Brain Cancer | sciencenewsnet.in

Researchers link cellular transport pathway to aggressive brain cancer

January 14, 2021 sarah Jonas Brain Cancer, Cell Biology, Glioblastoma

Researchers at McGill University have identified a new cellular pathway that limits the growth and spread of brain tumors by controlling the recycling of cell surface receptor proteins. The study, which will be published January 14 in the Journal of Cell Biology (JCB), suggests that the pathway, which involves a protein called Rab35, is defective in many patients with glioblastoma and that restoring Rab35’s activity could be a new therapeutic strategy for this deadly form of brain cancer.

Feature

From Glioblastoma to Endurance Races: A Story of Tenacity

January 12, 2021 sarah Jonas Brain Cancer, Cedars-Sinai, Glioblastoma, Keith Black

Anyone who sees Colin Clark, 57, running, cycling or swimming around the Big Island of Hawaii, likely notices his athleticism and the smile permanently adorning his face.

Research Results

New Treatment Approach for a Common Glioma Subtype Shows Promise in Animal Models

December 17, 2020 sarah Jonas Brain Cancer, Cancer, Glioma, Immunotherapy

A combination approach to treating a common subtype of glioma — which includes metabolic reprogramming and immunotherapy — led to complete tumor regression in 60% of study mice.

Announcement

Netflix to feature Mayo Clinic neurosurgeon in new documentary series

December 4, 2020 sarah Jonas Brain Cancer, Brain Surgery, Mayo Clinic, Neurosurgery

Netflix, a leading streaming entertainment service featuring TV series, documentaries and feature films across a wide variety of genres and languages, will soon begin airing a new documentary series, “The Surgeon’s Cut,” which features an episode about Alfredo Quinones-Hinojosa, M.D., a Mayo Clinic neurosurgeon.

Feature

A real life “Superman” celebrates 5 years of survival from one of the deadliest cancers

November 24, 2020 sarah Jonas Brain Cancer, Brain Tumors, Cancer Survivor, Neurosurgery

Story of a man who celebrated his five-year survival with GBM. He received 5-ALA prior to surgery, which helps the surgeon see more of the tumor for removal, and he was in a Phase 1 clinical trial.

Research Results

New targeted therapy blocks metabolism in brain cancer cells with genetic vulnerability

November 23, 2020 sarah Jonas Brain Cancer, glycolysis, MD Anderson Cancer Center, Metabolism, Targeted Therapy

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects. Preclinical studies found the small-molecule enolase inhibitor to be effective in killing brain cancer cells that were missing ENO1, one of two genes encoding the enolase enzyme.

Research Results

Personalized drug screens could guide treatment for children with brain cancer

November 12, 2020 sarah Jonas Biopsy, Brain Cancer, Cancer, Childhood Brain Cancer, Medulloblastoma, Medulloblastoma (MB), Therapeutics, Tumor, Tumor cell

Scientists at Sanford Burnham Prebys Medical Discovery Institute, University of California San Diego School of Medicine and Hopp Children’s Cancer Center Heidelberg (KiTZ) have demonstrated that personalized drug screens can be used to identify new therapeutic candidates for medulloblastoma. The approach measures the effectiveness of therapeutics using tumor cells obtained from a biopsy and can be performed in a few days—making it one of the quickest sources of information used in clinical decision-making.

Research Results

New tools to improve care for cancer that has spread to the brain

October 6, 2020 sarah Jonas Brain Cancer, Brain Metastases, Brain Metastasis, Cancer, Cancer Care, Cancer Treatment, Hospitals, Oncology, University Of Virginia, University of Virginia Cancer Center, UVA, UVA Cancer Center, UVA Health

The tools will help doctors and patients make better-informed treatment decisions, enhance the care of brain metastases, and enable hospitals to improve the coordination and effectiveness of their interdisciplinary treatment programs.

Research Results

Study Suggests New Potential Approach Against Fatal Childhood Brain Cancer

August 13, 2020 sarah Jonas Brain Cancer, Cancer, Childhood Cancer, DIPG

In mouse models of DIPG, simultaneously attacking two metabolic pathways led to significant improvements in survival.

Research Results

Prostate Cancer Treatment Might Help Some Glioblastoma Patients

August 12, 2020 sarah Jonas Brain Cancer, Cancer, Glioblastoma

Anti-androgen therapy showed positive results in cell lines and animal models against glioblastoma, an aggressive form of brain cancer.

Research Results

Targeted ultrasound for noninvasive diagnosis of brain cancer

August 6, 2020 sarah Jonas Brain Cancer, Ultrasound

Brain tumors are typically diagnosed using MRI imaging, as taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient’s health. Researchers are developing a method to diagnose brain tumors without any incisions.

Research Results

Study Suggests New Approach to Improve Radiation Therapy Resistance in Glioblastoma

July 30, 2020 sarah Jonas Brain Cancer, Cancer, Clinical Trial, Drug Discovery, drug repurposing, Glioblastoma

Laboratory research paves the way for a clinical trial to see if an FDA-approved drug used to prevent organ transplant rejection can work against glioblastoma, a type of aggressive brain tumor.

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