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UrduArticle title: Bicarbonate is the primary inducer of KCC3a expression in renal cortical B-type intercalated cells Authors: Mohammed Z. Ferdaus, Andrew S. Terker, Rainelli Koumangoye, Susan M. Wall, Eric Delpire From the authors: “KCC3a expression is stimulated in alkalemia. This…
Tag: Renal physiology
Gene Expression in Kidneys Is Regulated by the Microbiome in Sex- and Tissue-specific Ways
Article title: Commensal microbiota regulate renal gene expression in a sex-specific manner Authors: Brittni N. Moore and Jennifer L. Pluznick From the authors: “This report demonstrates that renal gene expression is modulated by the microbiome in a sex- and tissue-specific…
Chemotherapy Drug Increases Kidney Injury in Mouse Model of Lung Cancer
Article title: Lung cancer-kidney cross talk induces kidney injury, interstitial fibrosis, and enhances cisplatin-induced nephrotoxicity Authors: Andrew Orwick, Sophia M. Sears, Cierra N. Sharp, Mark A. Doll, Parag P. Shah, Levi J. Beverly, Leah J. Siskind From the authors: “This…
Researchers Present New Mathematical Model for Studying Kidney Cells
Rockville, Md. (September 13, 2022)—Research published ahead of print in the journal Function presents a new mathematical model using opossum kidney cells to study the endocytic capacity of proximal tubule cells in the kidneys. The specialized cells in the proximal…
Shift Work Disrupts Kidney Rhythms, Contributes to Kidney and Heart Disease
Article title: Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats Authors: Atlantis M. Hill, G. Ryan Crislip, Adam Stowie, Ivory Ellis, Anne Ramsey, Oscar Castanon-Cervantes, Michelle L.…
MRI Finds Circadian Variations in Men’s and Women’s Renal Blood Flow
Article title: Circadian variation in renal blood flow and kidney function in healthy volunteers monitored with noninvasive magnetic resonance imaging Authors: Per Eckerbom, Peter Hansell, Eleanor Cox, Charlotte Buchanan, Jan Weis, Fredrik Palm, Susan Francis, Per Liss From the authors: “In…
Study Reveals Mechanisms that May Drive Sex Differences in Diuretic Response
Article title: Distal convoluted tubule sexual dimorphism revealed by advanced 3D imaging Authors: Ebrahim Tahaei, Richard Coleman, Turgay Saritas, David H. Ellison, Paul A. Welling From the authors: “Female mice expressed a greater density of [sodium cotransporters] in a shorter…
Enzyme Activation after Acute Kidney Injury May Lead to Tubule Atrophy
Article title: Intratubular epithelial-mesenchymal transition and tubular atrophy after kidney injury in mice Authors: Noriyuki Yamashita, Tetsuro Kusaba, Tomohiro Nakata, Aya Tomita, Tomoharu Ida, Noriko Watanabe-Uehara, Kisho Ikeda, Takashi Kitani, Masahiro Uehara, Yuhei Kirita, Satoaki Matoba, Benjamin D. Humphreys, Keiichi Tamagaki From…