Henry Ford Cancer Institute is First in the World to Activate Two New Treatments in GBM AGILE Trial for Glioblastoma

Henry Ford Cancer Institute is the first site in the world to activate two new treatments for glioblastoma (GBM), the deadliest form of brain cancer, as part of a patient-centered adaptive platform trial known as GBM AGILE (Glioblastoma Adaptive Global Innovative Learning Environment).

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NIH Awards $13.8 Million for Studies on the Prevention and Treatment of Alzheimer’s Disease

Joe Verghese, M.B.B.S., M.S., an international leader in aging and cognition research at Albert Einstein College of Medicine and Montefiore Health System, has received two grants from the National Institutes of Health totaling $13.8 million to conduct studies on pre-dementia and Alzheimer’s disease.

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Does Eating Fish Protect Our Brains from Air Pollution?

Older women who eat more than one to two servings a week of baked or broiled fish or shellfish may consume enough omega-3 fatty acids to counteract the effects of air pollution on the brain, according to a new study published in the July 15, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Not all is lost for alcohol relapsers: Low risk drinking and abstinence have similar effects on brain health measures after treatment for alcohol use disorder

A study published in Alcoholism: Clinical and Experimental Research provides support for treatment goals based on reducing drinking, and not necessarily stopping completely, for people recovering from alcohol use disorder (AUD). AUD is linked to damaging reductions in the gray and white matter of certain brain regions. This tissue loss, particularly in the frontal brain lobes, can contribute to cognitive deficits and may increase the risk of relapse following treatment. In people with AUD who quit alcohol completely, brain tissue volumes can increase quite dramatically during abstinence, in parallel to cognitive improvements. Complete abstinence is also associated with improvements in general health and quality of life – therefore abstinence is the usual goal of treatment for AUD.

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FAU Medicine Ushers in New Research Phase to Prevent Dementia

FAU’s Schmidt College of Medicine and The Harry T. Mangurian, Jr. Foundation have joined forces again to usher in a new phase of research to prevent dementia. The extension of a three-year, $3 million grant from the foundation will launch the new FAU Center for Brain Health. The grant supports precision medicine approaches to prevent dementia, which will be further strengthened by leveraging multiple patient-centered platforms through state-of-the-art transdisciplinary approaches.

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Gene variants may increase susceptibility to accumulate Alzheimer’s protein tau, study shows

The toxic protein tau is a key biological feature in the brains of people with Alzheimer’s disease. Yet the factors that make people susceptible or resistant to tau accumulation are not well-understood. A preliminary Mayo Clinic study shows that inherited DNA variants may be associated with developing tau deposits in older adults. The research will be presented at the American Academy of Neurology’s 72nd Annual Meeting in Toronto April 25–May 1.

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Activating immune cells could revitalize the aging brain, study suggests

Researchers at Albany Medical College in New York have discovered that a specific type of immune cell accumulates in older brains, and that activating these cells improves the memory of aged mice. The study, which will be published February 5 in the Journal of Experimental Medicine (JEM), suggests that targeting these cells might reduce age-related cognitive decline and combat aging-associated neurodegenerative disease in humans.

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Expert Alert: Keep exercising: New study finds it’s good for your brain’s gray matter

A study in Mayo Clinic Proceedings from the German Center for Neurodegenerative Diseases provides new evidence of an association between cardiorespiratory fitness and brain health, particularly in gray matter and total brain volume — regions of the brain involved with cognitive decline and aging.

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