Study finds improved survival for incurable brain tumor, providing ‘a crack in the armor’

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound, called ONC201, nearly doubled survival for patients with diffuse midline glioma (DMG) or diffuse intrinsic pontine glioma (DIPG), compared to previous patients.

Study: Despite failures, chemo still promising against dangerous childhood brain cancer, DIPG

Chemotherapy has been so unsuccessful against DIPG that researchers have questioned whether chemotherapy drugs are even able to reach the cancer. University of Colorado Cancer Center study shows, “… medicine does reach DIPG tissue in good quantities that have the potential to be effective against the tumor,” says lead researcher.