Feeling Constipated? You May Have a Higher Risk for Heart Disease

People with constipation may have a higher risk of having a heart attack or stroke, and the risk increases in people who also have high blood pressure. The findings of a new study are published in the American Journal of Physiology-Heart and Circulatory Physiology. The study has been chosen as an APSselect article for October.

Cannabis Exposure during Pregnancy Had Sex-dependent Effects on Rats’ Breathing in Adult Offspring

Article title: Long-term effects on cardiorespiratory and behavioral responses in male and female rats prenatally exposed to cannabinoid Authors: Luis Gustavo A. Patrone, Alana T. Frias, Gabriel T. Fantinatti, Angelita M. Stabile, Wilfried Klein, Kênia C. Bicego, Luciane H. Gargaglioni From the…

Older Women Are at Greater Risk of Heat Stress Than Older Men

Article title: Sex differences in heat stress vulnerability among middle-aged and older adults (PSU HEAT project) Authors: Olivia K. Leach, Rachel M. Cottle, Kat G. Fisher, S. Tony Wolf, W. Larry Kenney From the authors: “Our data confirm that women…

Exercise More, Sit Less to Manage Frailty and Hypertension Risk in Aging

A new study of middle-age and older adults looks at sex differences in frailty levels and their link with heart health. The findings suggest that moving your body more through regular exercise and sitting less can help keep both heart disease and frailty at bay as we age.

American Physiological Society Launches Women’s Health Research Initiative

The American Physiological Society announces the launch of the 2024–2025 Women’s Health Research Initiative. This groundbreaking initiative aims to advance women’s health research, addressing critical gaps in understanding conditions that uniquely or disproportionately affect women.

Men with Chronic Kidney Disease Have Higher Resting Activity in ‘Fight-or-Flight’ System than Women

Article title: Sex differences in sympathetic activity and vascular stiffness in adults with chronic kidney disease (CKD) Authors: Matias G. Zanuzzi, Jinhee Jeong, Dana R. DaCosta, Jeanie Park From the authors: “We show for the first time that males with…

Sex Differences in Fat Storage during Military Training Help Women Preserve Lean Mass

Article title: Sex differences in body composition and serum metabolome responses to sustained, physical training suggest enhanced fat oxidation in women compared with men Authors: Meaghan E. Beckner, Lauren Thompson, Patrick N. Radcliffe, Rebecca Cherian, Marques Wilson, Nicholas Barringer, Lee…

Gene Expression in Kidneys Is Regulated by the Microbiome in Sex- and Tissue-specific Ways

Article title: Commensal microbiota regulate renal gene expression in a sex-specific manner Authors: Brittni N. Moore and Jennifer L. Pluznick From the authors: “This report demonstrates that renal gene expression is modulated by the microbiome in a sex- and tissue-specific…

Women Have Less Age-related Decrease of Gray Matter in Brain than Men

Article title: Differential reduction of gray matter volume with age in 35 cortical areas in men (more) and women (less) Authors: Peka Christova and Apostolos P. Georgopoulos From the authors: “This study showed an overall decrease of cortical gray matter…

Researchers Explore Sex Differences in Cardiovascular and Congenital Heart Diseases in People with Down Syndrome

Article title: Sex differences in cardiovascular disease and dysregulation in Down syndrome Authors: Melissa L. Bates, Anastasiia Vasileva, Laura D.M. Flores, Yana Pryakhina, Michelle Buckman, Michael H. Tomasson, Lara R. DeRuisseau From the authors: “Based on the results of our…

Biological Sex, Heart Disease Risk Factors Can Influence Relationship between Cardiorespiratory Fitness Level and Brain Blood Flow

Article title: Influence of sex and presence of cardiovascular risk factors on relations between cardiorespiratory fitness and cerebrovascular hemodynamics Authors: Wesley K. Lefferts, Cynthia M. Weiner, Sara E. Mascone, Jacqueline A. Augustine, Kevin S. Heffernan, Elizabeth C. Lefferts From the…

Heart of Aging Female Mice Produce More Collagen than Males, Develops More Scarring

Article title: Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis Authors: Aude Angelini, Jesus Ortiz-Urbina, JoAnn Trial, Anilkumar K. Reddy, Anna Malovannaya, Antrix Jain, Mark L. Entman, George E. Taffet, Katarzyna A. Cieslik From the authors:…