Johns Hopkins Medicine Announces Microsoft Azure Will Become Its Preferred Cloud Platform for Its inHealth Precision Medicine Initiative

Johns Hopkins Medicine (JHM) today announced a five-year relationship with Microsoft Corp. centered on Microsoft’s Azure and analytical tools that will support new discoveries, as part of JHM’s inHealth precision medicine initiative. The work will bring together JHM’s leading global research expertise with the power of Microsoft Azure and its artificial intelligence (AI) capabilities and flexible infrastructure to advance JHM’s discoveries that will benefit personalized health care. Johns Hopkins will maintain total control over its data.

Read more

FAU Medicine Ushers in New Research Phase to Prevent Dementia

FAU’s Schmidt College of Medicine and The Harry T. Mangurian, Jr. Foundation have joined forces again to usher in a new phase of research to prevent dementia. The extension of a three-year, $3 million grant from the foundation will launch the new FAU Center for Brain Health. The grant supports precision medicine approaches to prevent dementia, which will be further strengthened by leveraging multiple patient-centered platforms through state-of-the-art transdisciplinary approaches.

Read more

UCLA Health’s Dr. Clara Lajonchere elected Chair of the California Precision Medicine Advisory Council

Dr. Clara Lajonchere, deputy director of the Institute for Precision Health at UCLA Health, has been elected chair of the new California Precision Medicine Advisory Council.

Read more

First-of-its-Kind Personalized ‘COVID-19 Risk Score’ Launches to Enable Safer Re-opening and Return to Work Plans

Coriell Life Sciences is rolling out a new tool in the fight against COVID-19: personalized COVID-19 Risk Scores designed to enable safer re-opening and return to work plans (especially given the recent release of the CDC guidelines for re-opening).

Read more

Calibrated approach to AI and deep learning models could more reliably diagnose and treat disease

In a recent preprint (available through Cornell University’s open access website arXiv), a team led by a Lawrence Livermore National Laboratory computer scientist proposes a novel deep learning approach aimed at improving the reliability of classifier models designed for predicting disease types from diagnostic images, with an additional goal of enabling interpretability by a medical expert without sacrificing accuracy. The approach uses a concept called confidence calibration, which systematically adjusts the model’s predictions to match the human expert’s expectations in the real world.

Read more

Researchers Identify Mechanism to Explain Role of Certain Gene Mutations in Kidney Disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine (UMSOM) have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome. Using a drosophila (fruit fly) model, they found mutations in genes that code for certain proteins lead to a disruption of the recycling of the cell membrane.

Read more

Henry Ford Health System Receives $25 Million Gift, Largest Single Donation in its History

Nationally-known developer Chris Jeffries and his wife Lisa have donated $25 million to Henry Ford Health System, the largest single gift from an individual in the health system’s 105-year history. This historic gift will rapidly accelerate the growth and expansion of Henry Ford’s Precision Medicine program, with the ultimate goal of creating a Precision Health Center. The efforts will have a robust focus on the advancement of cancer research and treatment, while also expanding to other medical specialties treating behavioral health, cardiovascular and metabolic diseases.

Read more

PECASE Honoree Sohini Ramachandran Studies the Genetic Foundations of Traits in Diverse Populations

NIGMS grantee and presidential award recipient Sohini Ramachandran, Ph.D., is challenging our understanding of genetic variation among human populations. She discusses her research on how the genetic composition of traits and diseases varies among populations, the value of statistical and computational work in human genetics, and what this all means for patient treatment.

Read more

Coriell Researchers Identify SNP Associated with Obesity Risk

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person’s risk for the disease. Coriell researchers have found a new genetic indicator of obesity risk and bolstered the understood importance of one gene’s role in obesity risk.

Read more

Superior “Bio-Ink” for 3D Printing Pioneered

Rutgers biomedical engineers have developed a “bio-ink” for 3D printed materials that could serve as scaffolds for growing human tissues to repair or replace damaged ones in the body. Their study was published in the journal Biointerphases.

Read more