A new Johns Hopkins study shows that data gathered from wearable activity trackers can be used to obtain several metrics associated with the user’s general physical health and cardiovascular health status.
KU Medical Center researchers receive R01 grant from National Cancer Institute to increase targeted cancer treatments to rural cancer patients
TEAMSPORT will create a standardized approach to ordering genomic tests and adapt it for use in community cancer centers, where most cancer patients receive testing and treatment.
Trailblazing scientists discuss exposome research, precision nutrition at Mayo Clinic’s Individualizing Medicine Conference
The next frontier in individualized medicine is here. Mayo Clinic’s 11th annual Individualizing Medicine Conference on Nov. 2–3 will focus on “Exploring the Exposome” — the cumulative measure of environmental influences and associated biological responses throughout the life span of a person, and how those exposures relate to health and disease.
Physician Scientist to Lead Breast Oncology Program
Yuan Yuan, MD, PhD, a breast medical oncologist and physician scientist who specializes in triple-negative breast cancer and breast cancer immunotherapy, has joined Cedars-Sinai Cancer as director of Breast Oncology. Yuan will treat patients at Cedars-Sinai and at Huntington Cancer Center, an affiliate of Cedars-Sinai Cancer.
Advancing Precision Oncology, Ochsner Health First to Fully Integrate with Tempus and Epic’s Genomics Module
Ochsner Health, through its Precision Medicine Program, is the first in the nation to incorporate Epic’s Orders and Results Anywhere integration with its Genomics module.
Mount Sinai Launches Large-Scale Genetic Sequencing Project with the Regeneron Genetics Center
Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.
ACP offers guidance on the ethical use of genetic testing and precision medicine
A new position paper from the American College of Physicians (ACP) offers guidance regarding ethical decision-making for the integration of precision medicine and genetic testing into internal medicine. ACP’s advice is published in Annals of Internal Medicine.
Chemo-Radio-Immunotherapy Treats Local Cancers, Minimizes Side Effects
In a study published July 5, 2022, researchers at University of California San Diego School of Medicine present a three-prong approach to targeting local cancers while minimizing adverse effects in other parts of the body. The precision cancer therapy combines…
Groundbreaking for Major Expansion of University of Maryland Greenebaum Comprehensive Cancer Center
The University of Maryland Medical Center celebrates the groundbreaking of a nine-story patient care tower – the Roslyn and Leonard Stoler Center for Advanced Medicine – that will become the new home of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center. The $219 million building will enable the cancer center to provide the most technologically advanced, integrated care to cancer patients throughout Maryland and the region well into the future
New Approach Methodologies, Single Cell RNAseq, and More Featured in 2021 Toxicological Sciences
Toxicological Sciences delivers cutting-edge research in toxicology in the areas of clinical and translational toxicology, emerging technologies, and more in the August 2021 issue.
Genetics/biotech expert offers comments & availability on IVG (in vitro gametogenesis) major breakthrough
A groundbreaking study demonstrating the most advanced form of in vitro gametogenesis (making eggs from stem cells, IVG) was published Thursday in Science. See STAT’s coverage of the study. Regarding the study and breakthrough, Dr. Kevin Doxzen offers the below comments…
Precision medicine helps identify “at-risk rapid decliners” in early-stage kidney disease
A novel therapeutic may halt rapid kidney function in some type 1 diabetic kidney disease patients.
How to Reduce Obesity among Latino Children, with Precision
Researchers at UC San Diego Altman Clinical and Translational Research Institute have received $3 million to create a precision, community-based program to address specific health problems related to adverse childhood experiences that contribute to childhood obesity among Latinos.
The Medicine in Eye Drops Needs a Disguise to Sneak Past Your Tears
Scientists use engineered protein coating that binds to receptors on the surface of corneal cells to improve drug uptake.
New wiki on salivary proteins may transform diagnostic testing and personalized medicine
To improve the development of new saliva-based diagnostic tests and personalized medicine, the National Institute of Dental and Craniofacial Research (NIDCR) has supported the development of the Human Salivary Proteome Wiki, the first public platform that catalogs and curates data on each of the thousands of proteins within our saliva.
Lurie Children’s Study to Use Soy Isoflavones in a Precision Medicine Approach to Prevent Wheezing and Asthmatic Inflammation in High Risk Infants
Rajesh Kumar, MD, and Jacqueline Pongracic, MD, from Ann & Robert H. Lurie Children’s Hospital of Chicago received $3 million from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) for a site-specific clinical trial on whether a soy supplement in infancy can prevent asthma in children with a high-risk genetic variation. This will be one of the earliest precision medicine approaches to asthma prevention.
Johns Hopkins Medicine Receives $16 Million Gift
Donation to support clinical scientists with precision medicine and vision researchPhilip Van Horn Gerdine. Credit: Pierce Harman Photography
Scientists Scour Genes of 53,000+ People to Better Battle Dangerous Diseases
International Project Set to Boost Precision Medicine, Reduce Health Disparities
Mount Sinai Study Reveals Genetic and Cellular Mechanisms of Crohn’s Disease
New study identifies a novel approach for tailored treatment that could be more effective for patients with the chronic disease
Precision medicine, digital technology hold potential as powerful tools against tuberculosis
The global fight against tuberculosis is gaining some powerful tools. Precision medicine — already used to personalize diagnosis and treatment of noncommunicable diseases such as cancer — and health care technologies such as telemedicine have the potential to advance the prevention and treatment of tuberculosis, says Zelalem Temesgen, M.D., an infectious diseases expert and medical director of the Mayo Clinic Center for Tuberculosis.
Combination thyroid hormone therapies treat hypothyroidism as well as levothyroxine
Treatment of hypothyroidism, which results from an underactive thyroid gland, should be individualized and consideration should be given to alternatives to the first-line therapy, including desiccated thyroid extract and combination therapy to replace the body’s two main thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Results of their new randomized clinical study are being presented at ENDO 2021, the Endocrine Society’s annual meeting.
Corrona Announces Name Change to CorEvitas and Expanded Strategic Direction
Corrona, LLC, a leading provider of real-world evidence solutions, announced today that it has changed its name to CorEvitas [kohr-eh’-vi-tahs].
Healthcare Executive Martha R. Temple Joins Coriell Life Sciences Board of Directors
Genetic science is a game-changer for medication safety and healthcare overall, and Coriell Life Sciences is leading the way in unlocking its full potential through precision medicine.
Biotechnology research and policy expert joins Thunderbird School of Global Management and Sandra Day O’Connor College of Law at ASU through World Economic Forum fellowship
Thunderbird School of Global Management announces the first of two prestigious Hoffmann Fellowships appointed in collaboration with the World Economic Forum for post-doctoral research and policy innovation at the intersection of society, science and technology.
Mount Sinai Researchers Identify and Characterize Three Molecular Subtypes of Alzheimer’s Disease
Critical Step Toward Developing Precision Medicine Treatments
Roswell Park Experts Use Gene Sequencing to Quantify Risk of Skin Cancer Long Before Damage is Visible
In a study published today in the journal Science Advances, a team from Roswell Park details a method to measure the abundance of cancer-related early changes to skin tissue long before the damage becomes visible to the eye.
Advances in COVID-19 Testing, Artificial Intelligence, Cancer Therapies, and The Future of Precision Medicine to Be Explored at The All-Virtual 2020 AACC Annual Scientific Meeting
In the wake of the novel coronavirus pandemic, the need for reliable, accurate, and accessible laboratory testing is more evident than ever before. At the 2020 AACC Annual Scientific Meeting & Clinical Lab Expo, laboratory medicine experts will present the cutting-edge research and technology that is revolutionizing clinical testing and patient care for COVID-19 and across the spectrum of healthcare.
Coriell Life Sciences Wins Two Prestigious Industry Awards
Coriell Life Sciences, a trusted and innovative precision medicine organization, is honored to accept two industry awards:
EHIR’s Fall 2020 Traction Award
Healthcare Tech Outlook’s Top Precision Medicine Providers in Europe
UCLA Health and Regeneron Genetics Center enter research collaboration to provide whole exome sequencing for UCLA patients
UCLA Health has entered into a collaborative research agreement with the Regeneron Genetics Center (RGC) to provide whole exome sequencing for 150,000 UCLA Health patients
The Future of Precision Medicine
Precision medicine is a rapidly growing approach to health care that focuses on finding treatments and interventions that work for people based on their genetic makeup, rather than their symptoms.
Zeeshan Ahmed, director of the new Ahmed Lab at Rutgers Institute for Health, Health Care Policy and Aging Research, discusses the future of precision medicine, what needs to be done to successfully analyze the data necessary to develop individualized treatments and the role genetics play during the COVID-19 pandemic.
Thomas J. Fuchs, DSc, Named Dean of Artificial Intelligence and Human Health and Co-Director of the Hasso Plattner Institute for Digital Health at Mount Sinai
Appointment Advances Health System’s Role as Leader in AI and Digital Health
Research Teams Creates Device Bringing Precision Medicine to Field of Ophthalmology
Innovative device ensures doctors obtain adequate fluid samples from the eye, helping with diagnosis and individualized treatment plans for patients.
Johns Hopkins Researchers Offer Lessons Learned From Early Covid-19 Patients
Using a combination of demographic and clinical data gathered from seven weeks of COVID-19 patient care early in the coronavirus pandemic, Johns Hopkins researchers today published a “prediction model” they say can help other hospitals care for COVID-19 patients — and make important decisions about planning and resource allocations.
UChicago bioinformatics team to create data infrastructure for global pediatric cancer initiative
The University of Chicago Pediatric Cancer Data Commons and The Leukemia and Lymphoma Society are working together to bring precision medicine to children and young adults with acute leukemia.
Who Could Benefit From Exercise and Behavioral Treatment?
Aerobic exercise clearly benefits young adults with major depression, and a Rutgers-led study suggests it may be possible to predict those who would benefit from behavioral therapy with exercise. Unique to this precision medicine study, published in the journal Psychological Medicine, is an assessment of cognitive control and reward-related brain activity, two facets of brain function that are impaired in people with depression. Like previous studies, this one showed that aerobic exercise helps young adults with major depression.